Testing the Bioavailability of Oral L-Thyroxine by Studying Its Absorption: Smoke or Mirrors?

Thyroid

Volumn 14, Issue 3, 2004, Pages 167-168

  Stockigt, Jim ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

LEVOTHYROXINE;

DOSE RESPONSE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG FORMULATION; EDITORIAL; HUMAN; HYPOTHYROIDISM; PRIORITY JOURNAL; SIDE EFFECT;

ABSORPTION; ADMINISTRATION, ORAL; BIOLOGICAL AVAILABILITY; HUMANS; HYPOTHYROIDISM; THYROXINE;

EID: 1842482345     PISSN: 10507256     EISSN: None     Source Type: Journal    
DOI: 10.1089/105072504773297821     Document Type: Editorial

References (11)

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2. Wartofsky L 1997 Bioequivalence of levothyroxine preparations: shortcomings and implications of a recently published study. The Endocrinologist 7:322-333.
3. Rennie D 1997 Thyroid storm. JAMA 277:1238-1243.
4. Various authors 1997 JAMA 278:895-900.
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8. Blakesley V, Awni W, Locke C et al. 2004 Are bioequivalence studies of levothyroxine sodium formulations in euthyroid volunteers reliable? Thyroid, 14:189-198.
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10. Fish LH, Schwartz HL, Cavanaugh J, Steffes MW, Bantle JP, Oppenheimer JH 1987 Replacement dose, metabolism, and bioavailability of levothyroxine in the treatment of hypothyroidism. Role of triiodothyronine in pituitary feedback in humans. N Engl J Med 316:764-770.
11. Spencer CA, LoPresti JS, Nicoloff JT, Dlott R, Schwarzbein D 1995 Multiphasic thyrotropin responses to thyroid hormone administration in man. J Clin Endocrinol Metab 80:854-859.