-
1
-
-
0032766426
-
Lovastatin augments apoptosis induced by chemotherapeutic agents in colon cancer cells
-
Agarwal B., Bhendwal S., Halmos B., Moss S. F., Ramey W. G. and Holt P. R. (1999) Lovastatin augments apoptosis induced by chemotherapeutic agents in colon cancer cells. Clin. Cancer Res. 5, 2223-2229.
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 2223-2229
-
-
Agarwal, B.1
Bhendwal, S.2
Halmos, B.3
Moss, S.F.4
Ramey, W.G.5
Holt, P.R.6
-
2
-
-
0033607506
-
Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte hemoeostasis, and to preclude autoimmunity
-
Bouillet P., Metcalf D., Huang D. C. S., Tarlinton D. M., Kay T. W. H., Kontgen F., Adams J. M. and Strasser A. (1999) Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte hemoeostasis, and to preclude autoimmunity. Science 286, 1735-1738.
-
(1999)
Science
, vol.286
, pp. 1735-1738
-
-
Bouillet, P.1
Metcalf, D.2
Huang, D.C.S.3
Tarlinton, D.M.4
Kay, T.W.H.5
Kontgen, F.6
Adams, J.M.7
Strasser, A.8
-
3
-
-
0028832667
-
A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions
-
Chittenden T., Flemingtgon C., Houghton A. B., Ebb R. G., Gall G. J., Elangovan B., Chinnadurai G. and Lutz R. J. (1995) A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions. EBMO J. 14, 5589-5596.
-
(1995)
EBMO J.
, vol.14
, pp. 5589-5596
-
-
Chittenden, T.1
Flemingtgon, C.2
Houghton, A.B.3
Ebb, R.G.4
Gall, G.J.5
Elangovan, B.6
Chinnadurai, G.7
Lutz, R.J.8
-
4
-
-
0032524885
-
The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9
-
Conradt B. and Horvitz H. R. (1998) The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9. Cell 93, 519-529.
-
(1998)
Cell
, vol.93
, pp. 519-529
-
-
Conradt, B.1
Horvitz, H.R.2
-
5
-
-
0027946686
-
Altered gene expression in neurons during programmed cell death: Identification of c-jun as necessary for neuronal apoptosis
-
Estus S., Zaks W. J., Freeman R. S., Gruda M., Bravo R. and Johnson E. M. Jr (1994) Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis. J. Cell Biol. 127, 1717-1727.
-
(1994)
J. Cell Biol.
, vol.127
, pp. 1717-1727
-
-
Estus, S.1
Zaks, W.J.2
Freeman, R.S.3
Gruda, M.4
Bravo, R.5
Johnson Jr., E.M.6
-
6
-
-
0034124301
-
Lovastatin potentiates antitumor activity and attenuates cardiotoxicity of doxorubicin in three tumor models in mice
-
Feleszko W., Mlynarczuk I., Balkowiec-Iskra E. Z., Czajka A., Switaj T., Stoklosa T., Giermasz A. and Jakóbisiak M. (2000) Lovastatin potentiates antitumor activity and attenuates cardiotoxicity of doxorubicin in three tumor models in mice. Clin. Cancer Res. 6, 2044-2052.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 2044-2052
-
-
Feleszko, W.1
Mlynarczuk, I.2
Balkowiec-Iskra, E.Z.3
Czajka, A.4
Switaj, T.5
Stoklosa, T.6
Giermasz, A.7
Jakóbisiak, M.8
-
7
-
-
0032559362
-
Rho GTPases and the actin cytoskeleton
-
Hall A. (1998) Rho GTPases and the actin cytoskeleton. Science 279, 509-514.
-
(1998)
Science
, vol.279
, pp. 509-514
-
-
Hall, A.1
-
8
-
-
0029012476
-
A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death
-
Ham J., Babij C., Whitfield J., Pfarr C. M., Lallemand D., Yaniv V. and Rubin L. L. (1995) A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death. Neuron 14, 927-939.
-
(1995)
Neuron
, vol.14
, pp. 927-939
-
-
Ham, J.1
Babij, C.2
Whitfield, J.3
Pfarr, C.M.4
Lallemand, D.5
Yaniv, V.6
Rubin, L.L.7
-
9
-
-
0035851204
-
BH3-only Bcl-2 family members are coordinately regulated by the JNK pathway and require Bax to induce apoptosis in neurons
-
Harris C. A. and Johnson E. M. Jr (2001) BH3-only Bcl-2 family members are coordinately regulated by the JNK pathway and require Bax to induce apoptosis in neurons. J. Biol. Chem. 276, 37754-37760.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 37754-37760
-
-
Harris, C.A.1
Johnson Jr., E.M.2
-
10
-
-
0035552572
-
Synergistic interaction of lovastatin and paclitaxel in human cancer cells
-
Holstein S. A. and Hohl R. J. (2001a) Synergistic interaction of lovastatin and paclitaxel in human cancer cells. Mol. Cancer Ther. 1, 141-149.
-
(2001)
Mol. Cancer Ther.
, vol.1
, pp. 141-149
-
-
Holstein, S.A.1
Hohl, R.J.2
-
11
-
-
0035020378
-
Interaction of cytosine arabinoside and lovastatin in human leukemia cells
-
Holstein S. A. and Hohl R. J. (2001b) Interaction of cytosine arabinoside and lovastatin in human leukemia cells. Leuk. Res. 25, 651-660.
-
(2001)
Leuk. Res.
, vol.25
, pp. 651-660
-
-
Holstein, S.A.1
Hohl, R.J.2
-
12
-
-
0032161337
-
BOD (Bcl-2-related ovarian death gene) is an ovarian BH3 domain-containing proapoptotic Bcl-2 protein capable of dimerization with diverse antiapoptotic Bcl-2 members
-
Hsu S. Y., Lin P. and Hsueh A. J. (1998) BOD (Bcl-2-related ovarian death gene) is an ovarian BH3 domain-containing proapoptotic Bcl-2 protein capable of dimerization with diverse antiapoptotic Bcl-2 members. Mol. Endo. 12, 1432-1440.
-
(1998)
Mol. Endo.
, vol.12
, pp. 1432-1440
-
-
Hsu, S.Y.1
Lin, P.2
Hsueh, A.J.3
-
13
-
-
0037265850
-
Down-regulation of Bcl-2 and Bcl-xL expression with bispecific antisense treatment of glioblastoma cell lines induce cell death
-
Jiang Z., Zheng X. and Rich K. M. (2003) Down-regulation of Bcl-2 and Bcl-xL expression with bispecific antisense treatment of glioblastoma cell lines induce cell death. J. Neurochem. 84, 273-281.
-
(2003)
J. Neurochem.
, vol.84
, pp. 273-281
-
-
Jiang, Z.1
Zheng, X.2
Rich, K.M.3
-
14
-
-
0028596288
-
Lovastatin induces growth inhibition and apoptosis in human malignant glioma cells
-
Jones K. D., Couldwell W. T., Hinton D. R., Su Y., He S., Anker L. and Law R. E. (1994) Lovastatin induces growth inhibition and apoptosis in human malignant glioma cells. Biochem. Biophys. Res. Commun. 205, 1681-1687.
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.205
, pp. 1681-1687
-
-
Jones, K.D.1
Couldwell, W.T.2
Hinton, D.R.3
Su, Y.4
He, S.5
Anker, L.6
Law, R.E.7
-
15
-
-
0032860424
-
Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells
-
Kaibuchi K., Kuroda S. and Amano M. (1999) Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells. Annu. Rev. Biochem. 68, 459-486.
-
(1999)
Annu. Rev. Biochem.
, vol.68
, pp. 459-486
-
-
Kaibuchi, K.1
Kuroda, S.2
Amano, M.3
-
16
-
-
0032933952
-
Lovastatin-induced apoptosis of human medulloblastoma cell lines in vitro
-
Macaulay R. J., Wang W., Dimitroulakos J., Becker L. E. and Yeger H. (1999) Lovastatin-induced apoptosis of human medulloblastoma cell lines in vitro. J. Neuro-Oncol. 42, 1-11.
-
(1999)
J. Neuro-Oncol.
, vol.42
, pp. 1-11
-
-
Macaulay, R.J.1
Wang, W.2
Dimitroulakos, J.3
Becker, L.E.4
Yeger, H.5
-
17
-
-
0032518787
-
Bim: A novel member of the Bcl-2 family that promotes apoptosis
-
O'Connor L., Strasser A., O'Reilly L. A., Hausmann G., Adams J. M., Cory S. and Huang D. C. S. (1998) Bim: a novel member of the Bcl-2 family that promotes apoptosis. EBMO J. 17, 384-395.
-
(1998)
EBMO J.
, vol.17
, pp. 384-395
-
-
O'Connor, L.1
Strasser, A.2
O'Reilly, L.A.3
Hausmann, G.4
Adams, J.M.5
Cory, S.6
Huang, D.C.S.7
-
19
-
-
0028307941
-
Inhibition of isoprenoid biosynthesis induces apoptosis in human promyelocytic HL-60 cells
-
Perez-Sala D. and Mollinedo F. (1994) Inhibition of isoprenoid biosynthesis induces apoptosis in human promyelocytic HL-60 cells. Biochem. Biophys. Res. Commun. 199, 1209-1215.
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.199
, pp. 1209-1215
-
-
Perez-Sala, D.1
Mollinedo, F.2
-
20
-
-
0036097786
-
Keeping killers on a tight leash: Transcriptional and post-translation control of the pro-apoptotic activity of BH3-only proteins
-
Puthalakath H. and Strasser A. (2002) Keeping killers on a tight leash: transcriptional and post-translation control of the pro-apoptotic activity of BH3-only proteins. Cell Death Differen. 9, 505-512.
-
(2002)
Cell Death Differen.
, vol.9
, pp. 505-512
-
-
Puthalakath, H.1
Strasser, A.2
-
21
-
-
0028958030
-
Bcl-2: Prevention of apoptosis as a mechanism of drug resistance
-
Reed J. C. (1995) Bcl-2: prevention of apoptosis as a mechanism of drug resistance. Hematol. Oncol. Clin. N. Am. 9, 451-473.
-
(1995)
Hematol. Oncol. Clin. N. Am.
, vol.9
, pp. 451-473
-
-
Reed, J.C.1
-
22
-
-
0032935664
-
Mitogen-activated protein kinases: Specific messages from ubiquitous messengers
-
Schaeffer H. J. and Weber M. J. (1999) Mitogen-activated protein kinases: specific messages from ubiquitous messengers. Mol. Cell. Biol. 19, 2435-2444.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 2435-2444
-
-
Schaeffer, H.J.1
Weber, M.J.2
-
23
-
-
0035135349
-
Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors
-
Shinjyo T., Kuribara R., Inukai T., Hosol H., Kinoshita T., Miyajima A., Houghton P. J., Look A. T., Oaawa K. and Inaba T. (2001) Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors. Mol. Cell Biol. 21, 854-864.
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 854-864
-
-
Shinjyo, T.1
Kuribara, R.2
Inukai, T.3
Hosol, H.4
Kinoshita, T.5
Miyajima, A.6
Houghton, P.J.7
Look, A.T.8
Oaawa, K.9
Inaba, T.10
-
24
-
-
0028947890
-
In vivo enhanced antitumor activity of carmustine [N,N'-bis (2-chloroethyl)-N-nitrosourea] by simvastatin
-
Soma M. R., Baetta R., De Renzis M. R., Mazzini G., Davegna C., Magrassi L., Butti G., Pezzotta S., Paoletti R. and Fumagalli R. (1995) In vivo enhanced antitumor activity of carmustine [N,N'-bis (2-chloroethyl)-N-nitrosourea] by simvastatin. Cancer Res. 55, 597-602.
-
(1995)
Cancer Res.
, vol.55
, pp. 597-602
-
-
Soma, M.R.1
Baetta, R.2
De Renzis, M.R.3
Mazzini, G.4
Davegna, C.5
Magrassi, L.6
Butti, G.7
Pezzotta, S.8
Paoletti, R.9
Fumagalli, R.10
-
25
-
-
0037094096
-
kip1 and Bim in response to IL-2
-
kip1 and Bim in response to IL-2. J. Immunol. 168, 5024-5031.
-
(2002)
J. Immunol.
, vol.168
, pp. 5024-5031
-
-
Stahl, M.1
Dijkers, P.F.2
Kops, G.J.P.L.3
Lens, S.M.A.4
Coffer, P.J.5
Burgering, B.M.T.6
Medema, R.H.7
-
26
-
-
0021821903
-
Involvement of the Bcl-2 gene in human follicular lymphoma
-
Tsujimoto Y., Cossman J., Jaffe E. and Croce C. (1985) Involvement of the Bcl-2 gene in human follicular lymphoma. Science 228, 1440-1443.
-
(1985)
Science
, vol.228
, pp. 1440-1443
-
-
Tsujimoto, Y.1
Cossman, J.2
Jaffe, E.3
Croce, C.4
-
27
-
-
0030968580
-
Rho GTPases and signaling networks
-
Van Aelst L. and D'Souza-Schorey C. (1997) Rho GTPases and signaling networks. Genes Dev. 11, 2295-2322.
-
(1997)
Genes Dev.
, vol.11
, pp. 2295-2322
-
-
Van Aelst, L.1
D'Souza-Schorey, C.2
-
28
-
-
0037592259
-
Microarray analysis uncovers the induction of the proapoptotic BH3-only protein Bim in multiple models of glucocortoid induced apoptosis
-
Wang Z., Malone M. H., He H., McColl K. S. and Distelhorst C. W. (2003) Microarray analysis uncovers the induction of the proapoptotic BH3-only protein Bim in multiple models of glucocortoid induced apoptosis. J. Biol. Chem. 278, 23861-23867.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 23861-23867
-
-
Wang, Z.1
Malone, M.H.2
He, H.3
McColl, K.S.4
Distelhorst, C.W.5
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