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Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 8, 2002, Pages 1203-1208

Non-covalent thrombin inhibitors featuring P3-heterocycles with P1-monocyclic arginine surrogates

(15) Reiner, John E a Siev, Daniel V a Araldi, Gian Luca a Cui, Jingrong Jean a Ho, Jonathan Z a Reddy, Komandla Malla a Mamedova, Lala a Vu, Phong H a Lee, Kuen Shan S a Minami, Nathaniel K a Gibson, Tony S a Anderson, Susanne M a Bradbury, Annette E a Nolan, Thomas G a Semple, J Edward a

a Dendreon (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2,6 DIETHYLANILINO) 2 IMIDAZOLINE; AMIDINE; AMINE; ARGININE DERIVATIVE; AROMATIC AMIDE; HETEROCYCLIC COMPOUND; NC 1; NC 10; NC 11; NC 12; NC 13; NC 14; NC 15; NC 16; NC 17; NC 18; NC 19; NC 2; NC 20; NC 21; NC 22; NC 23; NC 24; NC 25; NC 26; NC 27; NC 28; NC 29; NC 3; NC 30; NC 4; NC 6; NC 8; NC 9; PYRAZINE DERIVATIVE; PYRIMIDINE DERIVATIVE; THROMBIN INHIBITOR;

ANIMAL EXPERIMENT; ARTICLE; CHIRALITY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BIOAVAILABILITY; DRUG DESIGN; DRUG SYNTHESIS; NONHUMAN;

ANIMALS; ANTITHROMBINS; ARGININE; DOGS; HETEROCYCLIC COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 18344370592 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/S0960-894X(02)00129-4 Document Type: Article

Times cited : (38)

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