Metabolic engineering: Prospects for crop improvement through the genetic manipulation of phenylpropanoid biosynthesis and defense responses - A review

Gene

Volumn 179, Issue 1, 1996, Pages 61-71

  Dixon, Richard A ^a   Lamb, Chris J ^b   Masoud, Sameer ^a   Sewalt, Vincent J H ^a   Paiva, Nancy L ^a  

^a PLANT BIOLOGY DIVISION   (United States)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

Forage digestibility; Glucanase; Lignin modification; Medicago sativa; Metabolic compartmentation; Nodulation; Phytoalexin response

Indexed keywords

CHALCONE; FLAVONOID; GLUCAN GLUCOSIDASE; ISOFLAVONE; ISOFLAVONOID; LIGNIN; PHENYLPROPANOID; PLANT DNA; PROPIONIC ACID DERIVATIVE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; VEGETABLE PROTEIN;

ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; CROP; DISEASE RESISTANCE; GENE EXPRESSION REGULATION; GENETIC ENGINEERING; GENETIC MANIPULATION; HIGHER PLANT; LEGUME; MICROORGANISM; MOLECULAR BIOLOGY; MYCOSIS; NONHUMAN; OOMYCETES; PHYTOCHEMISTRY; PLANT GROWTH; PRIORITY JOURNAL; RHIZOBIUM; SYMBIOSIS; TRANSGENIC PLANT; VASCULAR TISSUE;

AGRICULTURE; BENZENE DERIVATIVES; BIOTECHNOLOGY; GENETIC ENGINEERING; MEDICAGO SATIVA;

EMBRYOPHYTA; FABACEAE; MEDICAGO SATIVA; OOMYCETES; PHYTOPHTHORA; RHIZOBIUM;

EID: 1842411478     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(96)00327-7     Document Type: Article

References (76)

1. Albrecht, K.A., Wedin, W.F. and Buxton, D.R. (1987) Cell-wall composition and digestibility of alfalfa stems and leaves. Crop Sci. 27, 735-741.
2. Atanassova, R., Favet, N., Martz, F., Chabbert, B., Tollier, M.-T., Monties, B., Fritig, B. and Legrand, M. (1995) Altered lignin composition in transgenic tobacco expressing O-methyltransferase sequences in sense and antisense orientation. Plant J. 8, 465-477.
3. Ballance, G.M. and Dixon, R.A. (1995) Medicago sativa cDNAs encoding chalcone reductase. Plant Physiol. 107, 1027-1028.
4. Bate, N.J., Orr, J., Ni, W., Meroni, A., Nadler-Hassar, T., Doerner, P.W., Dixon, R.A., Lamb, C.J. and Elkind, Y. (1994) Quantitative relationship between phenylalanine ammonia-lyase levels and phenylpropanoid accumulation in transgenic tobacco identifies a rate determining step in natural product synthesis. Proc. Natl. Acad. Sci. USA 91, 7608-7612.
5. Benhamou, N., Broglie, K., Chet, I. and Broglie R. (1993) Cytology of infection of 35S-bean chitinase transgenic canola plants by Rhizoctonia solani: cytochemical aspects of chitin breakdown in vivo. Plant J. 4, 295-305.
6. Biggs, D.R., Welle, R., Visser, F.R. and Grisebach, H. (1987) Dimethylallylpyrophosphate: 3,9-dihydroxypterocarpan 10-dimethylallyl transferase from Phaseolus vulgaris. FEBS Lett. 220, 223-226.
7. Boller, T. (1993) Antimicrobial functions of the plant hydrolases, chitinase and β-1,3-glucanase. In: Fritig, B. and Legrand M. (Eds.), Mechanisms of Plant Defense Responses. Kluwer Academic Publishers, Dordrecht, pp. 391-400.
8. Boudet, A.M., Lapierre, C. and Grima-Pettenati, J. (1995) Biochemistry and molecular biology of lignification. New Phytol. 129, 203-236.
9. Broglie, R. and Broglie K. (1993) Chitinases and plant protection. In: Fritig, B. and Legrand, M. (Eds.), Mechanisms of Plant Defense Responses. Kluwer Academic Publishers, Dordrecht, pp. 411-421.
10. Broglie, K., Chet, I., Holliday, M., Cressman, R., Biddle, P., Knowlton, S., Mauvais, C.J. and Broglie, R. (1991) Transgenic plants with enhanced resistance to the fungal pathogen Rhizoctonia solani. Science 254, 1194-1197.
11. Buxton, D.R. and Russell, J.R. (1988) Lignin constituents and cell-wall digestibility of grass and legume stems. Crop Sci. 28, 553-558.
12. Casler, M.D. (1987) In vitro digestibility of dry matter and cell wall constituents of smooth bromegrass forage. Crop Sci. 27, 931-934.
13. Dakora, F.D. (1995) Plant flavonoids: biological molecules for useful exploitation. Aust. J. Plant Physiol. 22, 87-99.
14. Dangl, J.L. (1992) Regulatory elements controlling developmental and stress-induced expression of phenylpropanoid genes. In: Boller, T. and Meins, F. (Eds.), Plant Gene Research: Genes Involved in Plant Defense. Springer-Verlag, New York, NY, pp. 303-326.
15. Davin, L.B. and Lewis, N.G. (1992) Phenylpropanoid metabolism: biosynthesis of monolignols, lignans and neolignans, lignins and suberins. Rec. Adv. Phytochem. 26, 325-375.
16. Dewick, P.M. and Martin, M. (1979) Biosynthesis of pterocarpan, isoflavan and coumestan metabolites of Medicago sativa: chalcone, isoflavone and isoflavanone precursors. Phytochemistry 18, 597-602.
17. Dixon, R.A. and Paiva, N.L. (1993) Prospects for the genetic manipulation of antimicrobial plant secondary products. In: Beadle D.J., Bishop, D.H.L., Copping L.G., Dixon G.K. and Holloman D.W. (Eds.), Opportunities for Molecular Biology in Crop Production. British Crop Protection Council, Farnham, pp. 113-118.
18. Dixon, R.A. and Paiva, N.L.(1995) Stress-induced phenylpropanoid metabolism. Plant Cell 7, 1085-1097.
19. Dixon, R.A., Blyden, E.R., Robbins, M.P., Van Tunen, A.J. and Mol, J.N.M. (1988) Comparative biochemistry of chalcone isomerases. Phytochemistry 27, 2801-2808.
20. Dixon R.A., Maxwell, C.A., Ni, W., Oommen, A. and Paiva, N.L. (1994) Genetic manipulation of lignin and phenylpropanoid compounds involved in interactions with microorganisms. Rec. Adv. Phytochem. 28, 153-178.
21. Dixon, R.A., Battacharyya, M.K. and Paiva, N.L. (1995a) Engineering disease resistance in plants: an overview. In: Singh ,R.P. and Singh, U.S. (Eds.), Advanced Methods in Plant Pathology. CRC Press, Boca Raton, FL, pp. 249-270.
22. Dixon, R.A., Harrison, M.J. and Paiva, N.L. (1995b) The isoflavonoid phytoalexin pathway: from enzymes to genes to transcription factors. Physiol. Plant. 93, 385-392.
23. Dwivedi, U.N., Campbell, W.H., Yu, J., Datla, R.S.S., Bugos, R.C., Chiang, V.L. and Podila, G.K. (1994) Modification of lignin biosynthesis in transgenic Nicotiana through expression of an antisense O-methyltransferase gene from Populus. Plant Mol. Biol. 26, 1-71.
24. Edwards, R. and Dixon, R.A. (1991a) Isoflavone O-methyltransferase activities in elicitor-treated cell suspension cultures of Medicago sativa. Phytochemistry 30, 2597-2606.
25. Edwards, R. and Dixon, R.A. (1991b) Purification and characterization of S-adenosyl-L-methionine: caffeic acid 3-O-methyl-transferase from suspension cultures of alfalfa (Medicago sativa L.). Arch. Biochem. Biophys. 287, 372-379.
26. Elkind, Y., Edwards, R., Mavandad, M., Hedrick, S.A., Ribak, O., Dixon, R.A. and Lamb, C.J. (1990) Abnormal plant development and down regulation of phenylpropanoid biosynthesis in transgenic tobacco containing a heterologous phenylalanine ammonia-lyase gene. Proc. Natl. Acad. Sci. USA, 87, 9057-9061.
27. Esnault, R., Buffard, D., Breda, C., Sallaud, C., El Turk, J. and Kondorosi, A. (1993) Pathological and molecular characterization of alfalfa interactions with compatible and incompatible bacteria, Xanthomonas campestris pv. alfalfae and Pseudomonas syringae pv. pisi. Mol. Plant Microb. Interact. 6, 655-664.
28. Fields, S. and Song, O.-K. (1989) A novel genetic system to detect protein-protein interactions. Nature 340, 245-246.
29. Gowri, G., Bugos, R.C., Campbell, W.H., Maxwell, C.A. and Dixon, R.A. (1991) Stress responses in alfalfa (Medicago sativa L.), X. Molecular cloning and expression of S-adenosyl-L-methionine: caffeic acid 3-O-methyltransferase, a key enzyme of lignin biosynthesis. Plant Physiol. 97, 7-14.
30. Gunia, W., Hinderer, W., Wittkampf, U. and Barz, W. (1991) Elicitor induction of cytochrome P450 monooxygenases in cell suspension cultures of chickpea (Cicer arietinum L.) and their involvement in pterocarpan phytoalexin biosynthesis. Z. Naturforsch. 46c, 58-66.
31. Guo, L. and Paiva, N.L. (1995) Molecular cloning and expression of alfalfa (Medicago sativa L.) vestitone reductase, the penultimate enzyme in medicarpin biosynthesis. Arch. Biochem. Biophys., in press.
32. Guo, L., Dixon, R.A. and Paiva, N.L. (1994) Conversion of vestitone to medicarpin in alfalfa (Medicago sativa L.) is catalyzed by two independent enzymes. J. Biol. Chem. 269, 22372-22378.
33. Hain, R., Reif, H.-J., Krause, E., Langebartels, R., Kindl, H., Vornam, B., Wiese, W., Schmelzer, E., Schrier, P.H., Stöcker, R.H. and Stenzel, K. (1993) Disease resistance results from foreign phytoalexin expression in a novel plant. Nature 361, 153-156.
34. Halpin, C., Knight, M.E., Foxon, G.A., Campbell, M.M., Boudet, A.M., Boon, J.A., Chabbert, B., Tollier, M.-T. and Schuch, W. (1994) Manipulation of lignin quality by downregulation of cinnamyl alcohol dehydrogenase. Plant J. 6, 339-350.
35. Hrazdina, G. (1992) Compartmentation in aromatic metabolism. In: Stafford, H. and Ibrahim, R.K. (Eds.), Phenolic Metabolism in Plants. Plenum, New York, NY, pp. 1-23.
36. Hrazdina, G. and Wagner, G. (1985) Metabolic pathways as enzyme complexes: evidence for the synthesis of phenylpropanoids and flavonoids on membrane-associated enzyme complexes. Arch. Biochem. Biophys. 237, 88-100.
37. Jung, H.G. and Vogel, K.P. (1986) Influence of lignin on digestibility of forage cell wall material. J. Anim. Sci. 62, 1703-1712.
38. Jung, H.G., Smith, R.R. and Endres, C.S. (1994) Cell wall composition and degradability of stem tissue from lucerne divergently selected for lignin and in vitro dry-matter disappearance. Grass Forage Sci. 49, 295-304.
39. Junghans, H., Dalkin, K. and Dixon, R.A (1993) Stress responses in alfalfa (Medicago sativa L.). 15. Characterization and expression of members of a subset of the chalcone synthase multigene family. Plant Mol. Biol. 22, 239-253.
40. Keen, N.T. and Yoshikawa, M. (1983) β-1,3-Endoglucanase from soybean releases elicitor-active carbohydrates from fungus cell walls. Plant Physiol. 71, 460-465.
41. Kessmann, H., Choudhary, A.D. and Dixon, R.A. (1990) Stress responses in alfalfa (Medicago sativa L.), III. Induction of medicarpin and cytochrome P450 enzyme activities in elicitor-treated cell suspension cultures and protoplasts. Plant Cell Rep. 9, 38-41.
42. Kochs, G. and Grisebach, H. (1986) Enzymic synthesis of isoflavones. Eur. J. Biochem. 155, 311-318.
43. Lamb, C.J., Ryals, J.A., Ward, E.R. and Dixon, R.A. (1992) Emerging strategies for enhancing crop resistance to microbial pathogens. Bio/ Technology 10, 1436-1445.
44. Mackenbrock, U.M., Vogelsang, R. and Barz, W. (1992) Isoflavone and pterocarpan malonylglucosides and β-1,3-glucan-and chitin-hydrolases are vacuolar constituents in chickpea (Cicer arietinum L.) Z. Naturforsch. 47c, 815-822.
45. Maher, E.A., Lamb C.J. and Dixon, R.A. (1994) Stress response in alfalfa (Medicago sativa L), XVII. Identification of multiple hydrolases and molecular characterization of an acidic glucanase. Physiol. Mol. Plant Pathol. 43, 329-342.
46. Masoud, S.A., Zhu, Q., Lamb, C.J. and Dixon, R.A. (1996) Constitutive expression of an inducible β-1,3-glucanase in alfalfa reduces disease severity caused by the oomycete pathogen Phytophthora megasperma f. sp. medicaginis, but does not reduce disease severity of chitin-containing fungi. Transgenic Res. 5 (in press).
47. Mauch, F., Mauch-Mani, B. and Boller, T. (1988) Antifungal hydrolases in pea tissue, II. Inhibition of fungal growth by combinations of chitinase and β-1,3-glucanase. Plant Physiol. 88, 936-942.
48. Maxwell, C.A., Edwards, R. and Dixon, R.A. (1992) Identification, purification and characterization of S-adenosyl-L-methionine: isoliquiritigenin 2′-O-methyltransferase from alfalfa (Medicago sativa L.). Arch. Biochem. Biophys. 293, 158-166.
49. Maxwell, C.A., Hartig, U.A., Joseph, C.M. and Phillips, D.A. (1989) A chalcone and two related flavonoids released from alfalfa roots induce nod genes of Rhizobium meliloti. Plant Physiol. 91, 842-847.
50. Maxwell, C.A., Harrison, M.J. and Dixon, R.A. (1993) Molecular characterization and expression of alfalfa isoliquiritigenin 2′-O-methyltransferase, an enzyme specifically involved in the biosynthesis of and inducer of Rhizobium meliloti nodulation genes. Plant J. 4, 971-981.
51. McKhann, H.I. and Hirsch, A.M. (1994) Isolation of chalcone synthase and chalcone isomerase cDNAs from alfalfa (Medicago sativa L.): highest transcript levels occur in young roots and root tips. Plant Mol. Biol. 24, 767-777.
52. Ni, W., Paiva, N.L. and Dixon, R.A. (1994). Reduced lignin in transgenic plants containing an engineered caffeic acid O-methyltransferase antisense gene. Transgenic Res. 3, 120-126.
53. Oommen, A., Dixon, R.A. and Paiva, N.L. ( 1994) The elicitor-inducible alfalfa isoflavone reductase promoter confers different patterns of developmental expression in homologous and heterologous transgenic plants. Plant Cell 6, 1789-1803.
54. Paiva, N.L., Edwards, R., Sun, Y., Hrazdina, G. and Dixon, R.A. (1991) Stress responses in alfalfa (Medicago sativa E.), XI. Molecular cloning and expression of alfalfa isoflavone reductase, a key enzyme of isoflavonoid phytoalexin biosynthesis. Plant Mol. Biol. 17, 653-667.
55. Paiva, N.L., Oommen, A., Harrison, M.J. and Dixon, R.A. (1994) Regulation of isoflavonoid metabolism in alfalfa. Plant Cell Tissue Organ Cult. 38, 213-220.
56. Pakusch, A.E., Kneusel, R.E. and Matern, U. (1989) S-Adenosyl-L-methionine: trans-caffeoyl-coenzyme A 3-O-methyltransferase from elicitor-treated parsley cell suspension cultures. Arch. Biochem. Biophys. 271, 488-494.
57. Reeves III, J.B. (1985) Lignin composition of chemically treated feeds as determined by nitrobenzene oxidation and its relationship to digestibility. J. Dairy Sci. 68, 1976-1983.
58. Reeves III, J.B. (1987) Lignin and fiber compositional changes in forages over a growing season and their effects on in vitro digestibility. J. Dairy Sci. 70, 1583-1594.
59. Schlumbaum, A., Mauch, F., Vogeli, U. and Boller, T. (1986) Plant chitinases are potent inhibitors of fungal growth. Nature 324, 365-367.
60. Sewalt, V.J.H., Fontenot, J.P. and Allen, V.G. (1993) Changes in composition and digestibility of corn stover fractions during maturation. In: Faw, W. and Pederson, G.A. (Eds.), The Dollars and Sense of Forages. AFGC Proceedings, Vol. 2, pp. 211-215.
61. Sewalt, V.J.H., Glasser, W.G., Fontenot, J.P and Allen, V.G. (1996) Lignin impact on fiber degradation, 1. Quinone methide intermediates formed from lignin during in vitro fermentation of corn stover. J. Sci. Food Agric. 71, in press.
62. Srere, P.A. (1987) Complexes of sequential metabolic enzymes. Annu. Rev. Biochem. 56, 89-124.
63. Tabe, L.M., Higgins, C.M., NcNabb, W.C. and Higgins, T.J.V. (1993) Genetic engineering of grain and pasture legumes for improved nutritive value. Genetica 90, 181-200.
64. Tien, M. (1987) Properties of ligninases from Phanerochaete chrysosporium and their possible applications. CRC Crit. Rev. Microbiol. 15, 141-168.
65. Van Doorsselaere, J., Baucher, M., Chognot, E., Chabbert, B., Tollier, M.-T., Petit-Conil, M., Leplé, J.-C., Pilate, G., Cornu, D., Monties, B., Van Montagu, M., Inzé, D., Boerjan, W. and Jouanin, E. (1995) A novel lignin in poplar trees with a reduced caffeic acid/ 5-hydroxyferulic acid O-methyltransferase activity. Plant J. 8, 855-864.
66. VanEtten, H.D., Matthews, D.E. and Matthews, P.S. (1989) Phytoalexin detoxification: importance for pathogenicity and practical implications. Annu. Rev. Phytopathol. 27, 143-164.
67. Vögeli-Lange, R., Fründt, C., Hart, C.M., Nagy, F. and Meins Jr. F. (1994) Developmental, hormonal and pathogenesis-related regulation of the tobacco class I β-1,3-glucanase B promoter. Plant Mol. Biol. 25, 299-311.
68. Welle, R., Schröder, G., Schiltz, E., Grisebach, H. and Schröder, J. (1991) Induced plant responses to pathogen attack: analysis and heterologous expression of the key enzyme in the biosynthesis of phytoalexins in soybean (Glycine max L). Eur. J. Biochem. 196, 423-430.
69. Whetten, R. and Sederoff, R. (1991) Genetic engineering of wood. Forest Ecol. Manage. 43, 301-316.
70. Ye, Z.-H. and Varner, J.E. (1995) Differential expression of two O-methyltransferases in lignin biosynthesis in Zinnia elegans. Plant Physiol. 108, 459-467.
71. Ye, Z.-H., Kneusel, R.E., Matern, U. and Varner, J.E. (1994) An alternative methylation pathway in lignin biosynthesis in Zinnia. Plant Cell 6, 1427-1439.
72. Yoshikawa, M., Tsuda, M. and Takeuchi, Y. (1993) Resistance to fungal diseases in transgenic tobacco plants expressing the phytoalexin elicitor-releasing factor, β-1,3-endoglucanase, from soybean. Naturwissenschaften 80, 17-420.
73. Yu, L.M., Lamb, C.J. and Dixon, R.A. (1993) Purification and biochemical characterization of two proteins which bind to the H-box cis-element implicated in transcriptional activation of plant defense genes. Plant J. 3, 805-816.
74. Zhu, Q. and Lamb, C.J. (1991) Isolation and characterization of a rice gene encoding a basic chitinase. Mol. Gen. Genet. 226, 289-296.
75. Zhu, Q., Doerner, P.W. and Lamb, C.J. (1993) Stress induction and developmental regulation of a rice chitinase promoter in transgenic tobacco. Plant J. 3, 203-212.
76. Zhu, Q., Maher, E.A., Masoud, S., Dixon R.A. and Lamb C.J. (1994) Enhanced protection against fungal attack by constitutive co-expression of chitinase and glucanase genes in transgenic tobacco. Bio/Technology 12, 807-812.