NADPH oxidase activity of neutrophil specific granules: Requirements for cytosolic components and evidence of assembly during cell activation

Molecular Genetics and Metabolism

Volumn 81, Issue 4, 2004, Pages 313-321

  Ambruso, Daniel R ^a   Cusack, Nancy ^a   Thurman, Gail ^a  

^a Children's Hospital Colorado   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P47; PROTEIN P67; RAC PROTEIN; RECOMBINANT PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ARTICLE; CELL ACTIVATION; CELL FREE SYSTEM; CELL MEMBRANE; CELL STIMULATION; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVATION; ENZYME ACTIVITY; EVALUATION; HUMAN; HUMAN CELL; MICROBIAL ACTIVITY; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; SECRETORY GRANULE;

CELL MEMBRANE; CYTOCHROMES C; CYTOPLASMIC GRANULES; CYTOSOL; ENZYME ACTIVATION; HUMANS; NADPH OXIDASE; NEUTROPHILS; RECOMBINANT PROTEINS; SUPEROXIDE DISMUTASE; TRANSLOCATION, GENETIC;

EID: 1842471238     PISSN: 10967192     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymgme.2004.01.009     Document Type: Article

References (22)

1. Leto T.L. Gallin J.I., Snyderman R. Inflammation Basic Principles and Clinical Correlates. 1999;769-787 Lippincott Williams and Watkins, Philadelphia.
2. Ambruso D.R., Johnston R.B. Jr. Chronic granulomatous disease of childhood. Chernick V., Boat T.F. Kendig's Disorders of the Respiratory Tract in Children. 1998;WB Saunders Co, London.
3. 2 activity and enhances superoxide anion production by a cell-free system of NADPH oxidase activity. J. Biol. Chem. 277:2002;45181-45187 doi:10.1074/jbc.M202869200.
4. 2 oxidoreductase in human neutrophils after stimulation with phorbol myristate acetate. J. Biol. Chem. 265:1990;924-930.
5. Clark R.A., Volpp B.D., Leidal K.G., Nauseef W.M. Two cytosolic components of the human neutrophil respiratory burst oxidase translocate to the plasma membrane during cell activation. J. Clin. Invest. 85:1990;714-721.
6. Ambruso D.R., Knall C., Abell A.N., Panepinto J., Kurkchubasche A., Thurman G., Gonzalez-Aller C., Hiester A., deBoer M., Harbeck R.J., Oyer R., Johnson G.L., Roos D. Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation. Proc. Natl. Acad. Sci. USA. 97:2000;4654-4659 doi:10.1073/pnas.080074897.
7. Kurkchubasche A.G., Panepinto J.A., Tracy T.F. Jr., Thurman G.W., Ambruso D.R. Clinical features of a human Rac2 mutation: a complex neutrophil dysfunction disease. J. Pediatr. 139:2001;141-147 doi:10.1067/mpd.2001.114718.
8. Ambruso D.R., Sasada M., Nishiyama H., Kubo A., Komiyama A., Allen R.H. Defective bactericidal activity and absence of specific granules of neutrophils from a patient with recurrent bacterial infections. J. Clin. Immunol. 4:1984;23-30.
9. Gallin J.I. Neutrophil specific granule deficiency. Ann. Rev. Med. 36:1985;263-274.
10. Lekstrom-Himes J.A., Dorman S.E., Kopar P., Holland S.M., Gallin J.I. Neutrophil-specific granule deficiency results from a novel mutation with loss of function of the transcription factor CCAAT/enhancer binding protein epsilon. J. Exp. Med. 189:1999;1847-1852.
11. Gombart A.F., Kwok S.H., Anderson K.L., Yamaguchi Y., Torbett B.E., Koeffler H.P. Regulation of neutrophil and eosinophil secondary granule gene expression by transcription factors C/EBP epsilon and PU.1. Blood. 101:2003;3265-3273.
12. Rosenthal J., Thurman G.W., Cusack N., Peterson V.M., Malech H.L., Ambruso D.R. Neutrophils from patients after burn injury express a deficiency of the oxidase components p47-phox and p67-phox. Blood. 88:1996;4321-4329.
13. Leavey P.J., Sellins K.S., Thurman G., Elzi D., Hiester A., Silliman C.C., Zerbe G., Cohen J.J., Ambruso D.R. In vivo treatment with granulocyte colony stimulating factor (G-CSF) results in divergent effects on neutrophil functions measured in vitro. Blood. 92(11):1998;4366-4374.
14. Bjerrum O.W., Borregaard N. Mixed enzyme-linked immunosorbent assay (MELISA) for HLA class I antigen: a plasma membrane marker. Scand. J. Immunol. 31:1990;305-313.
15. ′ -O-(3-thio) triphosphate J. Biol. Chem. 265:1990;15782-15787.
16. Bjerrum O.W., Borregaard N. Dual granule localization of the dormant NADPH oxidase and cytochrome b559 in human neutrophils. Eur. J. Haematol. 43:1989;67-77.
17. Borregaard N., Heiple J.M., Simons E.R., Clark R.A. Subcellular localization of the b cytochrome component of the human neutrophil microbicidal oxidase: translocation during activation. J. Cell Biol. 97:1983;52-61.
18. Curnutte J.T., Kuver R., Scott P. Activation of neutrophil NADPH oxidase in a cell-free system: partial purification of components and characterization of the activation process. J. Biol. Chem. 262:1987;5563-5569.
19. Vaissiere C., Le Cabec V. Maridonneau-Parini I. NADPH oxidase is functionally assembled in specific granules during activation of human neutrophils. J. Leukoc. Biol. 65:1999;629-634.
20. Gallin J.I., Fletcher M.P., Seligmann B.E., Hoffstein S., Cehrs K., Mounessa N. Human neutrophil-specific granule deficiency: a model to assess the role of neutrophil-specific granules in the evolution of the inflammatory response. Blood. 59:1982;1317-1329.
21. Ambruso D.R., Sasada M., Nishiyama H., Kubo A., Komiyama A., Allen R.H. Defective bactericidal activity and absence of specific granules in neutrophils from a patient with recurrent bacterial infections. J. Clin. Immunol. 4:1984;23-30.
22. Ambruso D.R., Stork L.C., Gibson B.E., Thurman G.W. Increased activity of the respiratory burst in cord blood neutrophils: kinetics of the NADPH oxidase enzyme system in subcellular fractions. Pediatr. Res. 21:1987;205-210.