Risperidone in the elderly: A pharmacoepidemiologic study

Journal of Clinical Psychiatry

Volumn 58, Issue 7, 1997, Pages 311-317

  Zarate Jr , Carlos A ^a,b,c   Baldessarini, Ross J ^a,b,c,d   Siegel, Arthur J ^a   Nakamura, Ataru ^b,c   McDonald, Jane ^a   Muir Hutchinson, Lou Ann ^a   Cherkerzian, Tanya ^b   Tohen, Mauricio ^a,b,c,e  

^a Pharmacy and Therapeutics Committee   (United States)

^b MCLEAN HOSPITAL   (United States)

^c Consolidated Dept of Psychiatry ^*  (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZATROPINE; BENZATROPINE MESILATE; CARBAMAZEPINE; CLONAZEPAM; GLIBENCLAMIDE; LEVOTHYROXINE; LEVOTHYROXINE SODIUM; LORAZEPAM; METOPROLOL; METOPROLOL TARTRATE; NIFEDIPINE; OXYBUTYNIN; PAROXETINE; PHENYTOIN; PSYCHOTROPIC AGENT; RANITIDINE; RISPERIDONE; SEROTONIN UPTAKE INHIBITOR; TRAZODONE; VALPROATE SEMISODIUM; VALPROIC ACID;

AFFECTIVE NEUROSIS; AGED; AGITATION; ARTICLE; DRUG EFFICACY; DRUG INDICATION; DRUG TOLERABILITY; ELDERLY CARE; EXTRAPYRAMIDAL SYMPTOM; FATALITY; FEMALE; GERONTOPSYCHIATRY; HEART ARREST; HUMAN; HYPOTENSION; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD; PHARMACOEPIDEMIOLOGY; PRIORITY JOURNAL; PSYCHOSIS;

EID: 1842339932     PISSN: 01606689     EISSN: None     Source Type: Journal    
DOI: 10.4088/JCP.v58n0705     Document Type: Article

References (31)

1. Devanand DP, Levy SR. Neuroleptic treatment of agitation and psychosis in dementia. J Geriatr Psychiatry Neurol 1995;8(suppl 1):S18-S27
2. Peabody CA, Warner MD, Whiteford HA, et al. Neuroleptics and the elderly. J Am Geriatr Soc 1987;35:233-238
3. Baldessarini RJ. Chemotherapy in Psychiatry: Principles and Practice. 2nd ed. Cambridge, Mass: Harvard University Press; 1985
4. Baldessarini RJ. Drugs and the treatment of psychiatric disorders. In: Harden W, Rudin W, Molinoff PB, et al, eds. Goodman and Gilman's The Pharmacologic Basis of Therapeutics. 9th ed. New York, NY: McGraw-Hill; 1996:399-459
5. Blumenthal MD, Davie JW. Dizziness and falling in elderly psychiatric outpatients. Am J Psychiatry 1980;137:203-206
6. Ray WA, Griffin MR, Schaffner W, et al. Psychotropic drug use and the risk of hip fracture. N Engl J Med 1987;316:363-369
7. Francis J Jr. Drug-induced delirium: diagnosis and treatment. CNS Drugs 1996;5:103-114
8. Raskind MA, Risse SC. Antipsychotic drugs and the elderly. J Clin Psychiatry 1986;47(5, suppl):17-22
9. Salz BL, Kane JM, Woemer MG, et al. Prospective study of tardive dyskinesia in the elderly. Psychopharmacol Bull 1989;25:52-56
10. Avorn J, Monane M, Everitt DE, et al. Clinical assessment of extrapyramidal signs in nursing home patients given antipsychotic medication. Arch Intern Med 1994;154:1113-1117
11. Marder SR, Meibach RC. Risperidone in the treatment of schizophrenia. Am J Psychiatry 1994;51:825-835
12. Aronson SM, Lingam VS, Hasanat KA. Risperidone in geropsychiatry: review of experience in two teaching public hospitals. In: New Research Program and Abstracts of the 148th Annual Meeting of the American Psychiatric Association; May 23, 1995; Miami, Fla. Abstract NR267:127
13. Berman I, Pavlov-Rachov J, Losonczy MF, et al. Risperidone in elderly schizophrenic patients. In: Abstracts of the 34th Annual Meeting of the New Clinical Drug Evaluation Unit; May 30-June 2, 1994; Orlando, Fla. Poster Abstract 57
14. Borison RL, Davidson M, Berman I. Risperidone treatment in elderly patients with schizophrenia or dementia. In: Abstracts of the 46th Annual Meeting of the Institute of Hospital and Community Psychiatry; May 6-12, 1995; Philadelphia, Pa. Poster Abstract 51
15. Goldberg RJ, Goldberg JS. Low-dose risperidone for dementia-related disturbed behavior in nursing homes. In: New Research Program and Abstracts of the 148th Annual Meeting of the American Psychiatric Association; May 23, 1995; Miami, Fla. Abstract NR262:126
16. Prado N, Kramer-Ginsberg E, Kremen N, et al. Risperidone in dementia with behavioral disturbances. In: New Research Program and Abstracts of the 148th Annual Meeting of the American Psychiatric Association; May 22, 1995; Miami, Fla. Abstract NR6:55
17. Reyntjens A, Heylen S, Gelders Y. Risperidone in the treatment of behavioral symptoms in psychogeriatric patients: a pilot clinical investigation [abstract]. Psychopharmacology 1988;96(1, suppl):335
18. Madhusoodanan S, Brenner R, Araujo L, et al. Efficacy of risperidone treatment for psychoses associated with schizophrenia, schizoaffective disorder, bipolar disorder, or senile dementia in 11 geriatric patients: a case series. J Clin Psychiatry 1995;56:514-518
19. Stanton SP, Wilson DR, Keck PE Jr, et al. Clinical predictors of acute risperidone response in elderly patients with schizophrenia and schizoaffective illnesses. In: New Research Program and Abstracts of the 149th Annual Meeting of the American Psychiatric Association; May 6, 1996; New York, NY. Abstract NR117:99
20. Joshi UP, Joshi PM. Risperidone in geriatric patients with chronic psychoses and concurrent medical illnesses. In: New Research Program and Abstracts of the 149th Annual Meeting of the American Psychiatric Association; May 7, 1996; New York, NY. Abstract NR387:173
21. Aronson SM, Lingam VS, Hasanat KA. Risperidone in the treatment of elderly psychiatric patients. In: New Research Program and Abstracts of the 149th Annual Meeting of the American Psychiatric Association; May 8, 1996; New York, NY. Abstract NR493:204
22. Jeanblanc W, Davis YB. Risperidone for treating dementia-associated aggression [letter]. Am J Psychiatry 1995;152:1239
23. Raheja RK, Bharwani I, Penetrante AE. Efficacy of risperidone for behavioral disorders in the elderly: a clinical observation. J Geriatr Psychiatry Neurol 1995;8:159-161
24. Jeste DV, Eastham JH, Lacro JP, et al. Management of late-life psychosis. J Clin Psychiatry 1996;57(suppl 3):39-45
25. Risperdal (risperidone). Physicians' Desk Reference. 50th ed. Montvale, NJ: Medical Economics; 1996:1301-1305
26. Guy W. Clinical Global Impression. In: Guy W. ECDEU Assessment Manual for Psychopharmacology. US Dept Health, Education, and Welfare publication (ADM)76-338. Rockville, Md: National Institute of Mental Health; 1976:218-222
27. Banov MD, Zarate CA Jr, Tohen M, et al. Clozapine therapy in refractory affective disorders: polarity predicts response in long-term follow-up. J Clin Psychiatry 1994;55:295-300
28. Continuous Quality Improvement update: teaming up to improve patient care quality. McLean This Week 1995; Mar 24:1-2
29. Meyer M, Baldessarini RJ, Goff D, et al. Clinically significant interactions of psychotropic drugs with antipsychotic agents. Drug Saf. In press
30. Baldessarini RJ, Teicher MH. Dosing of antipsychotic agents in pediatric populations. Journal of Child and Adolescent Psychopharmacology 1995; 5:1-4
31. Gupta J, Black DW, Smith DA. Risperidone: review of its pharmacology and therapeutic use in schizophrenia. Ann Clin Psychiatry 1994;6: 173-180