Polymorphism insertion/deletion of apolipoprotein B gene: Effect on lipid levels in obese patients;Polymorphisme insertion/délétion du gène de l'apolipoprotéine B: Effet sur les concentrations lipidiques chez les sujets obèses

Annales de Biologie Clinique

Volumn 62, Issue 2, 2004, Pages 183-188

  Jemaa, R ^a   Mebazaa, A ^a   Fumeron, F ^b  

^a LA RABTA HOSPITAL   (Tunisia)

^b UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Apolipoprotein B; Insertion deletion; Obesity; Polymorphism

Indexed keywords

APOLIPOPROTEIN; APOLIPOPROTEIN B; CHOLESTEROL;

ADULT; ARTICLE; BLOOD; FEMALE; GENE DELETION; GENE EXPRESSION REGULATION; GENETIC POLYMORPHISM; GENETICS; HUMAN; MALE; OBESITY;

ADULT; APOLIPOPROTEINS; APOLIPOPROTEINS B; CHOLESTEROL; FEMALE; GENE DELETION; HUMANS; MALE; MUTAGENESIS, INSERTIONAL; OBESITY; POLYMORPHISM, GENETIC;

INSERTION SEQUENCES;

EID: 1842457027     PISSN: 00033898     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Kannel WB, Castelli WP, Gordon T, Mc Namara PM. Serum cholesterol lipoproteins and risk of coronary heart disease : The Framingham heart study. Ann Internal Med 1971 ; 74 : 1-12.
2. Hong SH, Lee CC, Kim JQ. Genetic variation of the apolipoprotein B gene in Korean patients with coronary artery disease. Mol Cells 1997 ; 7 : 521-5.
3. Alavantic D, Glisic S, Kandic I. APOB3′ HVR polymorphism in healthy population relationships to serum lipid levels. Genet Epidemiol 1998 ; 15 : 113-22.
4. Guzman EC, Hirata MH, Quintao EC, Hirata RD. Association of the apolipoprotein B gene polymorphism with cholesterol levels and response to fluvastatin in Brazilian individuals with high risk for coronary heart disease. Clin Chem Lab Med 2000 ; 38 : 731-6.
5. Rajput-Williams J, Knott TJ, Wallis SC, et al. Variation of apolipoprotein B gene is associated with obesity, high blood cholesterol levels, and increased risk of coronary heart disease. Lancet 1988 ; ii : 1442-6.
6. Saha N, Tay JS, Heng CK, Humphries SE. DNA polymorphisms of the apolipoprotein B gene are associated with obesity and serum lipids in healthy Indians in Singapore. Clin Genet 1993 ; 43 : 113-20.
7. Ye P, Chen B, Wang S. Association of polymorphism of the apolipoprotein B gene with coronary heart disease in Han Chinese. Atherosclerosis 1995 ; 117 : 43-50.
8. Gardemann A, Ohly D, Fink M, et al. Association of the insertion/ deletion gene polymorphism of the apolipoprotein B signal peptide with myocardial infarction. Atherosclerosis 1988 ; 141 : 167-75.
9. Salazar LA, Hirata MH, Giannini SD, et al. Seven DNA polymorphisms at the candidate gene of atherosclerosis in Brazilian women with angiographically documented coronary disease. Clin Chim Acta 2000 ; 300 : 139-49.
10. National institute of health consensus development panel on the health implications of obesity. Health implications of obesity. Ann Intern Med 1985 ; 103 : 1073-7.
11. Burstein M, Scholnick HR, Morfin R. Rapid method for the isolation of lipoproteins from human serum by precipitation with polyanions. J Lipid Res 1970 ; 11 : 583-95.
12. Benlian P, Boileau C, Loux N, et al. Extended haplotypes and linkage disequilibrium between 11 markers at the APOAI-CIII-A4 gene cluster on chromosome 11. Am J Hum Genet 1991 ; 48 : 903-10.
13. Yang CY, Gu ZW, Weng SA, et al. Structure of apolipoprotein B-100 from human low density lipoprotein. Atherosclerosis 1989 ; 9 : 96-108.
14. Boerwinkle E, Chan L. A three codon insertion/deletion polymorphism in the signal peptide region of the human apolipoprotein B (apoB) gene directly typed by the polymerase chain reaction. Nucleic Acids Res 1989 ; 17 : 4003.
15. Hixon JE, Mc Mahan CA, McGill HC Jr, Strong JP. PDAY Research Group. Apo B insertion/deletion polymorphisms are associated with athe-rosclerosis in young black but not young white males. Artherioscler Thromb 1992 ; 12 : 1023-9.
16. Boerwinkle E, Chen SH, Visvikis S, et al. Signal peptide length variation in human apo B gene. Molecular characteristics and association with plasma glucose levels. Diabetes 1991 ; 40 : 1539-44.
17. Saha N, Tay JS, Chew CS. Influence of apolipoprotein B signal peptide insertion/deletion polymorphism on serum lipids and apolipoproteins in Chinese population. Clin Genet 1992 ; 41 : 152-6.
18. Xu CF, Tikkanen MJ, Huttunen JK, et al. Apolipoprotein B signal peptide insertion/deletion polymorphism is associated with Ag epitopes and involved in the determination of serum triglycerides levels. J lipid Res 1990 ; 31 : 1255-61.
19. Renges HH, Wile DB, Mc Keigne MR et al. Apolipoprotein B gene polymorphisms are associated with lipid levels in men of South Asian descent. Atherosclerosis 1991 ; 91 : 267-75.
20. Visvikis S, Cambou JP, Arvelier D, et al. Apolipoprotein B signal peptide polymorphism in patients with myocardial infarction and controls « The ECTIM study ». Hum Genet 1993 ; 90 : 561-5.
21. Bohn M, Bakken A, Eriksson J, Berg K. The apolipoprotein B signal peptide insertion deletion polymorphism is not associated with myocardial infarction in Norway. Clin Genet 1994 ; 45 : 255-9.
22. Visviskis S, Chan L, Siest G, et al. An insertion deletion polymorphism in the signal peptide of the human apolipoprotein B gene. Human Genet 1990 ; 84 : 373-5.
23. Gaffney D, Freeman DJ, Shepherd J, Packard CJ. The ins/del polymorphism in the signal peptide sequence of apolipoprotein B has no effect on lipid parameters. Clin Chim Acta 1993 ; 218 : 131-8.
24. Gajra B, Candlish JK, Saha N, et al. Influence of polymorphisms for apolipoprotein B (ins/del, XbaI, EcoRI) and apolipoprotein E on serum lipids and apolipoproteins in a Javanese population. Genet Epidemiol 1994 ; 11 : 19-27.
25. Wu JH, Wen MS, Lo SK, Chern MS. Increased frequency of apolipoprotein B signal peptide sp24/24 in patients with coronary artery disease. General allele survey in the population of Taiwan and comparison with Caucasians. Clin Genet 1994 ; 45 : 250-4.
26. Peacock R, Dunning A, Hamsten A, et al. Apolipoprotein B gene polymorphisms, lipoproteins and coronary atherosclerosis : a study of young myocardial infarction survivors and healthy population-based individuals. Atherosclerosis 1992 ; 92 : 151-64.
27. Saha N, Tay JS, Chew CS. Influence of apolipoprotein B signal peptide insertion/deletion polymorphism on serum lipids and apolipoproteins in a Chinese population. Clin Genet 1992 ; 41 : 152-6.
28. Randall LL, Hardy SJS. Unity in function in the absence of consensus in sequence role of leader pep tides in export. Science 1989 ; 243 : 1156-62.
29. Muller M. Proteolysis in protein import and export, signal peptide processing in eu-and prokaryotes. Experentia 1992 ; 48 : 118-29.
30. Turner PR, Talmud PJ, Visviskis S, et al. DNA polymorphisms of the apolipoprotein B gene are associated with altered plasma lipoprotein concentrations but not with perceived risk of cardiovascular disease. European atherosclerosis reasearch study. Atherosclerosis 1995 ; 116 : 221-34.
31. Jemaa R, El Asmi M, Mebazaa A, Fumeron F. Association entre polymorphisme XbaI du gène de l'apolipoprotéine B et variations des concentrations lipidiques chez les sujets obèses. Rev Tun Biol Clin 2001 ; 12 : 32-7.