Bioassay-directed chemical analysis utilizing LC-MS: A tool for identifying estrogenic compounds in water samples?

Analytical and Bioanalytical Chemistry

Volumn 378, Issue 3, 2004, Pages 709-715

  Heisterkamp, Inga ^a,b   Gandrass, Juergen ^a   Ruck, Wolfgang ^b  

^a INSTITUTE OF MATERIALS RESEARCH   (Germany)

^b LEUPHANA UNIVERSITY OF LÜNEBURG   (Germany)

Author keywords

Bioassay directed chemical analysis; Estrogenic activity; LC MS MS; Liquid liquid extraction; Saccharomyces cerevisiae; Sewage treatment plant effluent

Indexed keywords

EFFLUENTS; HORMONES; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; SEWAGE TREATMENT PLANTS; SIZE EXCLUSION CHROMATOGRAPHY; SOLVENT EXTRACTION; WATER ANALYSIS; YEAST;

BIOASSAY-DIRECTED CHEMICAL ANALYSIS; ESTROGENIC ACTIVITY; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY-MASS SPECTROMETRY (LC-MS-MS); LIQUID-LIQUID EXTRACTION; SACCHAROMYCES CEREVISIAE; SEWAGE-TREATMENT PLANT EFFLUENT;

BIOASSAY;

SACCHAROMYCES CEREVISIAE;

ESTROGEN;

ARTICLE; BIOASSAY; ELECTROSPRAY MASS SPECTROMETRY; GEL CHROMATOGRAPHY; GENETIC RECOMBINATION; GENETICS; METHODOLOGY; SACCHAROMYCES CEREVISIAE; SENSITIVITY AND SPECIFICITY; WATER POLLUTANT;

BIOLOGICAL ASSAY; CHROMATOGRAPHY, GEL; ESTROGENS, NON-STEROIDAL; RECOMBINATION, GENETIC; SACCHAROMYCES CEREVISIAE; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; WATER POLLUTANTS, CHEMICAL;

EID: 1842463404     PISSN: 16182642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00216-003-2380-5     Document Type: Article

References (25)

1. Purdom CE, Hardiman PA, Bye VJ, Eno NC, Tyler CR, Sumpter JP (1994) Chem Ecol 8:275-285
2. Tilton F, Benson WH, Schlenk D (2002) Aquat Toxicol 61:211-224
3. Körner W, Spengler P, Bolz U, Schuller W, Hanf V, Metzger JW (2001) Environ Toxicol Chem 20:2142-2151
4. Snyder SA, Villeneuve DL, Snyder EM, Giesy JP (2001) Environ Sci Technol 35:3620-3625
5. Thomas KV, Hurst MR, Matthiessen P, Waldock MJ (2001) Environ Toxicol Chem 20:2165-2170
6. Legler J, Leonards P, Spenkelink A, Murk AJ (2003) Ecotoxicology 12:239-249
7. Schuetzle D, Lewtas J (1986) Anal Chem 58:1060A-1075A
8. Mount DI, Anderson-Carnahan L (1988) EPA/600/3-88-34. US Environmental Protection Agency
9. Mount DI, Anderson-Carnahan L (1988) EPA/600/3-88-35. US Environmental Protection Agency
10. Mount DI, Anderson-Carnahan L (1988) EPA/600/3-88-36. US Environmental Protection Agency
11. Sheahan DA, Brighty GC, Daniel M, Kirby SJ, Hurst MR, Kennedy J, Morris S, Routledge EJ, Sumpter JP, Waldock MJ (2002) Environ Toxicol Chem 21:507-514
12. Desbrow C, Routledge EJ, Brighty GC, Sumpter JP, Waldock M (1998) Environ Sci Technol 32:1549-1558
13. López de Alda MJ, Barceló D (2001) Fresenius J Anal Chem 371:437-447
14. Baronti C, Curini R, D'Ascenzo G, Di Corcia A, Gentili A, Samperi R (2000) Environ Sci Technol 34:5059-5066
15. Croley TR, Hughes RJ, Koenig BG, Metcalfe CD, March RE (2000) Rapid Commun Mass Spectrom 14:1087-1093
16. López de Alda MJ, Barceló D (2001) J Chromatogr A 938: 145-153
17. Solé M, López de Alda MJ, Castillo M, Porte C, Ladegaard-Pedersen K, Barceló D (2000) Environ Sci Technol 34:5076-5083
18. Johnson AC, Belfroid A, Di Corcia A (2000) Sci Total Environ, 256:163-173
19. Adler P, Steger-Hartmann T, Kalbfus W (2001) Acta Hydrochim Hydrobiol 29:227-241
20. Laganà A, Bacaloni A, Fago G, Marino A (2000) Rapid Commun Mass Spectrom 14:401-407
21. Routledge EJ, Sumpter JP (1996) Environ Toxicol Chem 15:241-248
22. Körner W, Bolz U, Sïßmuth W, Hiller G, Schuller W, Hanf V, Hagenmaier H (2000) Chemosphere 40:1131-1142
23. Spengler P, Körner W, Metzger JW (1999) Vom Wasser 93:141-157
24. Spengler P, Körner W, Metzger JW (2001) Environ Toxicol Chem 20:2133-2141
25. Kuch HM, Ballschmiter K (2000) Fresenius J Anal Chem 366: 392-395