Tumor necrosis factor blockade in actively induced experimental autoimmune encephalomyelitis prevents clinical disease despite activated T cell infiltration to the central nervous system

European Journal of Immunology

Volumn 27, Issue 8, 1997, Pages 1973-1981

  Körner, Heinrich ^a   Lemckert, Frances A ^a   Chaudhri, Geeta ^b   Etteldorf, Susanne ^a,c   Sedgwick, Jonathon D ^a  

^a ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c BASEL INSTITUTE FOR IMMUNOLOGY   (Switzerland)

Author keywords

Autoimmunity; Central nervous system; Experimental autoimmune encephalomyelitis; Tumor necrosis factor; Tumor necrosis factor receptor

Indexed keywords

BETA1 INTEGRIN; CD4 ANTIGEN; FREUND ADJUVANT; HYBRID PROTEIN; IMMUNOGLOBULIN G; INTERLEUKIN 2 RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MYELIN BASIC PROTEIN; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DEMYELINATION; DISEASE SEVERITY; FEMALE; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; INTRAPERITONEAL DRUG ADMINISTRATION; LYMPHOCYTIC INFILTRATION; NONHUMAN; PARALYSIS; PRIORITY JOURNAL; RAT; T LYMPHOCYTE ACTIVATION; WEIGHT REDUCTION;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CENTRAL NERVOUS SYSTEM; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; IMMUNOGLOBULIN G; LYMPHOCYTE ACTIVATION; MICROGLIA; MYELIN BASIC PROTEINS; NEUTRALIZATION TESTS; RATS; RATS, INBRED LEW; RECEPTORS, TUMOR NECROSIS FACTOR; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 1842407250     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.1830270822     Document Type: Article

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