Novel cytosolic binding partners of the neural cell adhesion molecule: Mapping the binding domains of PLCγ, LANP, TOAD-64, syndapin, PP1, and PP2A

Biochemistry

Volumn 44, Issue 18, 2005, Pages 6938-6947

  Büttner, Bettina ^a   Kannicht, Christoph ^b,c   Reutter, Werner ^a   Horstkorte, Rüdiger ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b Octapharma Pharmazeutika Produktions GmbH   (Austria)

^c PCR+D Molecular Biochemistry Berlin   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AFFINITY CHROMATOGRAPHY; BIOASSAY; BIOCHEMISTRY; ESCHERICHIA COLI; LIVING SYSTEMS STUDIES; NEUROLOGY; PROTEINS;

CYTOPLASMIC DOMAINS; FUSION PROTEINS; NEURAL CELL ADHESION MOLECULE (NCAM); TRANSMEMBRANE GLYCOPROTEINS;

CELLS;

ALPHA TUBULIN; BETA TUBULIN; BINDING PROTEIN; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; LEUCINE RICH ACIDIC NUCLEAR PROTEIN; NERVE CELL ADHESION MOLECULE; NEURAL CELL ADHESION MOLECULE 140; NEURAL CELL ADHESION MOLECULE 180; NUCLEAR PROTEIN; PHOSPHOLIPASE C GAMMA; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN TOAD 64; RHO KINASE; SYNDAPIN; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ARTICLE; CONTROLLED STUDY; CYTOSKELETON; CYTOSOL; ESCHERICHIA COLI; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; CARRIER PROTEINS; CYTOSOL; HUMANS; INTRACELLULAR FLUID; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MOLECULAR WEIGHT; NERVE TISSUE PROTEINS; NEURAL CELL ADHESION MOLECULES; NEUROPEPTIDES; NUCLEAR PROTEINS; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHOPROTEINS; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; RATS;

ESCHERICHIA COLI;

EID: 18244394543     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi050066c     Document Type: Article

References (40)

1. Thiery, J. P., et al. (1977) Adhesion among neural cells of the chick embryo. II. Purification and characterization of a cell adhesion molecule from neural retina, J. Biol. Chem. 252 (19), 6841-6845.
2. Edelman, G. M. (1985) Cell adhesion and the molecular processes of morphogenesis, Annu. Rev. Biochem. 54, 135-169.
3. Müller, D., et al. (1996) PSA-NCAM is required for activity-induced synaptic plasticity, Neuron 17 (3), 413-422.
4. Cremer, H., et al. (1994) Inactivation of the N-CAM gene in mice results in size reduction of the olfactory bulb and deficits in spatial learning, Nature 367 (6462), 455-459.
5. Olsen, M., et al. (1995) The ability to re-express polysialylated NCAM in soleus muscle after denervation is reduced in aged rats compared to young adult rats, Int. J. Dev. Neurosci. 13 (2), 97-104.
6. Owens, G. C., Edelman, G. M., and Cunningham, B. A. (1987) Organization of the neural cell adhesion molecule (N-CAM) gene: alternative exon usage as the basis for different membrane-associated domains, Proc. Natl. Acad. Sci. U.S.A. 84 (1), 294-298.
7. Goridis, C., et al. (1983) Neural surface antigens during nervous system development, Cold Spring Harbor Symp. Quant. Biol. 48 (Part 2), 527-537.
8. Pollerberg, E. G., et al. (1985) Selective expression of the 180-kD component of the neural cell adhesion molecule N-CAM during development, J. Cell Biol. 101 (5, Part 1), 1921-1929.
9. Little, E. B., Edelman, G. M., and Cunningham, B. A. (1998) Palmitoylation of the cytoplasmic domain of the neural cell adhesion molecule N-CAM serves as an anchor to cellular membranes, Cell Adhes. Commun. 6 (5), 415-430.
10. Niethammer, P., et al. (2002) Cosignaling of NCAM via lipid rafts and the FGF receptor is required for neuritogenesis, J. Cell Biol. 157(3), 521-532.
11. Doherty, P., and Walsh, F. S. (1996) CAM-FGF Receptor Interactions: A Model for Axonal Growth, Mol. Cell. Neurosci. 8 (2/3), 99-111.
12. Kiselyov, V. V., et al. (2003) Structural basis for a direct interaction between FGFR1 and NCAM and evidence for a regulatory role of ATP, Structure (Cambridge) 11 (6), 691-701.
13. Beggs, H. E., et al. (1997) NCAM140 interacts with the focal adhesion kinase p125(fak) and the SRC-related tyrosine kinase p59(fyn), J. Biol. Chem. 272 (13), 8310-8319.
14. Schmid, R. S., et al. (1999) NCAM stimulates the Ras-MAPK pathway and CREB phosphorylation in neuronal cells, J. Neurobiol. 38 (4), 542-558.
15. Jessen, U., et al. (2001) The transcription factors CREB and c-Fos play key roles in NCAM-mediated neuritogenesis in PC12-E2 cells, J. Neurochem. 79 (6), 1149-1160.
16. Ditlevsen, D. K., et al. (2003) The role of phosphatidylinositol 3-kinase in neural cell adhesion molecule-mediated neuronal differentiation and survival, J. Neurochem. 84 (3), 546-556.
17. Sorkin, B. C., et al. (1984) Sulfation and phosphorylation of the neural cell adhesion molecule, N-CAM, Science 225 (4669), 1476-1478.
18. Diestel, S., et al. (2004) Tyrosine 734 of NCAM180 interferes with FGF receptor-dependent signaling implicated in neurite growth, Biochem. Biophys. Res. Commun. 322 (1), 186-196.
19. Büttner, B., et al. (2003) The neural cell adhesion molecule is associated with major components of the cytoskeleton, Biochem. Biophys. Res. Commun. 310 (3), 967-971.
20. Büttner, B., Reutter, W., and Horstkorte, R. (2004) Cytoplasmic domain of NCAM 180 reduces NCAM-mediated neurite outgrowth, J. Neurosci. Res. 75 (6), 854-860.
21. Lucka, L., et al. (1995) A short isoform of carcinoembryonic-antigen- related rat liver cell-cell adhesion molecule (C-CAM/ gp110) mediates intercellular adhesion. Sequencing and recombinant functional analysis, Eur. J. Biochem. 234 (2), 527-535.
22. Falasca, M., et al. (1998) Activation of phospholipase C gamma by PI 3-kinase-induced PH domain-mediated membrane targeting, EMBO J. 17 (2), 414-422.
23. Katayose, Y., et al. (2000) Protein phosphatase 2A inhibitors, 1(1)-(PP2A) and I(2)(PP2A), associate with and modify the substrate specificity of protein phosphatase 1, J. Biol. Chem. 275 (13), 9209-9214.
24. Li, M., Makkinje, A., and Damuni, Z. (1996) Molecular identification of I1PP2A, a novel potent heat-stable inhibitor protein of protein phosphatase 2A. Biochemistry 35 (22), 6998-7002.
25. Kobe, B., and Deisenhofer, J. (1994) The leucine-rich repeat: a versatile binding motif, Trends Biochem. Sci. 19 (10), 415-421.
26. Kobe, B., and Deisenhofer, J. (1995) Proteins with leucine-rich repeats, Curr. Opin. Struct. Biol. 5 (3), 409-416.
27. Matsuoka, K., et al. (1994) A nuclear factor containing the leucine-rich repeats expressed in murine cerebellar neurons, Proc. Natl. Acad. Sci. U.S.A. 91 (21), 9670-9674.
28. Opal, P., et al. (2003) Mapmodulin/leucine-rich acidic nuclear protein binds the light chain of microtubule-associated protein 1B and modulates neuritogenesis, J. Biol. Chem. 278 (36), 34691-34699.
29. Ulitzur, N., Rancano, C., and Pfeffer, S. R. (1997) Biochemical characterization of mapmodulin, a protein that binds microtubule-associated proteins, J. Biol. Chem. 272 (48), 30577-30582.
30. Ulitzur, N., Humbert, M., and Pfeffer, S. R. (1997) Mapmodulin: a possible modulator of the interaction of microtubule-associated proteins with microtubules, Proc. Natl. Acad. Sci. U.S.A. 94 (10), 5084-5089.
31. Bollen, M. (2001) Combinatorial control of protein phosphatase-1, Trends Biochem Sci 26 (7), 426-431.
32. Mackie, K., et al. (1989) Identification of two protein kinases that phosphorylate the neural cell-adhesion molecule, N.-CAM, J. Neurosci. 9 (6), 1883-1896.
33. Arimura, N., et al. (2000) Phosphorylation of collapsin response mediator protein-2 by Rho-kinase. Evidence for two separate signaling pathways for growth cone collapse, J. Biol. Chem. 275 (31), 23973-23980.
34. Quinn, C. C., Gray, G. E., and Hockfield, S. (1999) A family of proteins implicated in axon guidance and outgrowth, J. Neurobiol. 41 (1), 158-164.
35. Geschwind, D. H., et al. (1996) Identification and characterization of novel developmentally regulated proteins in rat spinal cord, Brain Res. Dev. Brain Res. 97 (1), 62-75.
36. Minturn, J. E., et al. (1995) TOAD-64, a gene expressed early in neuronal differentiation in the rat, is related to unc-33, a C. elegans gene involved in axon outgrowth, J. Neurosci. 15 (10), 6757-6766.
37. Qualmann, B., et al. (1999) Syndapin I, a synaptic dynamin-binding protein that associates with the neural Wiskott-Aldrich syndrome protein, Mol. Biol. Cell 10 (2), 501-513.
38. Qualmann, B., and Kelly, R. B. (2000) Syndapin isoforms participate in receptor-mediated endocytosis and actin organization, J. Cell Biol. 148 (5), 1047-1062.
39. Minana, R., et al. (2001) Neural cell adhesion molecule is endocytosed via a clathrin-dependent pathway, Eur. J. Neurosci. 13 (4), 749-756.
40. Sekiya, F., Bae, Y. S., and Rhee, S. G. (1999) Regulation of phospholipase C isozymes: activation of phospholipase C-gamma in the absence of tyrosine-phosphorylation, Chem. Phys. Lipids 98 (1-2), 3-11.