A delay in bone marrow transplantation after partial conditioning improves engraftment

Transplantation

Volumn 77, Issue 6, 2004, Pages 819-826

  Xu, Hong ^a   Exner, Beate G ^a   Chilton, Paula M ^a   Tanner, Michael K ^a   Mueller, Yvonne M ^a   Rezzoug, Francine ^a   Ildstad, Suzanne T ^a,b  

^a UNIVERSITY OF LOUISVILLE   (United States)

^b University of Louisville School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6;

ALLOGRAFT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CONTROLLED STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MIXED LYMPHOCYTE REACTION; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; WHOLE BODY RADIATION;

ANIMALS; BONE MARROW TRANSPLANTATION; GRAFT REJECTION; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; LYMPHOCYTE CULTURE TEST, MIXED; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED STRAINS; TRANSPLANTATION CHIMERA; TRANSPLANTATION, HOMOLOGOUS; WHOLE-BODY IRRADIATION;

EID: 1842525080     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.TP.0000116414.66171.81     Document Type: Article

References (28)

1. Penn I. Why do immunosuppressed patients develop cancer. Crit Rev Oncogen 1989; 1: 27-52.
2. Platz KP, Mueller AR, Blumhardt G, et al. Nephrotoxicity after orthotopic liver transplantation in cyclosporin A and FK 506-treated patients. Transpl Int 1994; 7(Suppl 1): S52-S57.
3. Gao SZ, Schroeder JS, Hunt S, et al. Retransplantation for severe accelerated coronary disease in heart transplant recipients. Am J Cardiol 1988; 62: 876-881.
4. Ildstad ST, Sachs DH. Reconstitution with syngeneic plus allogeneic or xenogeneic bone marrow leads to specific acceptance of allografts or xenografts. Nature 1984; 307: 168-170.
5. Orloff MS, DeMara EM, Coppage ML, et al. Prevention of chronic rejection and graft arteriosclerosis by tolerance induction. Transplantation 1995; 59: 282-288.
6. Colson YL, Li H, Boggs SS, et al. Durable mixed allogeneic chimerism and tolerance by a nonlethal radiation-based cytoreductive approach. J Immunol 1996; 157: 2820-2829.
7. Mayumi H, Good RA. The necessity of both allogeneic antigens and stem cells for cyclophosphamide-induced skin allograft tolerance in mice. Transplant Proc 1988; 20: 139-141.
8. Wood ML, Gottschalk R, Monaco AP. The effect of cyclosporine on the induction of unresponsiveness in antilymphocyte serum-treated, marrow-injected mice. Transplantation 1988; 46: 449-451.
9. Cobbold SP, Martin G, Qin S, et al. Monoclonal antibodies to promote marrow engraftment and tissue graft tolerance. Nature 1986; 323: 164-166.
10. Sharabi Y, Sachs DH. Mixed chimerism and permanent specific transplantation tolerance induced by a nonlethal preparative regimen. J Exp Med 1989; 169: 493-502.
11. Colson YL, Wren SM, Schuchert MJ, et al. A nonlethal conditioning approach to achieve durable multilineage mixed chimerism and tolerance across major, minor, and hematopoietic histocompatibility barriers. J Immunol 1995; 155: 4179-4188.
12. Xu H, Exner BG, Cramer DE, et al. CD8(+), [alpha][beta]-TCR(+), and [gamma][delta]-TCR(+) cells in the recipient hematopoietic environment mediate resistance to engraftment of allogeneic donor bone marrow. J Immunol 2002; 168: 1636-1643.
13. Ricordi C, Gray DW, Hering BJ, et al. Islet isolation assessment in man and large animals. Acta Diabetol Lat 1990; 27: 185-195.
14. Hoffman RA, Langrehr JM, Billiar TR, et al. Alloantigen-induced activation of rat splenocytes is regulated by the oxidative metabolism of L-arginine. J Immunol 1990; 145: 2220.
15. Garni-Wagner BA, Purohit A, Mathew PA, et al. A novel function-associated molecule related to non-MHC-restricted cytotoxicity mediated by activated natural killer cells and T cells. J Immunol 1993; 151: 60-70.
16. Sykes M. Unusual T cell populations in adult murine bone marrow. Prevalence of CD3+CD4-CD8- and alpha beta TCR+NK1.1+ cells. J Immunol 1990; 145: 3209-3215.
17. Raziuddin A, Longo DL, Mason L, et al. Differential effects of the rejection of bone marrow allografts by the depletion of activating versus inhibiting Ly-49 natural killer cell subsets. J Immunol 1998; 160: 87-94.
18. Medawar PB. The behavior and fate of skin autografts and skin homografts in rabbits. J Anat 1944; 78: 176-199.
19. Owen RD. Immunogenetic consequences of vascular anastomoses between bovine twins. Science 1945; 102: 400-401.
20. Exner BG, Colson YL, Li H, et al. In vivo depletion of host CD4+ and CD8+ cells permits engraftment of bone marrow stem cells and tolerance induction with minimal conditioning. Surgery 1997; 122: 221-227.
21. Ildstad ST, Wren SM, Bluestone JA, et al. Characterization of mixed allogeneic chimeras: immunocompetence, in vitro reactivity and genetic specificity of tolerance. J Exp Med 1985; 162: 231-244.
22. Slavin S, Nagler A, Naparstek E, et al. Nonmyeloablative stem cell transplantation and cell therapy as an alternative to conventional bone marrow transplantation with lethal cytoreduction for the treatment of malignant and nonmalignant hematologic diseases. Blood 1998; 91: 756-763.
23. Down JD, Tarbell NJ, Thames HD, et al. Syngeneic and allogeneic bone marrow engraftment after total body irradiation: dependence on dose, dose rate, and fractionation. Blood 1991; 77: 661-669.
24. Sykes M, Chester CH, Sachs DH. Protection from graft-versus-host disease in fully allogeneic chimeras by prior administration of T cell-depleted syngeneic bone marrow. Transplantation 1988; 46: 327-330.
25. Xun CQ, Tsuchida M, Thompson JS. Delaying transplantation after total body irradiation is a simple and effective way to reduce acute graft-versus-host disease mortality after major H2 incompatible transplantation. Transplantation 1997; 64: 297-302.
26. Schots R, Kaufman L, Van Riet I, et al. Proinflammatory cytokines and their role in the development of major transplant-related complications in the early phase after allogeneic bone marrow transplantation. Leukemia 2003; 17: 1150-1156.
27. Kaufman CL, Chambers WH, Ildstad ST. Coexpression of NKR-P1 and alpha beta-TCR on lymphoid cells in fully xenogeneic (rat -gt; mouse) chimeras and syngeneically reconstituted (A -gt; A) rats. J Immunol 1993; 151: 6002-6011.
28. Cudkowicz G, Bennett M. Peculiar immunobiology of bone marrow allografts. I. Graft rejection by irradiated responder mice. J Exp Med 1971; 134: 83-102.