Synthesis and structure-activity relationship of 2-(aminoalkyl)-2,3,3a,8-tetrahydrodibenzo[c,f]isoxazolo[2,3-a]azepine derivatives: A novel series of 5-HT2A/2C receptor antagonists. Part 2

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 2, 2002, Pages 249-253

  Ignacio Andres J ^a   Alcázar, Jesús ^a   Alonso, José M ^a   Díaz, Adolfo ^a   Fernández, Javier ^a   Gil, Pilar ^a   Iturrino, Laura ^a   Matesanz, Encarna ^a   Meert, Theo F ^b   Megens, Anton ^b   Sipido, Victor K ^b  

^a Division of Janssen Cilag SA   (Spain)

^b JANSSEN RESEARCH FOUNDATION   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

(3 CHLOROPHENYL)PIPERAZINE; 2,3,3A,8 TETRAHYDRODIBENZ[C,F]ISOXAZOL[2,3 A]AZEPINE; ANXIOLYTIC AGENT; AZEPINE DERIVATIVE; HISTAMINE H1 RECEPTOR ANTAGONIST; SEROTONIN 2A ANTAGONIST; SEROTONIN 2A RECEPTOR; SEROTONIN 2C ANTAGONIST; SEROTONIN 2C RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY NEUROSIS; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG INDUSTRY; DRUG PROGRAM; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MALE; NONHUMAN; PROVOCATION TEST; RAT; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

AZEPINES; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTOR, SEROTONIN, 5-HT2C; RECEPTORS, SEROTONIN; SEROTONIN ANTAGONISTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 18244395895     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00722-3     Document Type: Article

References (23)