Anticarrier immunity suppresses the antibody response to polysaccharide antigens after intranasal immunization with the polysaccharide-protein conjugate

Infection and Immunity

Volumn 65, Issue 5, 1997, Pages 1579-1583

  Bergquist, Charlotta ^a   Lagergård, Teresa ^a   Holmgren, Jan ^a,b  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b Department for Medical Microbiology ^*  (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL POLYSACCHARIDE; CHOLERA TOXIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; IMMUNIZATION; INFECTION RESISTANCE; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; PRIORITY JOURNAL; VIBRIO CHOLERAE;

EID: 1842336912     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.65.5.1579-1583.1997     Document Type: Article

References (34)

1. Acharya, I. L., C. V. Lowe, R. Thapa, V. L. Gurubacharya, M. B. Schrestha, M. Cadoz, D. Schultz, J. Armand, D. A. Bryla, B. Trollfors, T. Cramton, R. Schneerson, and J. B. Robbins. 1987. Prevention of typhoid fever in Nepal with the Vi capsular polysaccharide of Salmonella typhi. N. Engl. J. Med. 317:1101-1104.
2. Aizpurua, H. J., and G. J. Russell-Jones. 1988. Oral vaccination. Identification of classes of proteins that provoke an immune response upon oral feeding. J. Exp. Med. 167:440-451.
3. Anderson, P., R. B. Johnston, Jr., and D. H. Smith. 1972. Human serum activities against Haemophilus influenzae type B. J. Clin. Invest. 51:31-38.
4. Attridge, S. 1991. Oral immunization with Salmonella typhi Ty21a-based clones expressing Vibrio cholerae O-antigen: serum bactericidal antibody responses in man in relation to pre-immunization antibody levels. Vaccine 9:877-882.
5. Avery, O. T., and W. F. Goebel. 1931. Chemo-immunological studies on conjugated carbohydrate proteins. V. The immunological specificity of an antigen prepared by combining the capsular polysaccharide of type III Pneumococcus with foreign protein. J. Exp. Med. 54:437-447.
6. Barbour, M. L., R. T. Mayon-White, C. Coles, D. W. M. Crook, and E. R. Moxon. 1995. The impact of conjugate vaccine on carriage rate of Haemophilus influenzae type b. J. Infect. Dis. 171:93-98.
7. Barington, T., M. Skettrup, L. Juul, and C. Heilmann. 1993. Non-epitope-specific suppression of the antibody response to Haemophilus influenzae type b conjugate vaccines by preimmunization with vaccine components. Infect. Immun. 61:432-438.
8. Bergquist, C., T, Lagergård, M. Lindblad, and J. Holmgren. 1995. Local and systemic antibody responses to dextran-cholera toxin B subunit conjugates. Infect. Immun. 63:2021-2025.
9. Black, R. E., M. M. Levine, M. L. Clements, C. R. Young, A.-M. Svenner-holm, and J. Holmgren. 1987. Protective efficacy in humans of killed whole-Vibrio oral cholera vaccine with and without the B subunit of cholera toxin. Infect. Immun. 55:1116-1120.
10. Brandtzaeg, P. 1995. Immunocompetent cells of the upper airway: functions in normal and diseased mucosa. Eur. Arch. Otorhinolaryngol. 252S:S8-S21.
11. Cantey, J. R. 1978. Prevention of bacterial infections of mucosal surfaces by immune secretory IgA. Adv. Exp. Med. Biol. 107:461-470.
12. Czerkinsky, C., M. W. Russell, N. Lycke, M. Lindblad, and J. Holmgren. 1989. Oral administration of a streptococcal antigen coupled to cholera toxin B subunit evokes strong antibody responses in salivary glands and extramucosal tissues. Infect. Immun. 57:1072-1077.
13. Fattom, A., C. Lue, S. C. Szu, J. Mestecky, G. Schiffman, D. Bryla, W. F. Vann, D. Watson, L. M. Kimzey, J. B. Robbins, and R. Schneerson. 1990. Serum antibody responses in adult volunteers elicited by injection of Streptococcus pneumoniae type 12F polysaccharide alone or conjugated to diphtheria toxoid. Infect. Immun. 58:2309-2312.
14. Fattom, A. R. Schneerson, S. C. Szu, W. F. Vann, J. Shiloach, W. W. Karakawa, and J. B. Robbins. 1990. Synthesis and immunological properties in mice of vaccines composed of Staphylococcus aureus type 5 and type 8 capsular polysaccharides conjugated to Pseudomonas aeruginosa exotoxin A. Infect. Immun. 58:2367-2374.
15. Granoff, D. M., S. J. Holmes, R. B. Belshe, M. T. Osterholm, J. E. McHugh, and E. L. Andersson. 1994. Effect of carrier protein priming on antibody responses to Haemophilus influenzae type b conjugate vaccines in infants. JAMA 272:1116-1121.
16. Holmgren, J. 1981. Actions of cholera toxin and the prevention and treatment of cholera. Nature 292:413-417.
17. Kauppi, M., L. Saarinen, and H. Käyty. 1993. Anti-capsular polysaccharide antibodies reduce nasopharyngeal colonization by Haemophilus influenzae type b in infant rats. J. Infect. Dis. 167:365-371.
18. Lagergård, T., J. Shiloach, J. B. Robbins, and R. Schneerson. 1990. Synthesis and immunological properties of conjugates composed of group B streptococcus type III capsular polysaccharide covalently bound to tetanus toxoid. Infect. Immun. 58:687-694.
19. Lebens, M., S. Johansson, J. Osek, M. Lindblad, and J. Holmgren. 1993. Large-scale production of Vibrio cholerae toxin B subunit for use in oral vaccines. Bio/technology 11:1574-1578.
20. Liang, X., M. E. Lamm, and J. G. Nedrud. 1988. Oral administration of cholera toxin-Sendai virus conjugate potentiates gut and respiratory immunity against Sendai virus. J. Immunol. 141:1495-1501.
21. Lycke, N., and J. Holmgren. 1986. Strong adjuvant properties of cholera toxin on gut mucosal immune responses to orally presented antigens. Immunology 59:301-308.
22. Menge, A. C. S. M. Michalek, M. W. Russell, and J. Mestecky. 1993. Immune response of the female rat genital tract after oral and local immunization with keyhole limpet hemocyanin conjugated to the cholera toxin B subunit. Infect. Immun. 61:2162-2171.
23. Quiding-Järbrink, M., G. Granström, I. Nordström, J. Holmgren, and C. Czerkinsky. 1995. Induction of compartmentalized B-cell responses in the human tonsils. Infect. Immun. 63:853-857.
24. Rask, C. Personal communication.
25. Richman, D. D., B. R. Murphy, R. M. Chanock, J. M. Gwaltney, Jr., R. G. Douglas, R. F. Bretts, N. R. Blacklow, F. B. Rose, T. A. Parrina, M. M. Levine, and E. S. Caplan. 1976. Temperature-sensitive mutants of influenza A virus. XII. Safety, antigenicity, transmissibility and efficacy of influenza A/Udorn/72-ts-lE recombinant viruses in human adults. J. Infect. Dis. 167: 584-592.
26. Russell, M. W., Z. Moldoveanu, P. L. White, G. J. Sibert, J. Mestecky, and S. M. Michalek. 1996. Salivary, nasal, genital and systemic antibody responses in monkeys immunized intranasally with a bacterial protein antigen and the cholera toxin B subunit. Infect. Immun. 64:1272-1283.
27. Sarvas, H., S. Kurikka, I. J. T. Seppälä, P. H. Mäkelä, and O. Mäkelä. 1992. Maternal antibodies partly inhibit an active antibody response to routine tetanus toxoid immunization in infants. J. Infect. Dis. 165:977-979.
28. Schneerson, R., O. Barrera, A. Sutton, and J. B. Robbins. 1980. Preparation, characterization and immunogenicity of Haemophilus influenzae type b polysaccharide-protein conjugates. J. Exp. Med. 152:361-376.
29. Spiro, R. G. 1966. Analysis of sugar found on glycoproteins. Determination of neutral sugars. Methods Enzymol. 8:4.
30. Svennerholm, A.-M., and J. Holmgren. 1978. Identification of Escherichia coli heat labile enterotoxin by means of a ganglioside immunosorbent assay (GM1 ELISA) procedure. Curr. Microbiol. 1:19-23.
31. Szu, S. C., D. N. Taylor, A. C. Trofa, J. D. Clements, J. Shiloach, J. C. Sadoff, D. A. Bryla, and J. B. Robbins. 1994. Laboratory and preliminary clinical characterization of Vi capsular polysaccharide-protein conjugate vaccines. Infect. Immun. 62:4440-4444.
32. Tamura, S., H. Asanuma, T. Tomita, K. Komse, K. Kawahara, H. Danbara, N. Hattori, K. Wattanabe, Y. Suzuki, T. Nagamine, C. Aizawa, A. Oya, and T. Kurata. 1994. Escherichia coli heat-labile enterotoxin B subunits supplemented with a trace amount of holotoxin as an adjuvant for nasal influenza vaccine. Vaccine 12:1083-1089.
33. van Alphen, L., P. Eijk, H. Käyhty, J. van Marle, and J. Dankert. 1996. Antibodies to Haemophilus influenzae type b polysaccharide affect bacterial adherence and multiplication. Infect. Immun. 64:995-1001.
34. Walsh, T. E., and P. R. Cannon. 1938. Immunization of the respiratory tract. A comparative study of the antibody content of the respiratory and other tissues following active, passive and regional immunization. J. Immunol. 35:31-46.