Successful resuscitation of a verapamil intoxicated child with a dextrose-insulin infusion

Clinical Intensive Care

Volumn 14, Issue 3-4, 2003, Pages 109-113

  Meyer, M T ^a   Stremski, E ^a,b   Scanlon, M C ^a,c  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b Wisconsin Poison Center ^*  (United States)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED CARBON; ADRENALIN; CALCIUM CHLORIDE; DOPAMINE; GLUCAGON; GLUCOSE; HYPERTENSIVE AGENT; INSULIN; NORADRENALIN; SODIUM CHLORIDE; SORBITOL; VERAPAMIL;

ADOLESCENT; ARTICLE; ATRIOVENTRICULAR BLOCK; ATRIOVENTRICULAR DISSOCIATION; BRADYCARDIA; CASE REPORT; DEPRESSION; DISEASE COURSE; DISTRIBUTION VOLUME; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG INFUSION; DRUG METABOLISM; DRUG OVERDOSE; ENDOTRACHEAL INTUBATION; EXTUBATION; FEMALE; FOLLOW UP; GLUCOSE BLOOD LEVEL; HEMODYNAMICS; HUMAN; HYPOTENSION; MIGRAINE; POSTTRAUMATIC STRESS DISORDER; RESUSCITATION; SINUS RHYTHM; SOMNOLENCE; STOMACH LAVAGE; SUICIDE ATTEMPT; SUSTAINED RELEASE FORMULATION;

EID: 1842472115     PISSN: 09563075     EISSN: None     Source Type: Journal    
DOI: 10.1080/09563070310001643183     Document Type: Article

References (15)

1. Tom P, Morrow C, Kelen G. Delayed hypotension after overdose of sustained release verapamil. J Emerg Med 1994; 12: 621-5.
2. Ramoska E, Spiller H, Myers A. Calcium channel blocker toxicity. Ann Emerg Med 1990; 19: 649-53.
3. Lip G, Ferner R. Poisoning with anti-hypertensive drugs: calcium antagonists. J Hum Hypertens 1995; 9: 155-61.
4. Horowitz B, Rhee K. Massive verapamil ingestion: A report of two cases and a review of the literature. Am J Emerg Med 1989; 7: 624-31.
5. Kline J, Tomaszewski C, Schroeder J, Raymond R. Insulin is a superior antidote for cardiovascular toxicity induced by verapamil in the anesthetized canine. J Pharmacol Exp Ther 1993; 267: 744-50.
6. Yuan T, Kerns W, Tomaszewski C, Ford M, Kline J. Insulin-glucose as adjunctive therapy for severe calcium channel antagonist poisoning. J Toxicol Clin Toxicol 1999; 37: 463-74.
7. Fleckenstein A. Specific pharmacology of calcium in myocardium, cardiac pacemakers, and vascular smooth muscle. Annu Rev Pharmacol Toxicol 1977; 17: 149-66.
8. Hofer C, Smith J, Tenholder M. Verapamil intoxication: A literature review of overdoses and discussion of therapeutic options. Am J Med 1993; 95: 431-8.
9. Follath F, Ha H, Schutz E. F B. Pharmacokinetics of conventional and slow-release verapamil. Br J Clin Pharmacol 1986; 21: 149-53S.
10. Oe H, Taniura T, Ohgitani N. A case of severe verapamil overdose. Jpn Circ J 1998; 62: 72-6.
11. MacDonald D, Alguire P. Case report: Fatal overdose with sustained-release verapamil. Am J Med Sci 1992; 303: 115-17.
12. Tanen D, Ruha A, Curry S, Graeme K, Reagan C. Hypertonic sodium bicarbonate is effective in the acute management of verapamil toxicity in a swine model. Ann Emerg Med 2000; 36: 547-53.
13. Kline J, Leonova E, Raymond R. Beneficial myocardial metabolic effects of insulin during verapamil toxicity in the anesthetized canine. Crit Care Med 1995; 23: 1251-63.
14. Kline J, Raymond R, Leonova E, Williams T, Watts J. Insulin improves heart function and metabolism during non-ischemic cardiogenic shock in awake canines. Cardiovasc Res 1997; 34: 289-98.
15. Boyer E, Shannon M. Treatment of calcium-channel-blocker intoxication with insulin infusion. N Engl J Med 2001; 344: 1721-22.