Elevated plasma endothelin-1 levels and vascular dysregulation in patients with rheumatoid arthritis

Medical Science Monitor

Volumn 8, Issue 9, 2002, Pages

  Pache, Mona ^a   Schwarz, Hans A ^a   Kaiser, Hedwig J ^a   Wüest, Peter ^a   Klöti, Manuel ^a   Dubler, Barbara ^a   Flammer, Josef ^a  

^a UNIVERSITY EYE CLINIC   (Switzerland)

Author keywords

Endothelin 1; Nailfold capillaroscopy; Rheumatoid arthritis; Vascular dysregulation

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; ENDOTHELIN 1; ENDOTHELIN RECEPTOR ANTAGONIST;

ADULT; AGED; ARTICLE; CAPILLAROSCOPY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; MALE; PROTEIN BLOOD LEVEL; PROVOCATION TEST; RADIOIMMUNOASSAY; RHEUMATOID ARTHRITIS; VASCULAR DISEASE; VASOSPASM;

ADULT; AGED; ARTHRITIS, RHEUMATOID; CASE-CONTROL STUDIES; ENDOTHELIN-1; FEMALE; HUMANS; MALE; MICROSCOPIC ANGIOSCOPY; MIDDLE AGED; RADIOIMMUNOASSAY; REGIONAL BLOOD FLOW; TIME FACTORS;

EID: 18344419434     PISSN: 12341010     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Rothschild BM, Masi AT: Pathogenesis of rheumatoid arthritis: a vascular hypothesis. Semin Arthritis Rheum, 1982; 12(1): 11-31
2. Flammer J, Pache M, Resink T: Vasospasm, its role in the pathogenesis of diseases with particular reference to the eye. Prog Retin Eye Res, 2001; 20(3): 319-349
3. Haq A, El-Ramahi K, Al-Dalaan A, Al-Sedairy ST: Serum and synovial fluid concentrations of endothelin-1 in patients with rheumatoid arthritis. J Med, 1999; 30(1-2): 51-60
4. Yoshida H, Imafuku Y, Ohhara M et al: Endothelin-1 production by human synoviocytes. Ann Clin Biochem, 1998; 35(Pt 2): 290-4
5. Schrader J, Tebbe U, Borries M et al.: [Plasma endothelin in normal probands and patients with nephrologic-rheumatologic and cardiovascular diseases]. Klin Wochenschr, 1990; 68(15): 774-9
6. van der Heijde DM, van't Hof MA, van Riel PL et al: Judging disease activity in clinical practice in rheumatoid arthritis: first step in the development of a disease activity score. Ann Rheum Dis, 1990; 49(11): 916-20
7. Moreau P, Takase H, Kung CF et al: Blood pressure and viscular effects of endothelin blockade in chronic nitric oxide-deficient hypertension. Hypertension, 1997; 29(3): 763-9
8. Gasser P, Flammer J: Blood-cell velocity in the nailfold capillaries of patients with normal-tension and high-tension glaucoma. Am J Ophthalmol, 1991; 111(5): 585-8
9. Simonson MS, Dunn MJ: Cellular signaling by peptides of endothelin gene family. FASEB J, 1990; 4(2989)
10. Lerman A, Edwards BS, Hallett JW et al: Circulating and tissue endothelin immunoreactivity in advanced atherosclerosis. N Engl J Med, 1991; 325(14): 997-1001
11. Nakayama K, Ishigai Y, Uchida H, Tanaka Y: Potentiation by endothelin-1 of 5-hydroxytryptamine-induced contraction in coronary artery of the pig. Br J Pharmacol, 1991; 104(4): 978-86
12. Ishiguro N, Ito T, Miyazaki K, Iwata H: Matrix metalloproteinases, tissue inhibitors of metalloproteinases, and glycosaminoglycans in synovial fluid from patients with rheumatoid arthritis. J Rheumatol, 1999; 26(1): 34-40
13. Fernandez-Patron C, Radomski MW, Davidge ST: Vascular matrix metalloproteinase-2 cleaves big endothelin-I yielding a novel vasoconstrictor. Circ Res, 1999; 85(10): 906-11
14. Meyer P, Lang MG, Flammer J, Luscher TF: Effects of calcium channel blockers on the response to endothelin-1, bradykinin and sodium nitroprusside in porcine ciliary arteries. Exp Eye Res, 1995; 60(5): 505-10
15. 2+ channel blocker, on the normal and endothelin-1-disturbed circulation in the optic nerve head of rabbits. J Ocul Pharmacol Ther, 2001; 17(2): 131-49