Chiral separation and modeling of the three-chiral-center β-blocker drug nadolol by simulated moving bed chromatography

Journal of Chromatography A

Volumn 1035, Issue 2, 2004, Pages 167-176

  Wang, Xin ^a   Ching, Chi Bun ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Cyclodextrin; Enantiomer separation; Nadolol; Simulated moving beds

Indexed keywords

DISEASES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MIXTURES; SILICA GEL;

CHIRAL SEPARATION; HYPERTENSION;

DRUG PRODUCTS;

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; NADOLOL;

ANALYTIC METHOD; ARTICLE; CHIRALITY; CHROMATOGRAPHY; ENANTIOMER; MOLECULAR MODEL; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RACEMIC MIXTURE; SEPARATION TECHNIQUE; SIMULATION; STEADY STATE;

ADRENERGIC BETA-ANTAGONISTS; CHROMATOGRAPHY, LIQUID; NADOLOL; STEREOISOMERISM;

ANGINA;

EID: 1842428631     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2004.02.048     Document Type: Article

References (22)

1. Krstulovic A.M. J. Chromatogr. 488:1989;53.
2. S. Ahuja, in: H.Y. Aboul-Enein, I.W. Wainer (Eds.), The Impact of Stereochemistry in Drug Development and Use, John Wiley and Sons, New York, 1997, p. 287.
3. Anon. Chirality 4 (1992) 338.
4. Francotte E., Richert P., Mazzotti M., Morbidelli M. J. Chromatogr. A. 796:1998;239.
5. Pais S.L., Loureiro M.J., Rodrigues A.E. Chem. Eng. Sci. 52:1997;245.
6. Khattabi S., Cherrak D.E., Mihlbachler K., Guiochon G. J. Chromatogr. A. 877:2000;95.
7. Ching C.B., Lim B.G., Lee E.J.D., Ng S.C. J. Chromatogr. 634:1993;215.
8. Mazzotti M., Storti G., Morbidelli M. AIChE J. 40:1994;1825.
9. Migliorini C., Mazzotti M., Morbidelli M. Sep. Purif. Technol. 20:2000;79.
10. Mata V., Rodrigues A.E. J. Chromatogr. A. 939:2001;23.
11. http://www.organo.co.jp/technology/hisepa/en_hisepa/newjo/jo1.html.
12. D.C.S. Azevedo, A.E. Rodrigues, Carbohydrate Separation From Cashew Apple Juice: Experimental Data in SMB, AIChE Meeting in Indianapolis, 2002.
13. Wang X., Ching C.B. Sep. Sci. Technol. 37:2002;2567.
14. Storti G., Masi M., Carra S. Chem. Eng. Sci. 44:1989;1329.
15. Storti G., Mazzotti M., Morbidelli M., Carra S. AIChE J. 39:1993;471.
16. Storti G., Mazzotti M., Morbidelli M., Bachiocci R. Ind. Eng. Chem. Res. 34:1995;288.
17. Mazzotti M., Storti G., Morbidelli M. AIChE J. 42:1996;2784.
18. Mazzotti M., Storti G., Morbidelli M. AIChE J. 43:1997;64.
19. Mazzotti M., Storti G., Morbidelli M. J. Chromatogr. A. 769:1997;3.
20. Ruthven D.M., Ching C.B. Chem. Eng. Sci. 44:1989;1011.
21. Migliorini C., Mazzotti M., Morbidelli M. AIChE J. 45:1999;1411.
22. Wang X., Ching C.B. Ind. Eng. Chem. Res. 42:2003;6171.