-
1
-
-
0028116504
-
Inhibition of HIV-1 protease by an orally-bioavailable inhibitor containing an imidazole-derived peptide bond replacement: Crystallographic and pharmacokinetic analysis
-
Abdel-Meguid, S.S., Metcalf, B.W., Carr, T.J., DeMarsh, P.J., DesJarlais, R.I., Fisher, S., Green, D.A., Ivanoff, L., Lambert, D.M., Murthy, K.H., Petteway, S.R., Jr., Tomaszek, T.A., Winbone, E., Zhao, B., Dreyer, G.B. and Meek, T.D. (1994) Inhibition of HIV-1 protease by an orally-bioavailable inhibitor containing an imidazole-derived peptide bond replacement: Crystallographic and pharmacokinetic analysis. Biochemistry 33, 11671-11677.
-
(1994)
Biochemistry
, vol.33
, pp. 11671-11677
-
-
Abdel-Meguid, S.S.1
Metcalf, B.W.2
Carr, T.J.3
DeMarsh, P.J.4
DesJarlais, R.I.5
Fisher, S.6
Green, D.A.7
Ivanoff, L.8
Lambert, D.M.9
Murthy, K.H.10
Petteway S.R., Jr.11
Tomaszek, T.A.12
Winbone, E.13
Zhao, B.14
Dreyer, G.B.15
Meek, T.D.16
-
2
-
-
0343949656
-
Sulphated sugar alpha-cyclodextrin sulphate, a uniquely potent anti-HIV agent, also exhibits marked synergism with AZT, and lymphoproliferative activity
-
Anand, R., Nayyar, S., Pitha, J. and Merril, C.R. (1990) Sulphated sugar alpha-cyclodextrin sulphate, a uniquely potent anti-HIV agent, also exhibits marked synergism with AZT, and lymphoproliferative activity. Antiviral Chem. Chemother. 1, 41-46.
-
(1990)
Antiviral Chem. Chemother.
, vol.1
, pp. 41-46
-
-
Anand, R.1
Nayyar, S.2
Pitha, J.3
Merril, C.R.4
-
3
-
-
0022373653
-
Induction of the early stages of friend erythroleukemia with helper-free friend spleen focus-forming virus
-
Berger, S.A., Sanderson, N., Bernstein, A. and Handkins, W.D. (1985) Induction of the early stages of Friend erythroleukemia with helper-free Friend spleen focus-forming virus. Proc. Natl. Acad. Sci. USA 82, 6913-6917.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 6913-6917
-
-
Berger, S.A.1
Sanderson, N.2
Bernstein, A.3
Handkins, W.D.4
-
4
-
-
0022370204
-
Roles of helper and defective retroviral genomes in murine erythroleukemia: Studies of spleen focus-forming virus in the absence of helper
-
Bestwick, R.K., Handkins, W.D. and Kabat, D. (1985) Roles of helper and defective retroviral genomes in murine erythroleukemia: Studies of spleen focus-forming virus in the absence of helper. J. Virol. 56, 660-664.
-
(1985)
J. Virol.
, vol.56
, pp. 660-664
-
-
Bestwick, R.K.1
Handkins, W.D.2
Kabat, D.3
-
5
-
-
0025552016
-
Therapeutic activity of reverse transcriptase inhibitors in murine retrovirus models
-
Black, P.L., Ussery, M.A., Rankin, J.T., Jr. and Chirigos, M.A. (1990) Therapeutic activity of reverse transcriptase inhibitors in murine retrovirus models. Ann. NY Acad. Sci. 616, 486-489.
-
(1990)
Ann. NY Acad. Sci.
, vol.616
, pp. 486-489
-
-
Black, P.L.1
Ussery, M.A.2
Rankin J.T., Jr.3
Chirigos, M.A.4
-
6
-
-
0027458948
-
Antiretroviral activities of protease inhibitors against murine leukemia virus and simian immunodeficiency virus in tissue culture
-
Black, P.L., Downs, M.B., Lewis, M.G., Ussery, M.A., Dreyer, G.B., Petteway, S.R., Jr. and Lambert, D.M. (1993) Antiretroviral activities of protease inhibitors against murine leukemia virus and simian immunodeficiency virus in tissue culture. Antimicrob. Agents Chemother. 37, 71-77.
-
(1993)
Antimicrob. Agents Chemother.
, vol.37
, pp. 71-77
-
-
Black, P.L.1
Downs, M.B.2
Lewis, M.G.3
Ussery, M.A.4
Dreyer, G.B.5
Petteway S.R., Jr.6
Lambert, D.M.7
-
7
-
-
78651144186
-
Studies with the murine leukemogenic rauscher virus. III. An in vivo assay for anti-viral agents
-
Chirigos, M.A. (1964) Studies with the murine leukemogenic Rauscher virus. III. An in vivo assay for anti-viral agents. Cancer Res. 24, 1035-1041.
-
(1964)
Cancer Res.
, vol.24
, pp. 1035-1041
-
-
Chirigos, M.A.1
-
8
-
-
0025296098
-
Antiviral efficacy of imexon in the rauscher murine retrovirus AIDS model
-
Chirigos, M.A., Ussery, M.A., Rankin, J.T., Jr., Herrmann, D., Bicker, U. and Black, P.L. (1990) Antiviral efficacy of imexon in the Rauscher murine retrovirus AIDS model. Immunopharm. Immunotox. 12, 1-21.
-
(1990)
Immunopharm. Immunotox.
, vol.12
, pp. 1-21
-
-
Chirigos, M.A.1
Ussery, M.A.2
Rankin J.T., Jr.3
Herrmann, D.4
Bicker, U.5
Black, P.L.6
-
9
-
-
0023213331
-
Sequences responsible for the altered erythropoietin responsiveness in spleen focus-forming virus strain SFFVp-infected cells are localized to a 678-base-pair region at the 3′ end of the envelope gene
-
Chung, S., Wolff, L. and Ruscetti, S. (1987) Sequences responsible for the altered erythropoietin responsiveness in spleen focus-forming virus strain SFFVp-infected cells are localized to a 678-base-pair region at the 3′ end of the envelope gene. J. Virol. 61, 1661-1664.
-
(1987)
J. Virol.
, vol.61
, pp. 1661-1664
-
-
Chung, S.1
Wolff, L.2
Ruscetti, S.3
-
10
-
-
0001957324
-
Genome structure
-
R. Weiss, N. Teich, H. Varmus and J. Coffin (Eds.), Cold Spring Harbor Laboratory, New York
-
Coffin, J.M. (1985) Genome structure. In: R. Weiss, N. Teich, H. Varmus and J. Coffin (Eds.), RNA Tumor Viruses, 2nd edn. Cold Spring Harbor Laboratory, New York, pp. 17-74.
-
(1985)
RNA Tumor Viruses, 2nd Edn.
, pp. 17-74
-
-
Coffin, J.M.1
-
11
-
-
0021931766
-
A deletion mutation in the 5′ part of the pol gene of Moloney murine leukemia virus blocks proteolytic processing of the gag and pol polyproteins
-
Crawford, S. and Goff, S.P. (1985) A deletion mutation in the 5′ part of the pol gene of Moloney murine leukemia virus blocks proteolytic processing of the gag and pol polyproteins. J. Virol. 53, 899-907.
-
(1985)
J. Virol.
, vol.53
, pp. 899-907
-
-
Crawford, S.1
Goff, S.P.2
-
12
-
-
0024792446
-
Inhibition of human immunodeficiency virus 1 protease in vitro: Rational design of substrate analogue inhibitors
-
Dreyer, G.B., Metcalf, B.W., Tomaszek, T.A., Jr., Carr, T.J., Chandler, A.C., III, Hyland, L., Moore, M.L., Strickler, J.E., Debouck, C. and Meek, T.D. (1989) Inhibition of human immunodeficiency virus 1 protease in vitro: Rational design of substrate analogue inhibitors. Proc. Natl. Acad. Sci. USA 86, 9752-9756.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 9752-9756
-
-
Dreyer, G.B.1
Metcalf, B.W.2
Tomaszek T.A., Jr.3
Carr, T.J.4
Chandler A.C. III5
Hyland, L.6
Moore, M.L.7
Strickler, J.E.8
Debouck, C.9
Meek, T.D.10
-
13
-
-
0026663760
-
Hydroxyethylene isostere inhibitors of human immunodeficiency virus-1 protease: Structure-activity analysis using enzyme kinetics. X-ray crystallography, and infected T-cell assays
-
Dreyer, G.B., Lambert, D.M., Meek, T.D., Carr, T.J., Tomaszek, T.A., Jr., Fernandez, A.V., Bartus, H., Cacciavillani, E., Hassel, A.M., Minnich, M., Petteway, S.R., Jr., Metcalf, B.W. and Lewis, M. (1992) Hydroxyethylene isostere inhibitors of human immunodeficiency virus-1 protease: Structure-activity analysis using enzyme kinetics. X-ray crystallography, and infected T-cell assays. Biochemistry 31, 6646-6659.
-
(1992)
Biochemistry
, vol.31
, pp. 6646-6659
-
-
Dreyer, G.B.1
Lambert, D.M.2
Meek, T.D.3
Carr, T.J.4
Tomaszek T.A., Jr.5
Fernandez, A.V.6
Bartus, H.7
Cacciavillani, E.8
Hassel, A.M.9
Minnich, M.10
Petteway S.R., Jr.11
Metcalf, B.W.12
Lewis, M.13
-
14
-
-
0024843742
-
Animal models of AIDS
-
Gardner, M.B. and Luciw, P.A. (1989) Animal models of AIDS. FASEB J. 3, 2593-2606.
-
(1989)
FASEB J.
, vol.3
, pp. 2593-2606
-
-
Gardner, M.B.1
Luciw, P.A.2
-
15
-
-
0019507492
-
Isolation and properties of Moloney murine leukemia virus mutants: Use of a rapid assay for release of virion reverse transcriptase
-
Goff, S., Traktman, P. and Baltimore, D. (1981) Isolation and properties of Moloney murine leukemia virus mutants: Use of a rapid assay for release of virion reverse transcriptase. J. Virol. 38, 239-248.
-
(1981)
J. Virol.
, vol.38
, pp. 239-248
-
-
Goff, S.1
Traktman, P.2
Baltimore, D.3
-
16
-
-
0342394457
-
Role of capsid precursor processing and myristoylation in morphogenesis and infectivity of human immunodeficiency virus type 1
-
Gottlinger, H.G., Sodroski, J.G. and Haseltine, W.A. (1989) Role of capsid precursor processing and myristoylation in morphogenesis and infectivity of human immunodeficiency virus type 1. Proc. Natl. Acad. Sci. USA 86, 5781-5785.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 5781-5785
-
-
Gottlinger, H.G.1
Sodroski, J.G.2
Haseltine, W.A.3
-
17
-
-
0025773798
-
Novel antifungal drug delivery: Stable Amphotericin B-cholesteryl sulfate discs
-
Guo, L.S.S., Fielding, R.M., Lasic, D.D., Hamilton, R.L. and Mufson, D. (1991) Novel antifungal drug delivery: Stable Amphotericin B-cholesteryl sulfate discs. Int. J. Pharm. 75, 45-54.
-
(1991)
Int. J. Pharm.
, vol.75
, pp. 45-54
-
-
Guo, L.S.S.1
Fielding, R.M.2
Lasic, D.D.3
Hamilton, R.L.4
Mufson, D.5
-
18
-
-
0026755676
-
An ELISA system for evaluating antiretroviral activity against rauscher murine leukemia virus
-
Hollingshead, M.G., Westbrook, L., Ross, M.J., Bailey, J., Quails, K.J. and Allen, L.B. (1992) An ELISA system for evaluating antiretroviral activity against Rauscher murine leukemia virus. Antiviral Res. 18, 267-274.
-
(1992)
Antiviral Res.
, vol.18
, pp. 267-274
-
-
Hollingshead, M.G.1
Westbrook, L.2
Ross, M.J.3
Bailey, J.4
Quails, K.J.5
Allen, L.B.6
-
19
-
-
0021846499
-
Murine leukemia virus maturation: Protease region required for conversion from 'immature' to 'mature' core form and for virus infectivity
-
Katoh, I., Yoshinaka, Y., Rein, A., Shibuya, M., Odaka, T. and Oroszlan, S. (1985) Murine leukemia virus maturation: Protease region required for conversion from 'immature' to 'mature' core form and for virus infectivity. Virology 145, 280-292.
-
(1985)
Virology
, vol.145
, pp. 280-292
-
-
Katoh, I.1
Yoshinaka, Y.2
Rein, A.3
Shibuya, M.4
Odaka, T.5
Oroszlan, S.6
-
20
-
-
0023199453
-
Inhibition of retroviral protease activity by an aspartyl proteinase inhibitor
-
Katoh, I., Yasunaga, T., Ikawa, Y. and Yoshinaka, Y. (1987) Inhibition of retroviral protease activity by an aspartyl proteinase inhibitor. Nature 329, 654-656.
-
(1987)
Nature
, vol.329
, pp. 654-656
-
-
Katoh, I.1
Yasunaga, T.2
Ikawa, Y.3
Yoshinaka, Y.4
-
21
-
-
0005241362
-
Active human immunodeficiency virus protease is required for viral infectivity
-
Kohl, N.E., Emini, E.A., Schleif, W.A., Davis, L.J., Heimbach, J.C., Dixon, R.A., Scolnick, E.M. and Sigal, I.S. (1988) Active human immunodeficiency virus protease is required for viral infectivity. Proc. Natl. Acad. Sci. USA 85, 4686-4690.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 4686-4690
-
-
Kohl, N.E.1
Emini, E.A.2
Schleif, W.A.3
Davis, L.J.4
Heimbach, J.C.5
Dixon, R.A.6
Scolnick, E.M.7
Sigal, I.S.8
-
22
-
-
0022546859
-
HTLV-III gag protein is processed in yeast cells by the virus pol-protease
-
Kramer, R.A., Schnaber, M.D., Skalka, A.M., Ganguly, K., Wong-Staal, F. and Reddy, E.P. (1986) HTLV-III gag protein is processed in yeast cells by the virus pol-protease. Science 231, 1580-1584.
-
(1986)
Science
, vol.231
, pp. 1580-1584
-
-
Kramer, R.A.1
Schnaber, M.D.2
Skalka, A.M.3
Ganguly, K.4
Wong-Staal, F.5
Reddy, E.P.6
-
24
-
-
85030194733
-
Statine-based inhibitors of HIV-1 protease block the production of infectious progeny virus in HIV-1 infected human T4 cells and in mouse fibroblasts infected with murine leukemia virus
-
Florence, Abstract No. WA1005
-
Lai, M.T., Hui, K., Tang, J., Dee, A., Bowdon, B., Buckheit, R., Margolin, N., Vlahos, C. and Colacino, J. (1991) Statine-based inhibitors of HIV-1 protease block the production of infectious progeny virus in HIV-1 infected human T4 cells and in mouse fibroblasts infected with murine leukemia virus. VII International Conference on AIDS, Florence, Abstract No. WA1005.
-
(1991)
VII International Conference on AIDS
-
-
Lai, M.T.1
Hui, K.2
Tang, J.3
Dee, A.4
Bowdon, B.5
Buckheit, R.6
Margolin, N.7
Vlahos, C.8
Colacino, J.9
-
25
-
-
0027497412
-
Impeded progression of Friend disease in mice by an inhibitor of retroviral proteases
-
Lai, M.T., Tang, J., Wroblewski, V., Dee, A.G., Margolin, N., Vlahos, C., Bowdon, B., Buckheit, R., Colacino, J. and Hui, K.Y. (1993) Impeded progression of Friend disease in mice by an inhibitor of retroviral proteases. JAIDS. 6, 24-31.
-
(1993)
JAIDS
, vol.6
, pp. 24-31
-
-
Lai, M.T.1
Tang, J.2
Wroblewski, V.3
Dee, A.G.4
Margolin, N.5
Vlahos, C.6
Bowdon, B.7
Buckheit, R.8
Colacino, J.9
Hui, K.Y.10
-
26
-
-
0026772902
-
Human immunodeficiency virus type 1 protease inhibitors irreversibly block infectivity of purified virions from chronically infected cells
-
Lambert, D.M., Petteway, S.R., McDanal, C.E., Hart, T.K., Leary, J.J., Dreyer, G.B., Meek, T.D., Bugelski, P.J., Bolognesi, D.P., Metcalf, B.W. and Matthews, T.J. (1992) Human immunodeficiency virus type 1 protease inhibitors irreversibly block infectivity of purified virions from chronically infected cells. Antimicrob. Agents Chemother. 36, 982-988.
-
(1992)
Antimicrob. Agents Chemother.
, vol.36
, pp. 982-988
-
-
Lambert, D.M.1
Petteway, S.R.2
McDanal, C.E.3
Hart, T.K.4
Leary, J.J.5
Dreyer, G.B.6
Meek, T.D.7
Bugelski, P.J.8
Bolognesi, D.P.9
Metcalf, B.W.10
Matthews, T.J.11
-
27
-
-
0025099016
-
A synthetic HIV-1 protease inhibitor with antiviral activity arrests HIV-like particle maturation
-
McQuade, T.J., Tomasselli, A.G., Liu, L., Karacostas, V., Moss, B., Sawyer, T.K., Heinrikson, R.L. and Tarpley, W.G. (1990) A synthetic HIV-1 protease inhibitor with antiviral activity arrests HIV-like particle maturation. Science 247, 454-456.
-
(1990)
Science
, vol.247
, pp. 454-456
-
-
McQuade, T.J.1
Tomasselli, A.G.2
Liu, L.3
Karacostas, V.4
Moss, B.5
Sawyer, T.K.6
Heinrikson, R.L.7
Tarpley, W.G.8
-
28
-
-
0000004753
-
Human immunodeficiency virus 1 protease expressed in Escherichia coli behaves as a dimeric aspartic protease
-
Meek, T.D., Dayton, B.D., Metcalf, B.W., Dreyer, G.B., Strickler, J.E., Gorniak, J.G., Rosenberg, M., Moore, M.L., Magaard, V.W. and Debouck, C. (1989) Human immunodeficiency virus 1 protease expressed in Escherichia coli behaves as a dimeric aspartic protease. Proc. Natl. Acad. Sci. USA 86, 1841-1845.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 1841-1845
-
-
Meek, T.D.1
Dayton, B.D.2
Metcalf, B.W.3
Dreyer, G.B.4
Strickler, J.E.5
Gorniak, J.G.6
Rosenberg, M.7
Moore, M.L.8
Magaard, V.W.9
Debouck, C.10
-
29
-
-
0025159205
-
Inhibition of HIV-1 protease in infected T-lymphocytes by synthetic peptide analogues
-
Meek, T.D., Lambert, D.M., Dreyer, G.B., Carr, T.J., Tomaszek, T.A., Jr., Moore, M.L., Strickler, J.E., Debouck, C., Hyland, L.J., Metcalf, B.W. and Petteway, S.R., Jr. (1990) Inhibition of HIV-1 protease in infected T-lymphocytes by synthetic peptide analogues. Nature 343, 90-92.
-
(1990)
Nature
, vol.343
, pp. 90-92
-
-
Meek, T.D.1
Lambert, D.M.2
Dreyer, G.B.3
Carr, T.J.4
Tomaszek T.A., Jr.5
Moore, M.L.6
Strickler, J.E.7
Debouck, C.8
Hyland, L.J.9
Metcalf, B.W.10
Petteway S.R., Jr.11
-
30
-
-
0024492495
-
Crystal structure of a retroviral protease proves relationship to aspartic protease family
-
Miller, M., Jaskolski, M., Rao, J.K., Leis, J. and Wlodawer, A. (1989) Crystal structure of a retroviral protease proves relationship to aspartic protease family. Nature 337, 576-579.
-
(1989)
Nature
, vol.337
, pp. 576-579
-
-
Miller, M.1
Jaskolski, M.2
Rao, J.K.3
Leis, J.4
Wlodawer, A.5
-
31
-
-
0023829221
-
Processing protease and reverse transcriptase from human immunodeficiency virus type I polyprotein in Escherichia coli
-
Mous, J., Heimer, E.P. and LeGrice, S.F. (1988) Processing protease and reverse transcriptase from human immunodeficiency virus type I polyprotein in Escherichia coli. J. Virol. 62, 1433-1436.
-
(1988)
J. Virol.
, vol.62
, pp. 1433-1436
-
-
Mous, J.1
Heimer, E.P.2
LeGrice, S.F.3
-
32
-
-
0024555898
-
Three-dimensional structure of aspartyl protease from human immune deficiency virus HIV-1
-
Navia, M.A., Fitzgerald, P.M., McKeever, B.M., Leu, C.T., Heimbach, J.C., Herber, W.K., Sigal, I.S., Darke, P.L. and Springer, J.P. (1989) Three-dimensional structure of aspartyl protease from human immune deficiency virus HIV-1. Nature 337, 615-620.
-
(1989)
Nature
, vol.337
, pp. 615-620
-
-
Navia, M.A.1
Fitzgerald, P.M.2
McKeever, B.M.3
Leu, C.T.4
Heimbach, J.C.5
Herber, W.K.6
Sigal, I.S.7
Darke, P.L.8
Springer, J.P.9
-
33
-
-
0023189868
-
A structural model for the retroviral proteases
-
Pearl, L.H. and Taylor, W.R. (1987a) A structural model for the retroviral proteases. Nature 329, 351-354.
-
(1987)
Nature
, vol.329
, pp. 351-354
-
-
Pearl, L.H.1
Taylor, W.R.2
-
34
-
-
0023646642
-
Sequence specificity of retroviral proteases
-
Pearl, L.H. and Taylor, W.R. (1987b) Sequence specificity of retroviral proteases. Nature 338, 482.
-
(1987)
Nature
, vol.338
, pp. 482
-
-
Pearl, L.H.1
Taylor, W.R.2
-
35
-
-
0024334170
-
Role of human immunodeficiency virus type 1-specific protease in core protein maturation and viral infectivity
-
Peng, C., Ho, B.K., Chang, T.W. and Chang, N.T. (1989) Role of human immunodeficiency virus type 1-specific protease in core protein maturation and viral infectivity. J. Virol. 63, 2550-2556.
-
(1989)
J. Virol.
, vol.63
, pp. 2550-2556
-
-
Peng, C.1
Ho, B.K.2
Chang, T.W.3
Chang, N.T.4
-
36
-
-
84959763074
-
A virus-induced disease of mice characterized by erythrocytopoiesis and lymphoid leukemia
-
Rauscher, F.J. (1962) A virus-induced disease of mice characterized by erythrocytopoiesis and lymphoid leukemia. J. Natl. Cancer Inst. 29, 515-543.
-
(1962)
J. Natl. Cancer Inst.
, vol.29
, pp. 515-543
-
-
Rauscher, F.J.1
-
37
-
-
0025268321
-
Rational design of peptide-based HIV proteinase inhibitors
-
Roberts, N.A., Martin, J.A., Kinchington, D., Broadhurst, A.V., Craig, J.C., Duncan, I.B., Galpin, S.A., Handa, B.K., Kay, J., Kröhn, A., Lambert, R.W., Merrett, J.H., Mills, J.S., Parkes, K.E.B., Redshaw, S., Ritchie, A.J., Taylor, D.L., Thomas, G.J. and Machin, P.J. (1990) Rational design of peptide-based HIV proteinase inhibitors. Science 248, 358-361.
-
(1990)
Science
, vol.248
, pp. 358-361
-
-
Roberts, N.A.1
Martin, J.A.2
Kinchington, D.3
Broadhurst, A.V.4
Craig, J.C.5
Duncan, I.B.6
Galpin, S.A.7
Handa, B.K.8
Kay, J.9
Kröhn, A.10
Lambert, R.W.11
Merrett, J.H.12
Mills, J.S.13
Parkes, K.E.B.14
Redshaw, S.15
Ritchie, A.J.16
Taylor, D.L.17
Thomas, G.J.18
Machin, P.J.19
-
38
-
-
0014898897
-
Plaque assay techniques for murine leukemia viruses
-
Rowe, W.P., W.E. Pugh and J.W. Hartley (1970) Plaque assay techniques for murine leukemia viruses. Virol. 42, 1136-1139.
-
(1970)
Virol.
, vol.42
, pp. 1136-1139
-
-
Rowe, W.P.1
Pugh, W.E.2
Hartley, J.W.3
-
39
-
-
0025286680
-
Interferon-alpha and 3′-azido-3′-deoxythymidine are highly synergistic in mice and prevent viremia after acute retrovirus exposure
-
Ruprecht, R.M., Chou, T.C., Chipty, F., Sosa, M.G., Mullaney, S., O'Brien, L. and Rosas, D. (1990) Interferon-alpha and 3′-azido-3′-deoxythymidine are highly synergistic in mice and prevent viremia after acute retrovirus exposure. J. Acquir. Immune Defic. Syndr. 3, 591-600.
-
(1990)
J. Acquir. Immune Defic. Syndr.
, vol.3
, pp. 591-600
-
-
Ruprecht, R.M.1
Chou, T.C.2
Chipty, F.3
Sosa, M.G.4
Mullaney, S.5
O'Brien, L.6
Rosas, D.7
-
40
-
-
0001650127
-
Human immunodeficiency virus has an aspartic-type protease that can be inhibited by pepstatin A
-
Seelmeier, S., Schmidt, H., Turk, V. and von der Helm, K. (1988) Human immunodeficiency virus has an aspartic-type protease that can be inhibited by pepstatin A. Proc. Natl. Acad. Sci. USA 85, 6612-6616.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 6612-6616
-
-
Seelmeier, S.1
Schmidt, H.2
Turk, V.3
Von Der Helm, K.4
-
41
-
-
85030188087
-
In vitro and in vivo activity of HIV protease inhibitors in an animal retrovirus model
-
Florence. Abstract No. WA68
-
Ussery, M.A., Black, P.L., Downs, M.B., Lewis, M.G., Lambert, D.M., Dreyer, G.B., Petteway, S.R., Jr. (1991) In vitro and in vivo activity of HIV protease inhibitors in an animal retrovirus model. VII International Conference on AIDS, Florence. Abstract No. WA68.
-
(1991)
VII International Conference on AIDS
-
-
Ussery, M.A.1
Black, P.L.2
Downs, M.B.3
Lewis, M.G.4
Lambert, D.M.5
Dreyer, G.B.6
Petteway S.R., Jr.7
-
42
-
-
0024412506
-
Conserved folding in retro viral proteases: Crystal structure of a synthetic HIV-1 protease
-
Wlodawer, A., Miller, M., Jaskolski, M., Sathyanarayana, B.K., Baldwin, E., Weber, I.T., Selk, L.M., Clawson, L., Schneider, J. and Kent, S.B. (1989) Conserved folding in retro viral proteases: Crystal structure of a synthetic HIV-1 protease. Science 245, 616-621.
-
(1989)
Science
, vol.245
, pp. 616-621
-
-
Wlodawer, A.1
Miller, M.2
Jaskolski, M.3
Sathyanarayana, B.K.4
Baldwin, E.5
Weber, I.T.6
Selk, L.M.7
Clawson, L.8
Schneider, J.9
Kent, S.B.10
-
43
-
-
0023922704
-
The spleen focus-forming virus (SFFV) envelope gene, when introduced into mice in the absence of other SFFV genes, induces acute erythroleukemia
-
Wolff, L. and Ruscetti, S. (1988) The spleen focus-forming virus (SFFV) envelope gene, when introduced into mice in the absence of other SFFV genes, induces acute erythroleukemia. J. Virol. 62, 2158-2163.
-
(1988)
J. Virol.
, vol.62
, pp. 2158-2163
-
-
Wolff, L.1
Ruscetti, S.2
|