The VPS4 gene is involved in protein transport out of a yeast pre-vacuolar endosome-like compartment

Current Genetics

Volumn 31, Issue 6, 1997, Pages 469-480

  Finken Eigen, Marion ^a   Röhricht, Ralf A ^a   Köhrer, Karl ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

AAA protein family; Saccharomyces cerevisiae; VPS4 gene

Indexed keywords

ADENOSINE TRIPHOSPHATASE; BETA FRUCTOFURANOSIDASE; CARBOXYPEPTIDASE; ENZYME PRECURSOR; FUNGAL DNA; HYBRID PROTEIN; LUCIFER YELLOW; MATING HORMONE ALPHA FACTOR; SECRETORY PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; CELL VACUOLE; CONTROLLED STUDY; ENDOCYTOSIS; ENDOSOME; ENZYME RELEASE; FUNGAL GENETICS; FUNGUS MUTANT; GENE DISRUPTION; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY;

ADENOSINE TRIPHOSPHATASES; AMINO ACID SEQUENCE; BETA-FRUCTOFURANOSIDASE; BIOLOGICAL TRANSPORT; CARBOXYPEPTIDASE C; CARBOXYPEPTIDASES; CELL COMPARTMENTATION; ENDOCYTOSIS; ENDOSOMES; FUNGAL PROTEINS; GENES, DOMINANT; GENETIC COMPLEMENTATION TEST; GLYCOSIDE HYDROLASES; GOLGI APPARATUS; HYDROLASES; MOLECULAR SEQUENCE DATA; MUTATION; OPEN READING FRAMES; POINT MUTATION; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; VACUOLES;

FUNGI; SACCHAROMYCES CEREVISIAE;

EID: 1842299354     PISSN: 01728083     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002940050232     Document Type: Article

References (84)

1. Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ (1990) Basic local alignment search tool. J Mol Biol 215:403-410
2. Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K (1990) Current protocols in molecular biology. John Wiley and Sons, Green Publishing Associates and Wiley-Interscience, New York
3. Bairoch A, Bucher P, Hofmann K (1995) The PROSITE database, its status in 1995. Nucleic Acids Res 24:189-196
4. Bankaitis VA, Johnson LM, Emr SD (1986) Isolation of yeast mutants defective in protein targeting to the vacuole. Proc Natl Acad Sci USA 83:9075-9079
5. Banta LM, Robinson JS, Klionsky DJ, Emr SD (1988) Organelle assembly in yeast: characterization of yeast mutants defective in vacuolar biogenesis and protein-sorting. J Cell Biol 107: 1369-1383
6. Becker DM, Guarente L (1991) High-efficiency transformation of yeast by electroporation. Methods Enzymol 194:182-187
7. Berben G, Dumont J, Gilliquet V, Bolle P-A, Hilger F (1991) The YDp plasmids: a uniform set of vectors bearing versatile gene-disruption cassettes for Saccharomyces cerevisiae. Yeast 7: 475-477
8. Bryant NJ, Boyd A (1993) Immunoisolation of Kex2p-containing organelles from yeast demonstrates co-localisation of three processing proteinases to a single Golgi compartment. J Cell Sci 106:815-822
9. Carlson M, Botstein D (1982) Two differentially regulated mRNAs with different 5′ ends encode secreted and intracellular forms of yeast invertase. Cell 28:145-154
10. Cereghino JL, Marcusson EG, Emr SD (1995) The cytoplasmic tail domain of the vacuolar protein-sorting receptor Vps10p and a subset of VPS gene products regulate receptor stability, function, and localization. Mol Biol Cell 6:1089-1102
11. Confalonieri F, Duguet M (1995) A 200-amino-acid ATPase module in search of a basic function. BioAssays 17:639-650
12. Cooper AA, Stevens TH (1996) Vps10p cycles between the late-Golgi and pre-vacuolar compartment in its function as the sorting receptor for multiple yeast vacuolar hydrolases. J Cell Biol 133:529-541
13. Davis NG, Horecka JL, Sprague GFJ (1993) Cis-and trans-acting functions required for endocytosis of the yeast pheromone receptors. J Cell Biol 122:53-65
14. Devereux J, Haeberli P, Smithies O (1984) A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res 12:387-395
15. Distel B, Erdmann R, Gould S, Blobel G, Crane D, Cregg JM, Veenhuis M (1996) A unified nomenclature for peroxysome biogenesis factors. J Cell Biol 135:1-3
16. Dulic V, Egerton M, Elguindi I, Raths S, Singer B, Riezman H (1991) Yeast endocytosis assays. Methods Enzymol 194:697-710
17. Eakle KA, Bernstein M, Emr SD (1988) Characterization of a component of the yeast secretion machinery: identification of the SEC18 gene product. Mol Cell Biol 8:4098-4109
18. Figura von K, Hasilik A (1986) Lysosomal enzymes and their receptors. Annu Rev Biochem 55:167-193
19. Fuchs R (1991) MacPattern: protein pattern searching on the Apple Macintosh. Comput Applic Biosci 7:105-106
20. Fuller RS, Sterne RE, Thorner J (1988) Enzymes required for yeast prohormone processing. Annu Rev Physiol 50:345-362
21. Gish W, States DJ (1993) Identification of protein-coding regions by database similarity search. Nature Genetics 3:266-272
22. Graham TR, Emr SD (1991) Compartmental organization of Golgi-specific protein modification and vacuolar protein-sorting events defined in a yeast sec18 (NSF) mutant. J Cell Biol 114: 207-218
23. Graham TR, Scott PA, Emr SD (1993) Brefeldin A blocks early but not late protein-transport steps in the yeast secretory pathway. EMBO J 12:869-877
24. Haas A, Wickner W (1996) Homotypic vacuole fusion requires Sec17p (yeast a-SNAP) and Sec18p (yeast NSF). EMBO J 15: 3296-3305
25. HardingTM, Morano KA, Sidney VS, Klionsky DJ (1995) Isolation and characterization of yeast mutants in the cytoplasm-to-vacuole protein-targeting pathway. J Cell Biol 131:591-602
26. Henikoff S, Henikoff JG (1994) Protein-family classification based on searching a database of blocks. Genomics 19:97-107
27. Herman PK, Emr SD (1990) Characterization of VPS34, a gene required for vacuolar protein-sorting and vacuole segregation in Saccharomyces cerevisiae. Mol Cell Biol 10:6742-6754
28. Hoffmann CS, Winston F (1987) A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli. Gene 57:267-272
29. Horazdovsky BF, Busch GR, Emr SD (1994) VPS21 encodes a Rab5-like GTP-binding protein that is required for the sorting of yeast vacuolar proteins. EMBO J 13:1297-1309
30. Johnson LM, Bankaitis VA, Emr SD (1987) Distinct sequence determinants direct intracellular sorting and modification of a yeast vacuolar protease. Cell 48:875-885
31. Jones EW (1977) Proteinase mutants of Saccharomyces cerevisiae. Genetics 85:23-33
32. Kaiser C, Schekman R (1990) Distinct sets of SEC genes govern transport vesicle formation and fusion early in the secretory pathway. Cell 61:723-733
33. Klionsky DJ, Emr SD (1990) A new class of lysosomal/vacuolar protein-sorting signals. J Biol Chem 265:5349-5352
34. Klionsky DJ, Banta LM, Emr SD (1988) Intracellular sorting and processing of a yeast vacuolar hydrolase: proteinase A propeptide contains vacuolar targeting information. Mol Cell Biol 8:2105-2116
35. Klionsky DJ, Cueva R, Yaver DS (1992) Amino-peptidase I of Saccharomyces cerevisiae is localized to the vacuole independent of the secretory pathway. J Cell Biol 119:287-299
36. Kornfeld S, Mellman I (1989) The biogenesis of lysosomes. Annu Rev Cell Biol 5:483-525
37. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685
38. Latterich M, Fröhlich KU, Schekman R (1995) Membrane fusion and the cell cycle: cdc48p participates in the fusion of ER membranes. Cell 82:885-893
39. Logan KM, Knight KL (1993) Mutagenesis of the P-loop motif in the ATP binding site of the RecA protein from Escherichia coli. J Mol Biol 232:1048-1059
40. Marcusson EG, Horazdovsky BF, Cereghino JL, Gharakhanian E, Emr SD (1994) The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene. Cell 77: 579-586
41. Mayer A, Wickner W, Haas A (1996) Sec18p (NSF)-driven release of sec17p (a-SNAP) can precede docking and fusion of yeast vacuoles. Cell 85:83-94
42. Miller J (1972) Experiments in molecular genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
43. +-ATPase-defective yeast: identification of six new END genes. J Cell Biol 127:373-386
44. Nakai M, Endo T, Hase T, Matsubara H (1993) Intramitochondrial protein-sorting: isolation and characterization of the yeast MSP1 gene which belongs to a novel family of putative ATPases. J Biol Chem 268:24262-24269
45. Nothwehr SF, Bryant NJ, Stevens TH (1996) The newly identified yeast GRD genes are required for retention of late-Golgi membrane proteins. Mol Cell Biol 16:2700-2707
46. Orr-Weaver TL, Szostak JW, Rothstein RJ (1983) Genetic applications of yeast transformation with linear and gapped plasmids. Methods Enzymol 101:228-245
47. Paravicini G, Horazdovsky BF, Emr SD (1992) Alternative pathways for the sorting of soluble vacuolar proteins in yeast: a vps35 null-mutant missorts and secretes only a subset of vacuolar hydrolases. Mol Biol Cell 3:415-427
48. Périer F, Coulter KL, Liang H, Radeke CM, Gaber RF, Vandenberg CA (1994) Identification of a novel mammalian member of the NSF/CDC48p/Pas1p/TBP-1 family through heterologous expression in yeast. FEES Lett 351:286-290
49. Philippsen P, Stotz A, Scherf C (1991) DNA of Saccharomyces cerevisiae. Methods Enzymol 194:169-181
50. Piper RC, Cooper A, Yang H, Stevens TH (1995) VPS27 controls vacuolar and endocytic traffic through a pre-vacuolar compartment in Saccharomyces cerevisiae. J Cell Biol 131:603-617
51. Preston RA, Murphy RF, Jones EW (1989) Assay of vacuolar pH in yeast and identification of acidification-defective mutants. Proc Natl Acad Sci USA 86:7027-7031
52. Raymond CK, Howald-Stevenson I, Vater CA, Stevens TH (1992) Morphological classification of the yeast vacuolar protein-sorting mutants: evidence for a pre-vacuolar compartment in class E vps mutants. Mol Biol Cell 3:1389-1402
53. Rexach MF, Schekman RW (1991) Distinct biochemical requirements for the budding, targeting, and fusion of ER-derived transport vesicles. J Cell Biol 114:219-229
54. Rieder S, Banta L, Köhrer K, McCaffery JM, Emr SD (1996) A multilamellar endosome-like compartment accumulates in the yeast vps28 vacuolar protein-sorting mutant. Mol Biol Cell 7:985-999
55. Riezman H (1985) Endocytosis in yeast: several of the yeast secretory mutants are defective in endocytosis. Cell 40:1001-1009
56. Roberts CJ, Raymond CK, Yamashiro CT, Stevens TH (1991) Methods for studying the yeast vacuole. Methods Enzymol 194: 644-661
57. Robinson JS, Klionsky DJ, Banta LM, Emr SD (1988) Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in delivery and processing of multiple vacuolar hydrolases. Mol Cell Biol 8:4936-4948
58. Rothman JE (1994) Mechanisms of intracellular protein transport. Nature 372:55-63
59. Rothman JH, Stevens TH (1986) Protein sorting in yeast: mutants defective in vacuole biogenesis mislocalize vacuolar proteins into the late secretory pathway. Cell 47:1041-1051
60. Rothman JH, Howald I, Stevens TH (1989a) Characterization of genes required for protein-sorting and vacuolar function in the yeast Saccharomyces cerevisiae. EMBO J 8:2057-2065
61. Rothman JH, Yamashiro CT, Kane PM, Stevens TH (1989b) Protein targeting to the yeast vacuole. Trends Biochem Sci 14:347-350
62. Rothstein RJ (1983) One-step gene disruption in yeast. Methods Enzymol 101:202-211
63. Saraste M, Sibbald PR, Wittinghofer A (1990) The P-loop - a common motif in ATP-and GTP-binding proteins. Trends Biochem Sci 15:430-434
64. Schwaiger H, Hasilik A, von Figura K, Wiemken A, Tanner W (1982) Carbohydrate-free carboxypeptidase Y is transferred into the lysosome-like yeast vacuole. Biochem Biophys Res Commun 104:950-956
65. Sengstag C (1993) The sequence of Saccharomyces cerevisiae cloning vector pCS19 allowing direct selection for DNA inserts. Gene 124:141-142
66. Sherman F (1991) Getting started with yeast. Methods Enzymol 194:3-21
67. Sherman F, Fink GR, Hicks JB (1986) Methods in yeast genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
68. Sikorski RS, Hieter P (1989) A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122:19-27
69. Söllner T, Whiteheart SW, Brunner M, Erdjument-Bromage H, Geromonos S, Tempst P, Rothman JE (1993) SNAP receptors implicated in vesicle targeting and fusion. Nature 362:318-324
70. Stevens T, Esmon B, Schekman R (1982) Early stages in the yeast secretory pathway are required for transport of carboxypeptidase Y to the vacuole. Cell 30:439-448
71. Tanner W, Lehle L (1987) Protein glycosylation in yeast. Biochim Biophys Acta 906:81-99
72. Thompson JD, Higgins DG, Gibson TJ (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties, and weight matrix choice. Nucleic Acids Res 22:4673-4680
73. Valls LA, Hunter CP, Rothman JH, Stevens TH (1987) Protein sorting in yeast: the localization determinant of yeast vacuolar carboxypeptidase Y resides in the propeptide. Cell 48:887-897
74. Valls LA, Winther JR, Stevens TH (1990) Yeast carboxypeptidase Y vacuolar targeting signal is defined by four pro-peptide amino acids. J Cell Biol 111:361-368
75. Vida TA, Emr SD (1995) A new vital stain for visualizing vacuolar membrane dynamics and endocytosis in yeast. J Cell Biol 128:779-792
76. Vida TA, Huyer G, Emr SD (1993) Yeast vacuolar pro-enzymes are sorted in the late Golgi complex and transported to the vacuole via a pre-vacuolar endosome-like compartment. J Cell Biol 121: 1245-1256
77. Voorn-Brouwer T, van der Leij I, Hemrika W, Distel B, Tabak HF (1993) Sequence of the PAS8 gene, the product of which is essential for biogenesis of peroxysomes in Saccharomyces cerevisiae. Biochim Biophys Acta 1216:325-328
78. Walker JE, Saraste M, Runswick MJ, Gay NJ (1982) Distantly related sequences in the α-and β-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO J 1:945-951
79. Westphal V, Marcusson EG, Winther JR, Emr SD, van den Hazel HB (1996) Multiple pathways for vacuolar sorting of yeast proteinase A. J Biol Chem 271:11865-11870
80. Whiteheart SW, Rossnagel K, Buhrow SA, Brunner M, Jaenicke R, Rothman JE (1994) N-ethylmaleimide-sensitive fusion protein: a trimeric ATPase whose hydrolysis of ATP is required for membrane fusion. J Cell Biol 126:945-954
81. Wickerham LJ (1949) A critical evaluation of the nitrogen assimilation tests commonly used in the classification of yeasts. J Bacteriol 52:293-301
82. Wilsbach K, Payne GS (1993) Dynamic retention of TGN membrane proteins in Saccharomyces cerevisiae. Trends Cell Biol 3: 426-432
83. Winther JR, Stevens TH, Kielland-Brandt MC (1991) Yeast carboxypeptidase Y requires glycosylation for efficient intracellular transport, but not for vacuolar sorting, in vivo stability, or activity. Eur J Biochem 197:681-689
84. Yoshihisa T, Anraku Y (1990) A novel pathway of import of α-mannosidase, a marker enzyme of the vacuolar membrane, in Saccharomyces cerevisiae. J Biol Chem 265:22418-22425