Neurologic findings in vitamin E deficiency

American Family Physician

Volumn 55, Issue 1, 1997, Pages 197-201

  Mahlon Tanyel, Mary C ^a   Mancano, Louis D ^a  

^a Montgomery Family Practice Residency Program   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL;

ABETALIPOPROTEINEMIA; ADULT; ALPHA TOCOPHEROL DEFICIENCY; CASE REPORT; CHOLESTASIS; CYSTIC FIBROSIS; HUMAN; INTESTINE ATRESIA; INTESTINE SURGERY; MALABSORPTION; MALE; MUSCLE WEAKNESS; NEUROLOGIC DISEASE; NEUROLOGICAL COMPLICATION; ORAL DRUG ADMINISTRATION; REVIEW; SHORT BOWEL SYNDROME; VITAMIN BLOOD LEVEL; VITAMIN DEFICIENCY;

ADULT; CHOLESTASIS; CYSTIC FIBROSIS; HUMANS; MALE; NERVOUS SYSTEM DISEASES; SHORT BOWEL SYNDROME; SYNDROME; VITAMIN E; VITAMIN E DEFICIENCY;

EID: 1842330948     PISSN: 0002838X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (15)

1. Sokol RJ. Vitamin E and neurologic deficits. Adv Pediatr 1990;37:119-48.
2. Meydani M. Vitamin E. Lancet 1995;345:170-5.
3. Bjorneboe A, Bjorneboe GE, Drevon CA. Absorption, transport and distribution of vitamin E. J Nutr 1990;120:233-42.
4. Kayden HJ, Traber MG. Absorption, lipoprotein transport, and regulation of plasma concentrations of vitamin E in humans. J Lipid Res 1993;34:343-58.
5. Cutler R. Metabolic and nutritional disorders: neurologic disorders resulting from vitamin deficiency. Sci Am 1990:11(7):1-4.
6. Cynamon HA, Milov DE, Valenstein E, Wagner M. Effect of vitamin E deficiency on neurologic function in patients with cystic fibrosis. J Pediatr 1988;113:637-40.
7. Morrow MJ. Neurologic complications of vitamin E deficiency: case report and review of the literature. Bull Clin Neurosci 1985;50:53-60.
8. Gotoda T, Arita M, Arai H, Inoue K, Yokota T, Fukuo Y, et al. Adult-onset spinocerebellar dysfunction caused by a mutation in the gene for the alpha-tocopherol-transfer protein. N Engl J Med 1995;333:1313-8.
9. Rayner RJ, Doran R, Roussounis SH. Isolated vitamin E deficiency and progressive ataxia. Arch Dis Child 1993;69:602-3.
10. Ouahchi K, Arita M, Kayden H, Hentati F, Ben Hamida M, Sokol R, et al. Ataxia with isolated vitamin E deficiency is caused by mutations in the alpha-tocopherol transfer protein. Nat Genet 1995;9:141-5.
11. Doerflinger N, Under C, Ouahchi K, Gyapay G, Weissenbach J, Le Paslier D, et al. Ataxia with vitamin E deficiency: refinement of genetic localization and analysis of linkage disequilibrium by using new markers in 14 families. Am J Hum Genet 1995;56:1116-24.
12. Ben Hamida M, Belal S, Sirugo G, Ben Hamida C, Panayides K, Ionannou F, et al. Friedreich's ataxia phenotype not linked to chromosome 9 and associated with selective autosomal recessive vitamin E deficiency in two inbred Tunisian families. Neurology 1993;43:2179-83.
13. Ben Hamida C, Doerflinger N, Belal S, Linder C, Reutenauer L, Dib C, et al. Localization of Friedreich ataxia phenotype with selective vitamin E deficiency to chromosome 8q by homozygosity mapping. Nat Genet 1993;5:195-200.
14. Sokol RJ, Guggenheim MA, Heubi JE, Iannaccone ST, Butler-Simon N, Jackson V, et al. Frequency and clinical progression of the vitamin E deficiency neurologic disorder in children with prolonged neonatal cholestasis. Am J Dis Child 1985;139:1211-5.
15. Sokol RJ, Butler-Simon N, Conner C, Heubi JE, Sinatra FR, Suchy FJ, et al. Multicenter trial of d-alpha-tocopheryl polyethylene glycol 1000 succinate for treatment of vitamin E deficiency in children with chronic cholestasis. Gastroenterology 1993;104:1727-35.