Effect of an antiasthmatic ayurvedic drug PulmoFlex on biosynthesis of leukotrienes in neutrophils and paf induced platelet aggregation

Phytomedica

Volumn 2, Issue 1-2, 2001, Pages 103-109

  Gabrielian, E S ^a   Narimanian, M Z ^b   Aslanian, G ^a   Amroyan, E A ^a   Wagner, H ^c   Panossian, A G ^a  

^a Guelbenkian Research Laboratory   (Armenia)

^b Department of Respiratory Diseases   (Armenia)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

12 HYDROXYICOSATETRAENOIC ACID; 15 HYDROXYICOSATETRAENOIC ACID; 5 HYDROXYICOSATETRAENOIC ACID; ADHATODA VASICA EXTRACT; ALBEZZIA LEBBEK EXTRACT; ALPINIA GALANGA EXTRACT; ANTIASTHMATIC AGENT; ARACHIDONATE 15 LIPOXYGENASE; ARACHIDONATE 5 LIPOXYGENASE; ARACHIDONIC ACID; AYURVEDIC DRUG; GINGER EXTRACT; GLYCYRRHETINIC ACID; GLYCYRRHIZA GLABRA EXTRACT; HEDYCHIUM SPICATUM EXTRACT; HERBACEOUS AGENT; ICOSANOID; LEUKOTRIENE; LEUKOTRIENE B4 DERIVATIVE; OCIMUM SANCTUM EXTRACT; PIPER LONGUM EXTRACT; PLANT EXTRACT; PROSTAGLANDIN SYNTHASE; PULMOFLEX; SAUSSUREA LAPPA EXTRACT; SOLANUM XANTHOCARPUM EXTRACT; THROMBOCYTE ACTIVATING FACTOR; UNCLASSIFIED DRUG; VASICINE;

ADHATODA; ADHATODA VASICA; ALBEZZIA LEBBEK; ARACHIDONIC ACID METABOLISM; ARTICLE; ASTHMA; BIOSYNTHESIS; CELL ISOLATION; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG INHIBITION; DRUG MECHANISM; EXPERIMENTATION; GRANULOCYTE; HEDYCHIUM SPICATUM; HUMAN; HUMAN CELL; MODULATION; NEUTROPHIL; PIPER LONGUM; PIPERACEAE; PLANT; SOLANUM; SOLANUM XANTHOCARPUM; THROMBOCYTE AGGREGATION;

EID: 1842505171     PISSN: 09723293     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Boyum, A.(1987) Scand. J. Immunol 5: 9.
2. Braquet, P.G., Spinnewyn, B., Braquet. M., Bougain, P.H., Taylor, J.E., Etienne, A.,and Drien, K. (1985). Blood Vessel 16: 558.
3. Braquet, P.G., Etienne, A., Tonvay, C., Bourgain, R.H., Lefort, J., Vargaftig, B.B. (1985) Lancet 1: 1501.
4. Bray, M.A., Ford-Hutchinson, A.W., and Smith, M.J.H.(1981) Prostaglandins 22, 313.
5. Chauhan, S. and Agrawala,S.(1999) Indian Drugs 36: 368.
6. Claesson, H.E., Jakobsson, P.J., Steihilber, D., Odlander, B. and Samuelsson, B. (1993) J. Lipid Mediators 6, 15.
7. Dahlet, S.E., Bjork, J., Hedqvist, P. and Samuelsson, B. (1991) Proc Natl. Acad. Sci. USA 78, 3887.
8. DeFeudis, F.V.: Ginkgo biloba Extract (EGB 761): Pharmacological activities and clinical applications. Elsevier, Amsterdam, London, Paris, New York, Tokio (1991).
9. Iwasaki, E.(1989) Acta Paedit.Jpn 31: 725.
10. Morley, J.S. Sanjar, S. and Page, C.P.(1984) Lancet II: 1142.
11. Nakamura, T., Kuriyama, M., Kosuge, E., Ishihara, K. and Ito K. (1993): Effects o Saiboku-to (TJ-96) on the production of platelet-activating factor in human neutrophils. In: Immunomodulating Drugs. Annals New York Acad.Sci., 685: 572
12. Nakamura, T.Y., Morita, Y., Kuriyama, M., Ishihara, K., Ito, K., and Miyamoto (1987) Int.Arch.Allergy Appl.Immunol 82: 57.
13. O'Byrne, P.M.(1994) Eicasanoids and asthma. Ann. New York Acad. Sci. 744, 251-261.
14. O'Flaherty, J.T., and Wykle, R.T.(1983): Clin Rev. Allergy 1: 357
15. Page, C.P., Archer, C.B, Paul, W. and Morley, J.(1984) TIPS III: 239.
16. Pinckard, R.N. Ludwig J.C. and MeManus, LM (1988).Platelet-Activating Factors. In: Inflammation. Basic principles and clinical correlates. Eds. J.I. Gallin, I.M. Goldstein, R.Snyderman. Raven Press, New York, 139.
17. Piper, P.J.(1984) Physiol.Rev 64: 744.
18. Sampson, A.P(1996) Clinical and Exp.Allergy 26: 995.
19. Samuelson, B., Dahlen, S.E. and Lindgren, J.A. (1987) Sciences 237: 117.
20. Sasagawa, M., Satoh, T., Takemoto, A., Hasegawa, T.and Suzuki, E. (1994) Arakawa M: Arerugi 43: 28.
21. Serhan, C.N. Radin A, Smolen, J.E. Korchak, H., Samuelsson, B.and Weissmann, G. Biochem. Biophys. Res. Commun 107: 1006.