Synthesis and biological evaluation of gemcitabine-lipid conjugate (NEO6002)

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 10, 2005, Pages 2571-2574

  Ali, Shoukath M ^a   Khan, Abdul R ^a   Ahmad, Moghis U ^a   Chen, Paul ^a   Sheikh, Saifuddin ^a   Ahmad, Imran ^a  

^a NeoPharm Inc   (United States)

Author keywords

Cardiolipin; Gemcitabine; Lipid nucleoside conjugate; Prodrug

Indexed keywords

CARDIOLIPIN; GEMCITABINE; NEO 6002; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG EFFICACY; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PANCREAS TUMOR; SCID MOUSE;

EID: 18244395551     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.03.046     Document Type: Article

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22. 3): δ 4.26-4.14 (m, 8H); 4.09-4.07 (m, 2H); 3.79 and 3.77 (m, 6H); 3.63, 3.57, 3.52 and 3.46 (each m, 13H), 2.66 (m, 4H), 1.55 (m, 8H), 1.29 (m, 24H); 0.89 (t, J = 12 Hz, 12H)
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