Evidence for myocardial synthesis of aldosterone producing myocardial fibrosis in man

Clinical Science

Volumn 102, Issue 4, 2002, Pages 387-

  Struthers, Allan D ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; ALDOSTERONE SYNTHASE; COLLAGEN;

ADRENAL CORTEX; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE BIOPSY; HEART MUSCLE FIBROSIS; HORMONE ACTION; HORMONE SYNTHESIS; HUMAN; NOTE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

ALDOSTERONE; ENDOMYOCARDIAL FIBROSIS; HUMANS; MYOCARDIUM;

EID: 18344365008     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20010347     Document Type: Note

References (4)

1. The effect of spironolactone on morbidity and mortality in patients with severe heart failure
2. Aldosterone production is activated in failing ventricle in humans
3. Aldosterone synthase (CYP11B2) expression and myocardial fibrosis in the failing human heart
4. Spironolactone improves nitric oxide bioactivity, endothelial dysfunction and reduces vascular angiotensin I/angiotensin II conversion in patients with chronic heart failure