Highly potent inhibitors of TNF-α production. Part 1: Discovery of chemical leads

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 6, 2002, Pages 903-905

  Matsui, Toshiaki ^a   Kondo, Takashi ^a   Nishita, Yoshitaka ^a   Itadani, Satoshi ^a   Nakatani, Shingo ^a   Omawari, Nagashige ^a   Sakai, Masaru ^a   Nakazawa, Shuichi ^a   Ogata, Akihito ^a   Ohno, Hiroyuki ^a   Obata, Takaaki ^a   Nakai, Hisao ^a   Toda, Masaaki ^a  

^a ONO PHARMACEUTICAL CO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLAMINE DERIVATIVE; IMMUNOLOGICAL ADJUVANT; LIPOPOLYSACCHARIDE; PHOSPHATE; TUMOR NECROSIS FACTOR ALPHA; DISODIUM HYDROGEN PHOSPHATE; PROTEIN SYNTHESIS INHIBITOR;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; CHEMISTRY; DRUG ANTAGONISM; MALE; METABOLISM; MOUSE; RAT; SPRAGUE DAWLEY RAT; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS; ANIMAL EXPERIMENT; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG ACTIVITY; DRUG POTENCY; NONHUMAN;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; BENZYLAMINES; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, INBRED BALB C; PHOSPHATES; RATS; RATS, SPRAGUE-DAWLEY; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR NECROSIS FACTOR-ALPHA;

EID: 18344390232     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00036-7     Document Type: Article

References (13)