Modelling the pituitary response to luteinizing hormone-releasing hormone

Journal of Neuroendocrinology

Volumn 16, Issue 3, 2004, Pages 265-271

  Scullion, S ^a   Brown, D ^b   Leng, Gareth ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b BABRAHAM INSTITUTE   (United Kingdom)

Author keywords

Luteinizing hormone surge; Luteinizing hormone releasing hormone; Modelling; Pituitary; Priming

Indexed keywords

GONADORELIN; LUTEINIZING HORMONE; STEROID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCULATION; COMPUTER SIMULATION; CONTROLLED STUDY; FEMALE; HORMONE BLOOD LEVEL; HORMONE RESPONSE; HYPOPHYSIS FUNCTION; IN VITRO STUDY; IN VIVO STUDY; LUTEINIZING HORMONE BLOOD LEVEL; LUTEINIZING HORMONE RELEASE; NONHUMAN; OVULATION; PRIORITY JOURNAL; PULSE GENERATOR; RAT; REPRODUCTION; SIMULATION;

ANIMALS; ESTROUS CYCLE; FEMALE; GONADOTROPIN-RELEASING HORMONE; LUTEINIZING HORMONE; MODELS, BIOLOGICAL; PERIODICITY; PITUITARY GLAND; RATS;

EID: 1842485018     PISSN: 09538194     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0953-8194.2004.01169.x     Document Type: Article

References (22)

1. Hillier SG, Whitelaw PF, Smyth CD. Follicular oestrogen synthesis: The 'two-cell, two-gonadotrophin' model revisited. Mol Cell Endocrinol 1994; 100: 51-54.
2. Fox SR, Smith MS. Changes in the pulsatile pattern of luteinizing hormone secretion during the rat estrous cycle. Endocrinology 1985; 116: 1485-1492.
3. Blake CA. A detailed characterization of the proestrous luteinizing hormone surge. Endocrinology 1976; 98: 445-450.
4. Veldhuis JD, Johnson ML, Gallo RV. Reanalysis of the rat proestrous LH surge by deconvolution analysis. Am J Physiol 1993; 265: R240-R245.
5. Aiyer MS, Chiappa SA, Fink G. A priming effect of luteinizing hormone releasing factor on the anterior pituitary gland in the female rat. J Endocrinol 1974; 62: 573-588.
6. Apfelbaum ME. Basal and GnRH-induced release and synthesis of LH and FSH from incubated pituitary glands throughout the 4-day estrous cycle of the rat. Horm Res 1981; 15: 109-121.
7. Mobbs C, Fink G, Johnson M, Welch W, Pfaff D. Similarity of an estrogen-induced protein and a luteinizing hormone releasing hormone-induced protein. Mol Cell Endocrinol 1989; 62: 297-306.
8. Waring DW, Turgeon JL. Luteinizing hormone-releasing hormone-induced luteinizing hormone secretion in vitro: Cyclic changes in responsiveness and self-priming. Endocrinology 1980; 106: 1430-1436.
9. Aiyer MS, Fink G, Greig F. Sensitivity of the anterior pituitary gland to luteinizing hormone releasing factor (LRF) during pro-oestrus in the rat. J Physiol 1973; 231: 32P-34P.
10. Byrne B, Fowler PA, Templeton A. Role of progesterone and nonsteroidal ovarian factors in regulating gonadotropin-releasing hormone self-priming in vitro. J Clin Endocrinol Metab 1996; 81: 1454-1459.
11. Waring DW, Turgeon JL. LHRH self priming of gonadotrophin secretion: Time course of development. Am J Physiol 1983; 244: C410-C418.
12. Fink G, Chiappa SA, Aiyer MS. Priming effect of luteinizing hormone releasing factor elicited by preoptic stimulation and by intravenous infusion and multiple injections of the synthetic decapeptide. J Endocrinol 1976; 69: 359-372.
13. 2+ and cyclic AMP. J Endocrinol 1979; 81: 223-234.
14. Curtis A, Lyons V, Fink G. The priming effect of LH-releasing hormone: Effects of cold and involvement of new protein synthesis. J Endocrinol 1985; 105: 163-168.
15. Stojilkovic SS, Reinhart J, Catt KJ. Gonadotropin-releasing hormone receptors: Structure and signal transduction pathways. Endocr Rev 1994; 15: 462-499.
16. Mitchell R, Johnson M, Ogier SA, Fink G. Facilitated calcium mobilization and inositol phosphate production in the priming effect of LH-releasing hormone in the rat. J Endocrinol 1988; 119: 293-301.
17. Lewis CE, Morris JF, Fink G. The role of microfilaments in the priming effect of LH-releasing hormone: An ultrastructural study using cytochalasin B. J Endocrinol 1985; 106: 211-218.
18. Brown D, Herbison AE, Robinson JE, Marrs RW, Leng G. Modelling the luteinizing hormone-releasing hormone pulse generator. Neuroscience 1994; 63: 869-879.
19. Brown D, Stephens EA, Leng G, Smith RG. Mathematical models of GH release from the pituitary. In: Smith RG, Thorner MO, eds. Human Growth Hormone: Research and Clinical Practice. Totowa, NJ: Humana Press, 2000: 119-130.
20. Scullion S, Brown D, Leng G. A model of LHRH 'self-priming' at the pituitary. In: Holcome M, Paton R, eds. Information Processing in Cells and Tissues. New York: Plenum Press, 1998: 151-160.
21. Kalra PS, Kalra SP. Temporal changes in the hypothalamic and serum luteinizing hormone-releasing hormone (LH-RH) levels and the circulating ovarian steroids during the rat oestrous cycle. Acta Endocrinologica 1977; 85: 449-455.
22. Goldbeter A. Biochemical Oscillations and Cellular Rhythms: The Molecular Bases of Periodic and Chaotic Behaviour. Cambridge: Cambridge University Press, 1997.