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Volumn 539, Issue 1-2, 2005, Pages 133-140

Real-time monitoring of a pharmaceutical process reaction using a membrane interface combined with atmospheric pressure chemical ionisation mass spectrometry

(3) Clinton, Rebecca a Creaser, Colin S a Bryant, Duncan b

a NOTTINGHAM TRENT UNIVERSITY (United Kingdom)

b GLAXOSMITHKLINE (United Kingdom)

Author keywords

APCI MS; Membrane interface; Michael addition reaction; Process monitoring

Indexed keywords

ATMOSPHERIC PRESSURE; DRUG PRODUCTS; INTERFACES (MATERIALS); IONIZATION; ONLINE SYSTEMS; REACTION KINETICS; REAL TIME SYSTEMS;

ACRYLONITRILE; ATMOSPHERIC PRESSURE CHEMICAL IONIZATION (APCI); PHARMACEUTICAL PROCESS REACTION; QUADRUPOLE MASS SPECTROMETRY;

MASS SPECTROMETRY;

ACRYLONITRILE; ALCOHOL; PHENETHYLAMINE; POLYVINYLIDENE FLUORIDE;

ACCURACY; ARTICLE; CHEMICAL REACTION; CONCENTRATION (PARAMETERS); DEVICE; DILUTION; HYDROPHOBICITY; MASS SPECTROMETER; MASS SPECTROMETRY; MATERIALS; MEMBRANE; MICHAEL ADDITION; MONITORING; ONLINE ANALYSIS; POROSITY; PRECURSOR; PRIORITY JOURNAL; REACTION ANALYSIS; SAMPLE; TIME;

EID: 18344366356 PISSN: 00032670 EISSN: None Source Type: Journal
DOI: 10.1016/j.aca.2005.03.006 Document Type: Article

Times cited : (30)

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