Comparison of the immune response to a self antigen after DNA immunisation of HLA*A201/H-2Kb and HHD transgenic mice

Vaccine

Volumn 22, Issue 13-14, 2004, Pages 1728-1731

  Ramage, Judith M ^a   Metheringham, Rachael ^a   Moss, Robert ^a   Spendlove, Ian ^a   Rees, Robert ^b   Durrant, Lindy G ^a  

^a NOTTINGHAM CITY HOSPITAL   (United Kingdom)

^b NOTTINGHAM TRENT UNIVERSITY   (United Kingdom)

Author keywords

0201; Cytotoxic lymphocytes; HLA A; Transgenic mice

Indexed keywords

AUTOANTIGEN; CD8 ANTIGEN; DNA VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN RECOGNITION; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DNA IMMUNIZATION; FEMALE; IMMUNE RESPONSE; IMMUNIZATION; MALE; MOLECULAR DYNAMICS; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; RAT; TRANSGENIC MOUSE;

ANIMALS; AUTOANTIGENS; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE; CHROMIUM RADIOISOTOPES; EPITOPES; HLA-A ANTIGENS; HUMANS; MICE; MICE, TRANSGENIC; T-LYMPHOCYTES, CYTOTOXIC; VACCINES, DNA;

EID: 1842479785     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2004.01.034     Document Type: Article

References (7)

1. Irwin M.J., Heath W.R., Sherman L.A. Species-restricted interactions between CD8 and the alpha 3 domain of class I influence the magnitude of the xenogeneneic response. J. Exp. Med. 170:1989;1091.
2. Kalinke U., Arnold B., Hammerling G. Strong xenogeneic HLA response in transgenic mice after introducing an α3 domain into HLA-b27. Nature. 348:1990;642.
3. Vitiello A., Marchesini D., Furze J., Sherman L.A., Chesnut R.W. Analysis of the HLA-restricted influenza-specific cytotoxic T lymphocyte response in transgenic mice carrying a chimeric human-mouse class I major histocompatibility complex. J. Exp. Med. 173:1991;1007.
4. Pascolo S., Bervas N., Ure J.M., Smith A.G., Lemonnier F.A., Perarnau B. HLA-A2.1-restricted education and cytolytic activity of CD8+ T lymphocyte from β2 microglobulin (β2m) HLA-A2.1 monochain transgenic H-2Db β2m double knockout mice. J. Exp. Med. 185(12):1997;2043-2051.
5. Firat H., Cochet M., Rohrlich P.-S., Garcia-Pons F., Darche S., Danos O.et al. Comparative analysis of the CD8+ T cell repertoires of H-2 class I wild-type/HLA-A2.1 and H-2 class I knockour/HLA-A2.1 transgenic mice. Int. Immunol. 14(8):2002;925-934.
6. Firat H., Garcia-Pons F., Tourdot S., Pascolos S., Scardino A., Garcia Z.et al. HLA-A2.1-transgenic mice: a versatile animal model for preclincal evaluation of antitumor immunotherapeutic strategies. Eur. J. Imunol. 29:1999;3112-3121.
7. Epstein H., Hardy R., May J.S., Johnston M.H., Holmes N. Expression and function of HLA-A2.1 in transgenic mice. Eur. J. Immunol. 19:1989;1575-1583.