The Tyrosinase Gene of the ib Albino Mutant of the Medaka Fish Carries a Transposable Element Insertion in the Promoter Region

Pigment Cell Research

Volumn 17, Issue 2, 2004, Pages 158-164

  Iida, Atsuo ^a   Inagaki, Hidehito ^b   Suzuki, Miho ^a,c   Wakamatsu, Yuko ^a   Hori, Hiroshi ^a   Koga, Akihiko ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b FUJITA HEALTH UNIVERSITY   (Japan)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Albinism; Medaka fish; Transposable element; Tyrosinase gene

Indexed keywords

DNA FRAGMENT; MELANIN; MONOPHENOL MONOOXYGENASE;

5' UNTRANSLATED REGION; ALBINISM; ARTICLE; FISH; HOMOZYGOTE; MEDAKA FISH; MELANOGENESIS; MELANOPHORE; MOLECULAR CLONING; MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; OCULOCUTANEOUS ALBINISM; PHENOTYPE; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; TRANSCRIPTION INITIATION SITE; TRANSPOSON; WILD TYPE;

ALBINISM; ALBINISM, OCULOCUTANEOUS; ALLELES; AMINO ACID MOTIFS; ANIMALS; BASE SEQUENCE; DNA PRIMERS; DNA TRANSPOSABLE ELEMENTS; HETEROZYGOTE; HOMOZYGOTE; HUMANS; MICE; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MONOPHENOL MONOOXYGENASE; MUTATION; NUCLEOTIDES; ORYZIAS; PHENOTYPE; POINT MUTATION; POLYMERASE CHAIN REACTION; PROMOTER REGIONS (GENETICS); REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, NUCLEIC ACID; TRANSCRIPTION, GENETIC;

INSERTION SEQUENCES; MELANOPHORA; TRANSPOSONS;

EID: 1842525724     PISSN: 08935785     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1600-0749.2003.00122.x     Document Type: Article

References (22)

1. Ishikawa Y. Medakafish as a model system for vertebrate developmental genetics. Bioessays 2000;22:487-495
2. Iwamatsu T. The Integrated Book for the Biology of the Medaka (in Japanese). Okayama, Japan: Daigaku Kyoiku Publication; 1997
3. Packer A. Medaka on the move. Nat Genet 2001;28:302
4. Inagaki H, Koga A, Bessho Y, Hori H. The tyrosinase gene from medakafish: transgenic expression rescues albino mutation. Pigment Cell Res 1998;11:283-290
5. Koga A, Inagaki H, Bessho Y, Hori H. Insertion of a novel transposable element in the tyrosinase gene is responsible for an albino mutation in the medaka fish, Oryzias latipes. Mol Gen Genet 1995;249:400-405
6. Koga A, Suzuki M, Inagaki H, Bessho Y, Hori H. Transposable element in fish. Nature 1996;383:30
7. 6 mutant of the medaka fish is associated with a deletion in the tyrosinase gene. Pigment Cell Res 1999;12:252-258
8. Tomita H. Mutant genes in the medaka. In: Yamamoto T, ed. Medaka (Killifish): Biology and Strains. Tokyo: Yugakusha Publication; 1975. pp. 251-272
9. Tomita H. The lists of the mutants and strains of the medaka, common gambusia, silver crucian carp, goldfish, and golden venus fish maintained in the Laboratory of Freshwater Fish Stocks, Nagoya University. Fish Biol J Medaka 1992;4:45-47
10. Inagaki H, Bessho Y, Koga A, Hori H. Expression of the tyrosinase-encoding gene in a colorless melanophore mutant of the medaka fish, Oryzias latipes. Gene 1994;150:319-324
11. Koga A, Hori H. Homogeneity in the structure of the medaka fish transposable element Tol2. Genet Res 1999;73:7-14
12. Koga A, Hori H. The Tol2 transposable element of the medaka fish: an active DNA-based element naturally occurring in a vertebrate genome. Genes Genet Syst 2001;76:1-8
13. Izsvák Z, Ivics Z, Shimoda N, Mohn D, Okamoto H, Hackett PB. Short inverted-repeat transposable elements in teleost fish and implications for a mechanism of their amplification. J Mol Evol 1999;48:13-21
14. Ferguson CA, Kidson SH. The regulation of tyrosinase gene transcription. Pigment Cell Res 1997;10:127-138
15. Bentley NJ, Eisen T, Goding CR. Melanocyte-specific expression of the human tyrosinase promoter: activation by the microphthalmia gene product and role of the initiator. Mol Cell Biol 1994;14:7996-8006
16. Ganss R, Schutz G, Beermann F. The mouse tyrosinase gene: promoter modulation by positive and negative regulatory elements. J Biol Chem 1994;269:29808-29816
17. Koga A, Hori H. Detection of de novo insertion of the medaka fish transposable element Tol2. Genetics 2000;156:1243-1247
18. Koga A, Iida A, Kamiya M, Hayashi R, Hori H, Ishikawa Y, Tachibana A. The medaka fish Tol2 transposable element can undergo excision in human and mouse cells. J Hum Genet 2003;48:231-235
19. Oetting WS. The tyrosinase gene and oculocutaneous albinism type 1 (OCA1): a model for understanding the molecular biology of melanin formation. Pigment Cell Res 2000;13:320-325
20. Oetting WS, King RA. Molecular basis of albinism: mutations and polymorphisms of pigmentation genes associated with albinism. Hum Mutat 1999;13:99-115
21. Porter S, Larue L, Mintz B. Mosaicism of tyrosinase-locus transcription and chromatin structure in dark vs. light melanocyte clones of homozygous chinchilla-mottled mice. Dev Genet 1991;12:393-402
22. Wu M, Rinchik EM, Wilkinson E, Johnson DK. Inherited somatic mosaicism caused by an intracisternal a particle insertion in the mouse tyrosinase gene. Proc Natl Acad Sci USA 1997;94:890-894