Hypoxic Stop-Flow Perfusion with Mitomycin-C in the Treatment of Multifocal Liver Metastases. Usefulness of a Vascular Arterial Stent to Prevent Iatrogenic Lesions of the Hepatic Arterial Wall

Journal of Experimental and Clinical Cancer Research

Volumn 22, Issue 4 SUPPL., 2003, Pages 203-206

  Gadaleta, Cosmo D ^a   Catino, A ^a   Ranieri, G ^a   Armenise, F ^a   Console, G ^a   Mattioli, V ^a  

^a NATIONAL CANCER INSTITUTE GIOVANNI PAOLO II   (Italy)

Author keywords

Hepatic stop flow intra arterial chemotherapy; Liver metastases

Indexed keywords

GELATIN SPONGE; MITOMYCIN C;

ABDOMINAL PAIN; ADULT; AGED; ANEMIA; ARTERY LESION; ARTIFICIAL EMBOLISM; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG CYTOTOXICITY; FEMALE; FEVER; FOLLOW UP; HEPATIC ARTERY; HUMAN; HYPOXIA; IATROGENIC DISEASE; LIVER METASTASIS; LIVER PERFUSION; MALE; NAUSEA; PRIORITY JOURNAL; SOLID TUMOR; STENT; THROMBOCYTOPENIA; VOMITING;

ADULT; AGED; ANOXIA; ANTIBIOTICS, ANTINEOPLASTIC; BALLOON OCCLUSION; CHEMOTHERAPY, CANCER, REGIONAL PERFUSION; FEMALE; HEPATIC ARTERY; HUMANS; IATROGENIC DISEASE; INFUSIONS, INTRA-ARTERIAL; LIVER NEOPLASMS; MALE; MIDDLE AGED; MITOMYCIN; STENTS;

EID: 1842477962     PISSN: 03929078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (14)

1. Tellez C., Benson III A.B., Lyster M.T. et al.: Phase II trial of chemoembolization for the treatment of metastatic colorectal carcinoma to the liver and review of the literature. Cancer 82:1250-1259, 1998.
2. Breedis C., Young G.: Blood supply of neoplasms of the liver. Am J Pathol 30:969-985, 1954.
3. Fiorentini G., Poddie D.B., De Giorgi U. et al.: Global approach to hepatic metastases from colorectal cancer: Indication and outcome of intra-arterial chemotherapy and other hepatic-directed treatments. In: Medical Oncology, Macmillan Publishers Ltd. 17:163-173, 2000.
4. Theicher B.A., Lazo J.S., Sartorelli A.C. Classification of antineoplastic agents by their selective toxicities toward oxygenated and hypoxic tumor cells. Cancer 41:73-76, 1981.
5. Aigner K.R., Kaevel K.: Pelvic stop flow infusion (PSI) and hypoxic pelvic perfusion (HPP) with mitomycin and melphalan for recurrent rectal cancer. Reg. Cancer Treat. 1:6-11, 1994.
6. Cantore M., Fiorentini G., Riitano G. et al.: Hypoxic abdominal perfusion (HAP): rationale and evaluation of a new technique. Reg. Cancer Treat. 4:161-165, 1994.
7. Roversi R., Cavallo G., Ricci S., Rossi G., Roversi M., Fiorentini G.: Hypoxic stop-flow liver perfusion: preliminary results in the treatment of multiple hepatic metastases. Radiol. Med. 93:410-417, 1997.
8. Aigner K.R., Gailhofer S.: Celiac axis infusion (MMC, CDDP, 5-FU) and aortic stop-flow infusion vs. abdominal hypoxic perfusion (MMC) in UICC stage III-IV pancreatic cancer-48 patients. Reg. Cancer Treat. 6, suppl 1:3, 1993.
9. Dazzi C., Fiorentini G., Davitti B. et al.: High-dose intra-arterial plus intraperitoneal chemotherapy combined with hemofiltration in liver metastases from colorectal cancer. Tumori 80:204-208, 1994.
10. Kameyama M., Imaoka S., Fukuda I. et al.: Delayed washout of intratumor blood flow is associated with good response to intraarterial chemoembolization for liver metastases of colorectal cancer. Surgery 114:97-101, 1993.
11. Sone Y., Arai Y., Mukaijo T. et al.: Changes of arterial blood flow patterns by patients' posture during hepatic arterial infusion chemotherapy assessed by (99m)Tc-MAA perfusion scintigraphy. Kakuigaku 30/11:1353-1358, 1993.
12. Wallace S., Carrasco C.H., Chamsangavej C. et al.: Hepatic artery infusion and chemoembolization in the management of liver metastases. Cardiovasc Intervent Radiol 13:153-160, 1990.
13. Kemeny N., Fata F.: Hepatic-arterial chemotherapy. Lancet Oncol 2:418-428, 2001.
14. Fiorentini G., Davitti B., Poddie D. et al.: Hepatic arterial infusion (HAI) of high dose chemotherapy plus caval chemofiltration vs HAI of prolonged low doses in patients with liver metastases from colorectal carcinoma: results of a prospective randomized trial.Reg. Cancer Treat. 7:165-168, 1994.