메뉴 건너뛰기




Volumn 38, Issue 3, 1997, Pages 250-266

Thymic nurse cells: Their functional ultrastructure

Author keywords

Epithelial nurse cell; Lympho epithelial complexes; Scanning electron microscopy; Transmission electron microscopy

Indexed keywords

CYTOLOGY; HIGH RESOLUTION TRANSMISSION ELECTRON MICROSCOPY; NURSING; SCANNING ELECTRON MICROSCOPY; THYMUS;

EID: 1842373334     PISSN: 1059910X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0029(19970801)38:3<250::AID-JEMT6>3.0.CO;2-Q     Document Type: Article
Times cited : (22)

References (56)
  • 1
    • 0021918626 scopus 로고
    • The murine thymic nurse cell: An izolated thymic microenvironment
    • Andrews, P., and Boyd, R.L. (1985) The murine thymic nurse cell: An izolated thymic microenvironment. Eur. J. Immunol., 15:36-42.
    • (1985) Eur. J. Immunol. , vol.15 , pp. 36-42
    • Andrews, P.1    Boyd, R.L.2
  • 2
    • 0024357880 scopus 로고
    • Thymic nurse cells: Division of thymocytes within complexes
    • Brelinska, R. (1989) Thymic nurse cells: Division of thymocytes within complexes. Cell Tissue Res., 258:637-643.
    • (1989) Cell Tissue Res. , vol.258 , pp. 637-643
    • Brelinska, R.1
  • 3
    • 85165103676 scopus 로고
    • Epithelial-lymphoid cell complexes in the thymus during methylnitrosourea-induced leukemogenesis
    • Brelinska, R. (1991) Epithelial-lymphoid cell complexes in the thymus during methylnitrosourea-induced leukemogenesis. Verh. Anat. Ges., 84:323-324.
    • (1991) Verh. Anat. Ges. , vol.84 , pp. 323-324
    • Brelinska, R.1
  • 4
    • 0021846380 scopus 로고
    • Distribution of different cell types within the rat thymus in neonatal period of life
    • Brelinska, R., Kaczmarek, E., Warchol, J.B., and Jaroszewski, J. (1985) Distribution of different cell types within the rat thymus in neonatal period of life. Cell Tissue Res., 240:473-478.
    • (1985) Cell Tissue Res. , vol.240 , pp. 473-478
    • Brelinska, R.1    Kaczmarek, E.2    Warchol, J.B.3    Jaroszewski, J.4
  • 5
    • 0022531410 scopus 로고
    • Multicellular complexes of thymocytes and different types of thymic stromal cells in the mouse
    • Brelinska, R., Houben-Defresne, M.P., and Boniver, J. (1986) Multicellular complexes of thymocytes and different types of thymic stromal cells in the mouse. Cell Tissue Res., 244:673-679.
    • (1986) Cell Tissue Res. , vol.244 , pp. 673-679
    • Brelinska, R.1    Houben-Defresne, M.P.2    Boniver, J.3
  • 6
    • 0023905478 scopus 로고
    • Murine thymic multicellular complexes during latency period after methylnitrosourea (MNU) injection
    • Brelinska, R., Seidel, H.J., Warchol, J.B., and Kreja, L. (1988) Murine thymic multicellular complexes during latency period after methylnitrosourea (MNU) injection. Thymus, 11:67-75.
    • (1988) Thymus , vol.11 , pp. 67-75
    • Brelinska, R.1    Seidel, H.J.2    Warchol, J.B.3    Kreja, L.4
  • 7
    • 0025973817 scopus 로고
    • Thymic nurse cells: Differentiation of thymocytes within complexes
    • Brelinska, R., Seidel, H.J., and Kreja, L. (1991) Thymic nurse cells: Differentiation of thymocytes within complexes. Cell Tissue Res., 264:175-183.
    • (1991) Cell Tissue Res. , vol.264 , pp. 175-183
    • Brelinska, R.1    Seidel, H.J.2    Kreja, L.3
  • 8
    • 0024851877 scopus 로고
    • Immunohistochemical localization of six cytokeratin-defined subsets of the rat thymic epithelial cells
    • Colic, M., Jovanovic, S., Mitrowic, S., and Dujic, A. (1989) Immunohistochemical localization of six cytokeratin-defined subsets of the rat thymic epithelial cells. Thymus, 13:175-185.
    • (1989) Thymus , vol.13 , pp. 175-185
    • Colic, M.1    Jovanovic, S.2    Mitrowic, S.3    Dujic, A.4
  • 9
    • 0022588433 scopus 로고
    • In situ characterization in freeze-fractured mouse thymuses of lymphoepithelial complexes ultrastructurally similar to isolated thymic nurse cells
    • Defresne, M.P., Goffinet, G., and Boniver, J. (1986a) In situ characterization in freeze-fractured mouse thymuses of lymphoepithelial complexes ultrastructurally similar to isolated thymic nurse cells. Tissue Cell 18:321-330.
    • (1986) Tissue Cell , vol.18 , pp. 321-330
    • Defresne, M.P.1    Goffinet, G.2    Boniver, J.3
  • 10
    • 0022517663 scopus 로고
    • Cellular aspects of radiation leukemogenesis. II. Thymic microenvironment and nurse cells
    • Defresne, M.P., Rongy, A.M., and Boniver, J. (1986b) Cellular aspects of radiation leukemogenesis. II. Thymic microenvironment and nurse cells. Leukemia Res., 10:783-789.
    • (1986) Leukemia Res. , vol.10 , pp. 783-789
    • Defresne, M.P.1    Rongy, A.M.2    Boniver, J.3
  • 11
    • 0024788983 scopus 로고
    • Control of lymphoepithelial interactions within thymic nurse cells by gamma-interferon and tumor necrosis factor alpha. Possible role in the modulation of intrathymic education?
    • Defresne, M.P., Humblet, C., Rongy, A.M., and Boniver, J. (1989) Control of lymphoepithelial interactions within thymic nurse cells by gamma-interferon and tumor necrosis factor alpha. Possible role in the modulation of intrathymic education? Thymus, 13:201-204.
    • (1989) Thymus , vol.13 , pp. 201-204
    • Defresne, M.P.1    Humblet, C.2    Rongy, A.M.3    Boniver, J.4
  • 12
    • 0025128824 scopus 로고
    • Effect of interferon-gamma and tumor necrosis factor-alpha on lymphoepithelial interactions within thymic nurse cells
    • Defresne, M.P., Humblet, C., Rongy, A.M., Greimers, R., and Boniver, J. (1990) Effect of interferon-gamma and tumor necrosis factor-alpha on lymphoepithelial interactions within thymic nurse cells. Eur. J. Immunol., 20:429-432.
    • (1990) Eur. J. Immunol. , vol.20 , pp. 429-432
    • Defresne, M.P.1    Humblet, C.2    Rongy, A.M.3    Greimers, R.4    Boniver, J.5
  • 13
    • 0028177151 scopus 로고
    • The ER-TR4 monoclonal antibody recognizes murine thymic epithelial cells (type I) and inhibits their capacity to interact with murine thymocytes: Immunoelectron microscopic and functional studies
    • Defresne, M.P., Nabarra, B., Vliet, E. van, Willemsen, R. van, Dongen, H., and Ewijk, W. van (1994) The ER-TR4 monoclonal antibody recognizes murine thymic epithelial cells (type I) and inhibits their capacity to interact with murine thymocytes: Immunoelectron microscopic and functional studies. Histochemistry, 101:335-363.
    • (1994) Histochemistry , vol.101 , pp. 335-363
    • Defresne, M.P.1    Nabarra, B.2    Van Vliet, E.3    Van Willemsen, R.4    Dongen, H.5    Van Ewijk, W.6
  • 15
    • 0025936922 scopus 로고
    • Immunohistochemical characterization of nurse cells in normal human thymus
    • Dispasquale, B., and Tridente, G. (1991) Immunohistochemical characterization of nurse cells in normal human thymus. Histochemistry, 96:499-503.
    • (1991) Histochemistry , vol.96 , pp. 499-503
    • Dispasquale, B.1    Tridente, G.2
  • 17
    • 0025865852 scopus 로고
    • Thymic nurse cells (TNC) in spontaneous thymoma BUF/Mna rats as a model to study their roles in T-cell development
    • Ezaki, T., Matsuno, K., and Kotani, M. (1991) Thymic nurse cells (TNC) in spontaneous thymoma BUF/Mna rats as a model to study their roles in T-cell development. Immunology, 73:151-158.
    • (1991) Immunology , vol.73 , pp. 151-158
    • Ezaki, T.1    Matsuno, K.2    Kotani, M.3
  • 18
    • 0027255643 scopus 로고
    • Phenotypically diverse mouse thymic stromal cell lines which induce proliferation and differentiation of hematopoietic cells
    • Faas, S.J., Rothstein, J.L., Kreider, B.L., Rovera, G., and Knowles, B.B. (1993) Phenotypically diverse mouse thymic stromal cell lines which induce proliferation and differentiation of hematopoietic cells. Eur. J. Immunol., 23:1201-1214.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 1201-1214
    • Faas, S.J.1    Rothstein, J.L.2    Kreider, B.L.3    Rovera, G.4    Knowles, B.B.5
  • 19
    • 0025728580 scopus 로고
    • Epithelial heterogeneity in the murine thymus: A cell surface glycoprotein expressed by subcapsular and medullary epithelium
    • Farr, A., Nelson, A., Truex, J., and Hosier, S. (1991) Epithelial heterogeneity in the murine thymus: A cell surface glycoprotein expressed by subcapsular and medullary epithelium. J. Histochem. Cytochem., 39:645-653.
    • (1991) J. Histochem. Cytochem. , vol.39 , pp. 645-653
    • Farr, A.1    Nelson, A.2    Truex, J.3    Hosier, S.4
  • 20
    • 0023839077 scopus 로고
    • The neurohormonal thymic microenvironment: Immunocytochemical evidence that thymic nurse cells are neuroendocrine cells
    • Geenen, V., Defresne, M.P., Robert, F., Legros, J.J., Franchimont, P., and Boniver, J. (1988) The neurohormonal thymic microenvironment: Immunocytochemical evidence that thymic nurse cells are neuroendocrine cells. Neuroendocrinology, 47:365-368.
    • (1988) Neuroendocrinology , vol.47 , pp. 365-368
    • Geenen, V.1    Defresne, M.P.2    Robert, F.3    Legros, J.J.4    Franchimont, P.5    Boniver, J.6
  • 22
    • 0025099642 scopus 로고
    • Establishment of a murine thymic epithelial cell line capable of inducing both nurse cell formation and thymocyte apoptosis
    • Hiramine, C., Hojo, K., Koseto, M., Nakagawa, T., and Mukasa, A. (1990) Establishment of a murine thymic epithelial cell line capable of inducing both nurse cell formation and thymocyte apoptosis. Lab. Invest., 62:41-54.
    • (1990) Lab. Invest. , vol.62 , pp. 41-54
    • Hiramine, C.1    Hojo, K.2    Koseto, M.3    Nakagawa, T.4    Mukasa, A.5
  • 23
    • 0023394488 scopus 로고
    • In vitro behavior of thymic nurse cell-like complexes from mechanically and enzymatically dissociated frog
    • Holtfreter, M.B., and Cohen, N. (1987) In vitro behavior of thymic nurse cell-like complexes from mechanically and enzymatically dissociated frog. Am. J. Anat., 179:342-355.
    • (1987) Am. J. Anat. , vol.179 , pp. 342-355
    • Holtfreter, M.B.1    Cohen, N.2
  • 25
    • 0023220987 scopus 로고
    • Thymic epithelial reticular cell subpopulations in mice defined by monoclonal antibodies
    • Kaneshima, H., Ito, M., Asai, J., Taguchi, O., and Hiai, H. (1987) Thymic epithelial reticular cell subpopulations in mice defined by monoclonal antibodies. Lab. Invest., 56:372-380.
    • (1987) Lab. Invest. , vol.56 , pp. 372-380
    • Kaneshima, H.1    Ito, M.2    Asai, J.3    Taguchi, O.4    Hiai, H.5
  • 26
    • 0019951119 scopus 로고
    • Lymphoepithelial interactions in the mouse thymus: Phenotypic and kinetic studies on thymic nurse cells
    • Kyewski, B.A., and Kaplan, H.S. (1982) Lymphoepithelial interactions in the mouse thymus: Phenotypic and kinetic studies on thymic nurse cells. J. Immunol., 128:2287-2294.
    • (1982) J. Immunol. , vol.128 , pp. 2287-2294
    • Kyewski, B.A.1    Kaplan, H.S.2
  • 27
    • 0342465018 scopus 로고
    • Thymocyte rosettes: Multicellular complexes of lymphocytes and bone marrow-derived stromal cells in the mouse thymus
    • Kyewski, B.A., Rouse, R.V., and Kaplan, H.S. (1982) Thymocyte rosettes: Multicellular complexes of lymphocytes and bone marrow-derived stromal cells in the mouse thymus. Proc. Natl. Acad. Sci. U. S. A.., 79:5646-5650.
    • (1982) Proc. Natl. Acad. Sci. U. S. A.. , vol.79 , pp. 5646-5650
    • Kyewski, B.A.1    Rouse, R.V.2    Kaplan, H.S.3
  • 28
    • 0021187030 scopus 로고
    • Intrathymic lymphopoesis: Stromal cell-associated proliferation of T cells is independent of lymphocyte phenotype
    • Kyewski, B.A., Travis, M., and Kaplan, H.S. (1984) Intrathymic lymphopoesis: Stromal cell-associated proliferation of T cells is independent of lymphocyte phenotype. J. Immunol., 133:1111-1119.
    • (1984) J. Immunol. , vol.133 , pp. 1111-1119
    • Kyewski, B.A.1    Travis, M.2    Kaplan, H.S.3
  • 29
    • 0024327233 scopus 로고
    • Antibody against the T cell receptor/CD3 complex interfere with distinct intra thymic cell-cell interactions in vivo: Correlation arrest of T cell differentiation
    • Kyewski, B.A., Schirrmacher, V., and Allison, J.P. (1989) Antibody against the T cell receptor/CD3 complex interfere with distinct intra thymic cell-cell interactions in vivo: Correlation arrest of T cell differentiation. Eur. J. Immunol., 19:857-863.
    • (1989) Eur. J. Immunol. , vol.19 , pp. 857-863
    • Kyewski, B.A.1    Schirrmacher, V.2    Allison, J.P.3
  • 30
    • 0024044105 scopus 로고
    • Lymphocyte depletion in thymic nurse cells: A tool to identify in situ lympho-epithelial complexes having thymic nurse cell characteristics
    • Leene, W., Waal-Malefijt, R. de, Roholl, P.J., and Hoeben, K.A. (1988) Lymphocyte depletion in thymic nurse cells: A tool to identify in situ lympho-epithelial complexes having thymic nurse cell characteristics. Cell Tissue Res., 253:61-68.
    • (1988) Cell Tissue Res. , vol.253 , pp. 61-68
    • Leene, W.1    De Waal-Malefijt, R.2    Roholl, P.J.3    Hoeben, K.A.4
  • 31
    • 0026602555 scopus 로고
    • Thymic nurse cells exclusively bind and internalize CD4+CD8+ thymocytes
    • Li, Y., Pezzano, M., Philp, D., Reid, V., and Guyden, J. (1992) Thymic nurse cells exclusively bind and internalize CD4+CD8+ thymocytes. Cell. Immunol., 140:495-506.
    • (1992) Cell. Immunol. , vol.140 , pp. 495-506
    • Li, Y.1    Pezzano, M.2    Philp, D.3    Reid, V.4    Guyden, J.5
  • 32
    • 0024492493 scopus 로고
    • Thymic cortical epithelial cells can present self-antigens in vivo
    • Lorenz, R.G., and Allen, P.M. (1989) Thymic cortical epithelial cells can present self-antigens in vivo. Nature, 337:560-562.
    • (1989) Nature , vol.337 , pp. 560-562
    • Lorenz, R.G.1    Allen, P.M.2
  • 33
    • 0025924176 scopus 로고
    • Production of prostoglandin E2 and prostacyclin by thymic nurse cells in culture
    • McCormack, J.E., Kappler, J., Marrack, P., and Westcott, J.Y. (1991a) Production of prostoglandin E2 and prostacyclin by thymic nurse cells in culture. J. Immunol., 146:239-243.
    • (1991) J. Immunol. , vol.146 , pp. 239-243
    • McCormack, J.E.1    Kappler, J.2    Marrack, P.3    Westcott, J.Y.4
  • 35
    • 0025668707 scopus 로고
    • Thymic stromal cell clone with nursing activity supports the growth and differentiation of murine CD4+8+ thymocytes in vitro
    • Nishimura, T., Takeuchi, Y., Ichimura, Y., Gao, X.H., Akatsuka, A., Tamaoki, N., Yagita, H., Okumura, K., and Habu, S. (1990) Thymic stromal cell clone with nursing activity supports the growth and differentiation of murine CD4+8+ thymocytes in vitro. J. Immunol., 145:4012-4017.
    • (1990) J. Immunol. , vol.145 , pp. 4012-4017
    • Nishimura, T.1    Takeuchi, Y.2    Ichimura, Y.3    Gao, X.H.4    Akatsuka, A.5    Tamaoki, N.6    Yagita, H.7    Okumura, K.8    Habu, S.9
  • 36
    • 0027216160 scopus 로고
    • The binding, internalization and release of thymocytes by thymic nurse cells
    • Philp, D., Pezzano, M., Li, Y., Omene, C., Boto, W., and Guyden, J. (1993) The binding, internalization and release of thymocytes by thymic nurse cells. Cell. Immunol., 148:301-315.
    • (1993) Cell. Immunol. , vol.148 , pp. 301-315
    • Philp, D.1    Pezzano, M.2    Li, Y.3    Omene, C.4    Boto, W.5    Guyden, J.6
  • 38
    • 0027418383 scopus 로고
    • In situ analyses of in ovo graft-vs.-host reaction induced by thymic nurse cell lymphocytes
    • Rieker, T., Penninger, J., Hala, K., Cooper, M.D., and Wick, G. (1993) In situ analyses of in ovo graft-vs.-host reaction induced by thymic nurse cell lymphocytes. Eur. J. Immunol., 23:904-910.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 904-910
    • Rieker, T.1    Penninger, J.2    Hala, K.3    Cooper, M.D.4    Wick, G.5
  • 39
    • 0019520361 scopus 로고
    • The human thymus microenvironment: In vivo identification of thymic nurse cells and other antigenically-distinct subpopulations of epithelial cells
    • Ritter, M.A., Sauvage, C.A., and Cotmore, S.F. (1981) The human thymus microenvironment: In vivo identification of thymic nurse cells and other antigenically-distinct subpopulations of epithelial cells. Immunology, 44:439-446.
    • (1981) Immunology , vol.44 , pp. 439-446
    • Ritter, M.A.1    Sauvage, C.A.2    Cotmore, S.F.3
  • 40
    • 0024270586 scopus 로고
    • Monoclonal antibodies reactive with subsets of mouse and human thymic epithelial cells
    • Rouse, R.V., Bolin, L.M., Bender, J.R., and Kyewski, B.A. (1988) Monoclonal antibodies reactive with subsets of mouse and human thymic epithelial cells. J. Histochem. Cytochem., 36:1511-1517.
    • (1988) J. Histochem. Cytochem. , vol.36 , pp. 1511-1517
    • Rouse, R.V.1    Bolin, L.M.2    Bender, J.R.3    Kyewski, B.A.4
  • 41
    • 0025367038 scopus 로고
    • Thymic nurse cells: Morphological study during their isolation from murine thymus
    • Toussaint-Demylle, D., Scheiff, J.M., and Haumont, S. (1990) Thymic nurse cells: Morphological study during their isolation from murine thymus. Cell Tissue Res., 261:115-123.
    • (1990) Cell Tissue Res. , vol.261 , pp. 115-123
    • Toussaint-Demylle, D.1    Scheiff, J.M.2    Haumont, S.3
  • 42
    • 0027309511 scopus 로고
    • Thymic nurse cells in culture: Morphological and antigenic characterization
    • Toussaint-Demylle, D., Scheiff, J.M., and Haumont S. (1993) Thymic nurse cells in culture: Morphological and antigenic characterization. Cell Tissue Res., 272:343-354.
    • (1993) Cell Tissue Res. , vol.272 , pp. 343-354
    • Toussaint-Demylle, D.1    Scheiff, J.M.2    Haumont, S.3
  • 43
    • 0022502672 scopus 로고
    • A scanning electron-microscopic study of the rat thymus with special reference to cell types and migration of lymphocytes into the general circulation
    • Ushiki, T. (1986) A scanning electron-microscopic study of the rat thymus with special reference to cell types and migration of lymphocytes into the general circulation. Cell Tissue Res., 244:285-298.
    • (1986) Cell Tissue Res. , vol.244 , pp. 285-298
    • Ushiki, T.1
  • 44
    • 0020675034 scopus 로고
    • Demonstration of keratin filaments in thymic nurse cells (TNC) and alloreactivity of TNC-T cell population
    • Vakharia, D.D. (1983) Demonstration of keratin filaments in thymic nurse cells (TNC) and alloreactivity of TNC-T cell population. Thymus, 5:43-52.
    • (1983) Thymus , vol.5 , pp. 43-52
    • Vakharia, D.D.1
  • 45
    • 0021269879 scopus 로고
    • Thymic epithelial cells derived from the cultures of thymic nurse cells
    • Vakharia, D.D., and Mitchison, N.A. (1984) Thymic epithelial cells derived from the cultures of thymic nurse cells. Immunol. Lett., 7:261-266.
    • (1984) Immunol. Lett. , vol.7 , pp. 261-266
    • Vakharia, D.D.1    Mitchison, N.A.2
  • 48
    • 0024233059 scopus 로고
    • Cell surface topography of thymic microenvironments
    • van Ewijk, W. (1988) Cell surface topography of thymic microenvironments. Lab. Invest., 59:579-590.
    • (1988) Lab. Invest. , vol.59 , pp. 579-590
    • Van Ewijk, W.1
  • 49
  • 52
    • 0024796863 scopus 로고
    • Analysis of the distribution of thymic epithelial microenvironmental molecules by immuno-electron microscopy
    • von Gaudecker, B., Larche, M., Schuurman, H.J., and Ritter, M.A. (1989) Analysis of the distribution of thymic epithelial microenvironmental molecules by immuno-electron microscopy. Thymus. 13:187-194.
    • (1989) Thymus , vol.13 , pp. 187-194
    • Von Gaudecker, B.1    Larche, M.2    Schuurman, H.J.3    Ritter, M.A.4
  • 53
    • 0018876548 scopus 로고
    • Thymic nurse cells-Ia-bearing epithelium involved in T lymphocyte differentiation?
    • Wekerle, H., and Ketelsen, U.P. (1980a) Thymic nurse cells-Ia-bearing epithelium involved in T lymphocyte differentiation? Nature 283: 402-404.
    • (1980) Nature , vol.283 , pp. 402-404
    • Wekerle, H.1    Ketelsen, U.P.2
  • 54
    • 0019273801 scopus 로고
    • Thymic nurse cells-intraepithelial microenvironment involved in thymic T cell differentiation?
    • Wekerle, H., and Ketelsen, U.P. (1980b) Thymic nurse cells-intraepithelial microenvironment involved in thymic T cell differentiation? Behring Inst. Mitt., 67:169-175.
    • (1980) Behring Inst. Mitt. , vol.67 , pp. 169-175
    • Wekerle, H.1    Ketelsen, U.P.2
  • 55
    • 0018818341 scopus 로고
    • Thymic nurse cells. Lymphoepithelial cell complexes in murine thymuses: Morphological and serological characterization
    • Wekerle, H., Ketelsen, U.P., and Ernst, M. (1980) Thymic nurse cells. Lymphoepithelial cell complexes in murine thymuses: Morphological and serological characterization. J. Exp. Med., 151:925-944.
    • (1980) J. Exp. Med. , vol.151 , pp. 925-944
    • Wekerle, H.1    Ketelsen, U.P.2    Ernst, M.3
  • 56
    • 0022517143 scopus 로고
    • Thymic nurse cells: A school for alloreactive and autoreactive cortical thymocytes?
    • Wick, G., and Oberhuber, G. (1986) Thymic nurse cells: A school for alloreactive and autoreactive cortical thymocytes? Eur. J. Immunol., 16:855-858.
    • (1986) Eur. J. Immunol. , vol.16 , pp. 855-858
    • Wick, G.1    Oberhuber, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.