메뉴 건너뛰기




Volumn 29, Issue 1, 1997, Pages 16-27

Effects of the DNA topoisomerase II inhibitor merbarone in male mouse meiotic divisions in vivo: Cell cycle arrest and induction of aneuploidy

Author keywords

Aneuploidy; Cell cycle arrest; CREST; Merbarone; Micronuclei; Spermatogenesis

Indexed keywords

DNA TOPOISOMERASE (ATP HYDROLYSING); ETOPOSIDE; MERBARONE;

EID: 1842328032     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2280(1997)29:1<16::AID-EM3>3.0.CO;2-B     Document Type: Article
Times cited : (49)

References (42)
  • 1
    • 0025966711 scopus 로고
    • Chromosome assembly in vitro: Topoisomerase II is required for condensation
    • Adachi Y, Luke M, and Laemmli UK (1991): Chromosome assembly in vitro: topoisomerase II is required for condensation. Cell 64:137-148.
    • (1991) Cell , vol.64 , pp. 137-148
    • Adachi, Y.1    Luke, M.2    Laemmli, U.K.3
  • 2
    • 0028122271 scopus 로고
    • Mutagenicity and carcinogenicity of topoisomerase-interactive agents
    • Anderson RD, Berger NA (1994): Mutagenicity and carcinogenicity of topoisomerase-interactive agents. Mutat Res 309:109-142.
    • (1994) Mutat Res , vol.309 , pp. 109-142
    • Anderson, R.D.1    Berger, N.A.2
  • 3
    • 0028030324 scopus 로고
    • Novel inhibitors of DNA topoisomerase II in drug-resistant tumor cells
    • Beck WT, Kim R, Chen M (1994): Novel inhibitors of DNA topoisomerase II in drug-resistant tumor cells. Cancer Chemother Pharmacol 34 suppl:14-18.
    • (1994) Cancer Chemother Pharmacol , vol.34 , Issue.SUPPL. , pp. 14-18
    • Beck, W.T.1    Kim, R.2    Chen, M.3
  • 4
    • 0021871841 scopus 로고
    • 5-(N-phenylcarboxamido)-2-thiobarbituric acid (NSC-336628), a novel potential antitumor agent
    • Brewer AD, Minatelli JA., Plowman J, Paoull KD, Narayanan VL (1985): 5-(N-phenylcarboxamido)-2-thiobarbituric acid (NSC-336628), a novel potential antitumor agent. Biochem Pharmacol 34:2047-2050.
    • (1985) Biochem Pharmacol , vol.34 , pp. 2047-2050
    • Brewer, A.D.1    Minatelli, J.A.2    Plowman, J.3    Paoull, K.D.4    Narayanan, V.L.5
  • 5
    • 0021749639 scopus 로고
    • Nonintercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II
    • Chen GL, Yang L, Rowe TC, Halligan BD, Tewey KM, Liu LF (1984): Nonintercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II. J Biol Chem 259:13560-13566.
    • (1984) J Biol Chem , vol.259 , pp. 13560-13566
    • Chen, G.L.1    Yang, L.2    Rowe, T.C.3    Halligan, B.D.4    Tewey, K.M.5    Liu, L.F.6
  • 6
    • 0027140482 scopus 로고
    • Teniposide-resistant CEM cells, which express mutant DNA topoisomerase II, when treated with non-complex-stabilizing inhibitors of the enzyme, display no cross-resistance and reveal aberrant functions of the mutant enzyme
    • Chen M, Beck WT (1993): Teniposide-resistant CEM cells, which express mutant DNA topoisomerase II, when treated with non-complex-stabilizing inhibitors of the enzyme, display no cross-resistance and reveal aberrant functions of the mutant enzyme. Cancer Res 53:5946-5953.
    • (1993) Cancer Res , vol.53 , pp. 5946-5953
    • Chen, M.1    Beck, W.T.2
  • 7
    • 0028933380 scopus 로고
    • 2 arrest by DNA topoisomerase II inhibitors merbarone and VM-26
    • 2 arrest by DNA topoisomerase II inhibitors merbarone and VM-26. Cancer Res 55:1509-1516.
    • (1995) Cancer Res , vol.55 , pp. 1509-1516
    • Chen, M.1    Beck, W.T.2
  • 8
    • 0027209306 scopus 로고
    • Topoisomerase II inhibition prevents anaphase chromatid segregation in mammalian cells independently of the generation of DNA strand breaks
    • Clarke DJ, Johnson RT, Downes CS (1993): Topoisomerase II inhibition prevents anaphase chromatid segregation in mammalian cells independently of the generation of DNA strand breaks. J Cell Sci 105:563-569.
    • (1993) J Cell Sci , vol.105 , pp. 563-569
    • Clarke, D.J.1    Johnson, R.T.2    Downes, C.S.3
  • 9
    • 0002406825 scopus 로고
    • Duration of the cycle of the seminiferous epithelium of normal and hypophysectomized and hypophysectomized-hormone treated albino rats
    • Clermont Y, Harvey SC (1965): Duration of the cycle of the seminiferous epithelium of normal and hypophysectomized and hypophysectomized-hormone treated albino rats. Endocrinology 76:80-89.
    • (1965) Endocrinology , vol.76 , pp. 80-89
    • Clermont, Y.1    Harvey, S.C.2
  • 11
    • 0025938867 scopus 로고
    • Inhibitors of DNA topoisomerase II prevent chromatid separation in mammalian cells but do not prevent exit from mitosis
    • Downes CS, Mullinger AM, Johnson RT (1991): Inhibitors of DNA topoisomerase II prevent chromatid separation in mammalian cells but do not prevent exit from mitosis. Proc Natl Acad Sci USA 88:8895-8899.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 8895-8899
    • Downes, C.S.1    Mullinger, A.M.2    Johnson, R.T.3
  • 15
    • 0028329736 scopus 로고
    • Cell cycle progression and chromosome separation in mammalian cells cultured in the presence of the topoisomerase II inhibitors ICRF-187 [(+)-1,2-bis(dioxopiperazinyl-1-yl)propane; ADR-529] and ICRF-159 (razoxane)
    • Gorbsky GJ (1994): Cell cycle progression and chromosome separation in mammalian cells cultured in the presence of the topoisomerase II inhibitors ICRF-187 [(+)-1,2-bis(dioxopiperazinyl-1-yl)propane; ADR-529] and ICRF-159 (razoxane). Cancer Res 54:1042-1048.
    • (1994) Cancer Res , vol.54 , pp. 1042-1048
    • Gorbsky, G.J.1
  • 16
    • 0027303640 scopus 로고
    • Differential expression of a phosphoepitope at the kinetochores of moving chromosomes
    • Gorbsky GJ, Ricketts WA (1993): Differential expression of a phosphoepitope at the kinetochores of moving chromosomes. J Cell Biol 122:1311-1321.
    • (1993) J Cell Biol , vol.122 , pp. 1311-1321
    • Gorbsky, G.J.1    Ricketts, W.A.2
  • 17
    • 0027320782 scopus 로고
    • Cytokinetic differences in the action of N-[2-(dimethylamino)-ethyl]acridine-4-carboxamide as compared with that of amsacrine and doxorubicin
    • Haldane A, Holdaway KM, Finlay GJ, Baguley BC (1993): Cytokinetic differences in the action of N-[2-(dimethylamino)-ethyl]acridine-4-carboxamide as compared with that of amsacrine and doxorubicin. Cancer Chemother Pharmacol 32:463-470.
    • (1993) Cancer Chemother Pharmacol , vol.32 , pp. 463-470
    • Haldane, A.1    Holdaway, K.M.2    Finlay, G.J.3    Baguley, B.C.4
  • 18
    • 0000266944 scopus 로고
    • Differential expression of DNA topoisomerases I and II during the eukaryotic cell cycle
    • Heck MM, Hittelman WN, Earnshaw WC (1988): Differential expression of DNA topoisomerases I and II during the eukaryotic cell cycle. Proc Natl Acad Sci USA 85:1086-1090.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 1086-1090
    • Heck, M.M.1    Hittelman, W.N.2    Earnshaw, W.C.3
  • 19
    • 0029825966 scopus 로고    scopus 로고
    • Stage-specific apoptosis in the rat seminiferous epithelium: Quantification of irradiation effects
    • in press
    • Henriksén K, Kulmala J, Toppari J, Mehrotra K, Parvinen M (1996): Stage-specific apoptosis in the rat seminiferous epithelium: Quantification of irradiation effects. J Androl, in press.
    • (1996) J Androl
    • Henriksén, K.1    Kulmala, J.2    Toppari, J.3    Mehrotra, K.4    Parvinen, M.5
  • 20
    • 0027389490 scopus 로고
    • Topoisomerase II does not play a scaffolding role in the organization of mitotic chromosomes assembled in Xenopus egg extracts
    • Hirano T, Mitchison TJ (1993): Topoisomerase II does not play a scaffolding role in the organization of mitotic chromosomes assembled in Xenopus egg extracts. J Cell Biol 120:601-612.
    • (1993) J Cell Biol , vol.120 , pp. 601-612
    • Hirano, T.1    Mitchison, T.J.2
  • 22
    • 0027332904 scopus 로고
    • Analysis of micronuclei induced in mouse early spermatids by mitomycin C, vinblastine sulfate or etoposide using fluorescence in situ hybridization
    • Kallio M, Lähdetie J (1993): Analysis of micronuclei induced in mouse early spermatids by mitomycin C, vinblastine sulfate or etoposide using fluorescence in situ hybridization. Mutagenesis 8:561-567.
    • (1993) Mutagenesis , vol.8 , pp. 561-567
    • Kallio, M.1    Lähdetie, J.2
  • 23
    • 9544222713 scopus 로고    scopus 로고
    • Fragmentation of centromeric DNA and prevention of homologous chromosome separation in male mouse meiosis in vivo by the topoisomerase II inhibitor etoposide
    • Kallio M, Lähdetie J (1996): Fragmentation of centromeric DNA and prevention of homologous chromosome separation in male mouse meiosis in vivo by the topoisomerase II inhibitor etoposide. Mutagenesis 11:435-143.
    • (1996) Mutagenesis , vol.11 , pp. 435-1143
    • Kallio, M.1    Lähdetie, J.2
  • 24
    • 0028904251 scopus 로고
    • Effect of vinblastine and colchicine on male rat meiosis in vivo: Disturbances of spindle dynamics causing micronuclei and metaphase arrest
    • Kallio M, Sjöblom T, Löhdetie J (1995) Effect of vinblastine and colchicine on male rat meiosis in vivo: Disturbances of spindle dynamics causing micronuclei and metaphase arrest. Environ Mol Mutagen 25:106-117.
    • (1995) Environ Mol Mutagen , vol.25 , pp. 106-117
    • Kallio, M.1    Sjöblom, T.2    Löhdetie, J.3
  • 25
    • 0028872743 scopus 로고
    • Mitotic forces control a cell-cycle checkpoint
    • Li X, Nicklas RB (1995): Mitotic forces control a cell-cycle checkpoint. Nature 373:630-632.
    • (1995) Nature , vol.373 , pp. 630-632
    • Li, X.1    Nicklas, R.B.2
  • 26
    • 0021864097 scopus 로고
    • Single- and double-strand DNA breakage and repair in human lung adenocarcinoma cells exposed to etoposide and teniposide
    • Long BH, Musial ST, Brattain MG (1985): Single- and double-strand DNA breakage and repair in human lung adenocarcinoma cells exposed to etoposide and teniposide. Cancer Res 45:3106-3112.
    • (1985) Cancer Res , vol.45 , pp. 3106-3112
    • Long, B.H.1    Musial, S.T.2    Brattain, M.G.3
  • 27
    • 0028014665 scopus 로고
    • Preferential pericentric lesions and aneuploidy induced in mouse oocytes by the topoisomerase II inhibitor etoposide
    • Mailhes JB, Marchetti F, Phillips GL Jr, Barnhill, DR (1994): Preferential pericentric lesions and aneuploidy induced in mouse oocytes by the topoisomerase II inhibitor etoposide. Teratogen Carcinogen Mutagen 14:39-51.
    • (1994) Teratogen Carcinogen Mutagen , vol.14 , pp. 39-51
    • Mailhes, J.B.1    Marchetti, F.2    Phillips Jr., G.L.3    Barnhill, D.R.4
  • 28
    • 0026703325 scopus 로고
    • Creative blocks: Cell-cycle checkpoints and feedback controls
    • Murray WA (1992): Creative blocks: Cell-cycle checkpoints and feedback controls. Nature 359:599-604.
    • (1992) Nature , vol.359 , pp. 599-604
    • Murray, W.A.1
  • 29
    • 0029146196 scopus 로고
    • Kinetochore chemistry is sensitive to tension and may link mitotic forces to a cell cycle checkpoint
    • Nicklas RB, Ward SC, Gorbsky GJ (1995): Kinetochore chemistry is sensitive to tension and may link mitotic forces to a cell cycle checkpoint. J Cell Biol 130:929-939.
    • (1995) J Cell Biol , vol.130 , pp. 929-939
    • Nicklas, R.B.1    Ward, S.C.2    Gorbsky, G.J.3
  • 30
    • 0141883321 scopus 로고
    • Duration of spermatogenesis in the mouse and timing of stages of the cycle of the seminiferous epithelium
    • Oakberg EF (1956): Duration of spermatogenesis in the mouse and timing of stages of the cycle of the seminiferous epithelium. Am J Anat 99:507-516.
    • (1956) Am J Anat , vol.99 , pp. 507-516
    • Oakberg, E.F.1
  • 31
    • 0000239319 scopus 로고
    • Transillumination phase contrast microscopic techniques for evaluation of male germ cell toxicity and mutagenicity
    • Parvinen M, Toppari J, Lähdetie J (1993): Transillumination phase contrast microscopic techniques for evaluation of male germ cell toxicity and mutagenicity. Methods Toxicol 3:142-165.
    • (1993) Methods Toxicol , vol.3 , pp. 142-165
    • Parvinen, M.1    Toppari, J.2    Lähdetie, J.3
  • 34
    • 0027065109 scopus 로고
    • Mode of action of topoisomerase II-targeting agents at a specific DNA sequence. Uncoupling the DNA binding, cleavage and religation events
    • Sørensen BS, Sindling J, Andersen AH, Alsner J, Jensen PB, Westergaard O (1992): Mode of action of topoisomerase II-targeting agents at a specific DNA sequence. Uncoupling the DNA binding, cleavage and religation events. J Mol Biol 228:778-786.
    • (1992) J Mol Biol , vol.228 , pp. 778-786
    • Sørensen, B.S.1    Sindling, J.2    Andersen, A.H.3    Alsner, J.4    Jensen, P.B.5    Westergaard, O.6
  • 35
    • 0024532762 scopus 로고
    • Topoisomerase II-dependent and -independent mechanisms of etoposide resistance in Chinese hamster cell lines
    • Spiridonidis CA, Chatterjee S, Petzold SJ, Berger NA (1989): Topoisomerase II-dependent and -independent mechanisms of etoposide resistance in Chinese hamster cell lines. Cancer Res 49:644-650.
    • (1989) Cancer Res , vol.49 , pp. 644-650
    • Spiridonidis, C.A.1    Chatterjee, S.2    Petzold, S.J.3    Berger, N.A.4
  • 36
    • 0028813528 scopus 로고
    • Evidence for a second cell cycle block at G2/M by p53
    • Stewart N, Hicks GG, Paraskevas F, Mowat M (1995): Evidence for a second cell cycle block at G2/M by p53. Oncogene 10:109-115.
    • (1995) Oncogene , vol.10 , pp. 109-115
    • Stewart, N.1    Hicks, G.G.2    Paraskevas, F.3    Mowat, M.4
  • 37
    • 0015423706 scopus 로고
    • A simple technique for demonstrating centromeric heterochromatin
    • Sumner AT (1972): A simple technique for demonstrating centromeric heterochromatin. Exp Cell Res 75:304-306.
    • (1972) Exp Cell Res , vol.75 , pp. 304-306
    • Sumner, A.T.1
  • 38
    • 0028917542 scopus 로고
    • Inhibitors of topoisomerase II delay progression through mitosis and induce a doubling of the DNA content in CHO cells
    • Sumner AT (1995): Inhibitors of topoisomerase II delay progression through mitosis and induce a doubling of the DNA content in CHO cells. Exp Cell Res 217:440-447.
    • (1995) Exp Cell Res , vol.217 , pp. 440-447
    • Sumner, A.T.1
  • 39
    • 0026513079 scopus 로고
    • Discrimination of aneuploidogens from clastogens by C-banding, DNA and area measurements of micronuclei from mouse bone marrow
    • Van Hummelen P, Deleener A, Vanparys Ph, Kirsch-Volders M (1992): Discrimination of aneuploidogens from clastogens by C-banding, DNA and area measurements of micronuclei from mouse bone marrow. Mutat Res 271:13-28.
    • (1992) Mutat Res , vol.271 , pp. 13-28
    • Van Hummelen, P.1    Deleener, A.2    Vanparys, Ph.3    Kirsch-Volders, M.4
  • 40
    • 0026147704 scopus 로고
    • Proliferation- and cell cycle-dependent differences in expression of the 170 kilodalton and 180 kilodalton forms of topoisomerase II in NIH-3T3 cells
    • Woessner RD, Mattern MR, Mirabelli CK, Johnson RK, Drake FH (1991): Proliferation- and cell cycle-dependent differences in expression of the 170 kilodalton and 180 kilodalton forms of topoisomerase II in NIH-3T3 cells. Cell Growth Differ 2:209-214.
    • (1991) Cell Growth Differ , vol.2 , pp. 209-214
    • Woessner, R.D.1    Mattern, M.R.2    Mirabelli, C.K.3    Johnson, R.K.4    Drake, F.H.5
  • 41
    • 0028371761 scopus 로고
    • How meiotic cells deal with nonexchange chromosomes
    • Wolf KW (1994): How meiotic cells deal with nonexchange chromosomes. Bioessays 2:107-114.
    • (1994) Bioessays , vol.2 , pp. 107-114
    • Wolf, K.W.1
  • 42
    • 0018894285 scopus 로고
    • A comparison of diameters of micronuclei induced by clastogens and by spindle poisons
    • Yamamoto KI, Kikuchi Y (1980): A comparison of diameters of micronuclei induced by clastogens and by spindle poisons. Mutat Res 71:127-131.
    • (1980) Mutat Res , vol.71 , pp. 127-131
    • Yamamoto, K.I.1    Kikuchi, Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.