Carglumic acid: An advance in rare urea cycle disorders

Prescrire International

Volumn 13, Issue 69, 2004, Pages 3-4

[No Author Info available]

Author keywords

[No Author keywords available]

Indexed keywords

4 PHENYLBUTYRIC ACID; ARGININE; CARBAMIC ACID DERIVATIVE; CARGLUMIC ACID; CARNITINE; GLUTAMATE ACETYLTRANSFERASE; GLUTAMIC ACID DERIVATIVE; UNCLASSIFIED DRUG; ACYLTRANSFERASE; ARYLBUTYRIC ACID DERIVATIVE;

BODY GROWTH; BRONCHUS SECRETION; CLINICAL TRIAL; CRYING; DRUG APPROVAL; DRUG CHOICE; DRUG INDICATION; DRUG MARKETING; DRUG MECHANISM; DRUG SPECIFICITY; ENZYME DEFICIENCY; ENZYME REPLACEMENT; FRANCE; HUMAN; HYPERAMMONEMIA; HYPERTHERMIA; INTRINSIC SYMPATHOMIMETIC ACTIVITY; METABOLIC DISORDER; OPTIMAL DRUG DOSE; PSYCHOMOTOR DEVELOPMENT; REVIEW; SIDE EFFECT; SWEATING; TACHYCARDIA; TERATOGENICITY; UREA CYCLE; ARTICLE; BLOOD; CHILD; FEMALE; INBORN ERROR OF METABOLISM; MALE; RETROSPECTIVE STUDY;

ACETYLTRANSFERASES; CHILD; DRUG APPROVAL; FEMALE; FRANCE; GLUTAMATES; HUMANS; HYPERAMMONEMIA; MALE; METABOLISM, INBORN ERRORS; PHENYLBUTYRATES; RETROSPECTIVE STUDIES;

EID: 1842505453     PISSN: 11677422     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (9)

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2. Guffon N "Expert report on the clinical documentation of the medicinal product Carbaglu° 200 mg, dispersible tablets (N-carbamoyl L-glutamic acid [Carglumic acid p INN)" 1 October 2001: 23 pages.
3. Prescrire Editorial Staff "Sodium phenylbutyrate in urea synthesis disorders due to enzyme deficiency" Prescrire Int 2001; 10:s (53): 95.
4. Bachmann C et al. "N-acetyglutamate synthetase (NAGS) deficiency: diagnosis, clinical observations and treatment" Adv Experiment Med Biol 1982; 153: 39-45.
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8. Schubiger G et al. "N-acetylglutamate synthetase deficiency: diagnosis management and follow-up of a rare disorder of ammonia detoxication" Eur J Pediatr 1991; 150: 353-356.
9. The European Agency for the Evaluation of Medicinal Products - Committee for Proprietary Medicinal Products "European Public Assessment Report "Carbaglu"" 13 February 2003; 42 pages.