Disorganization of the facial nucleus after nerve lesioning and regeneration in the rat: Effects of transplanting candidate reparative cells to the site of injury

Neurosurgery

Volumn 56, Issue 5, 2005, Pages 1093-1099

  Choi, David ^a   Raisman, Geoffrey ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

Facial nerve; Regeneration; Somatotopy; Synkinesis; Transplantation

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL TRANSPLANTATION; CONTROLLED STUDY; EYELID CLOSURE; FACIAL NERVE INJURY; FACIAL NERVE NUCLEUS; FACIAL NERVE SURGERY; FEMALE; FLUORESCENCE; FUNCTIONAL ASSESSMENT; HISTOLOGY; NERVE REGENERATION; NEUROPATHOLOGY; NONHUMAN; OLFACTORY ENSHEATHING CELL; PRIORITY JOURNAL; RAT; SCHWANN CELL; SUTURE;

ANIMALS; DISEASE MODELS, ANIMAL; FACIAL NERVE INJURIES; FEMALE; NERVE REGENERATION; NEURONS; OCULAR PHYSIOLOGY; OPTIC NERVE; RATS; RATS, INBRED STRAINS;

EID: 18244387720     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1227/01.NEU.0000158201.30322.2C     Document Type: Article

References (34)

1. Aldskogius H, Thomander L: Selective reinnervation of somatotopically appropriate muscles after facial nerve transection and regeneration in the neonatal rat. Brain Res 375:126-134, 1986.
2. Angelov DN, Neiss WF, Streppel M, Andermahr J, Mader K, Stennert E: Nimodipine accelerates axonal sprouting after surgical repair of rat facial nerve. J Neurosci 16:1041-1048, 1996.
3. Asahara T, Lin M, Kumazawa Y, Takeo K, Akamine T, Nishimura Y, Kayahara T, Yamamoto T: Long-term observation on the changes of somatotopy in the facial nucleus after nerve suture in the cat: Morphological studies using retrograde labeling. Brain Res Bull 49:195-202, 1999.
4. Barnett SC, Hutchins AM, Noble M: Purification of olfactory nerve ensheathing cells from the olfactory bulb. Dev Biol 155:337-350, 1993.
5. Byers JM, Clark KF, Thompson GC: Effect of pulsed electromagnetic stimulation on facial nerve regeneration. Arch Otolaryngol Head Neck Surg 124:383-389, 1998.
6. Chen YS, Murakami S, Gyo K, Wakisaka H, Matsuda S, Sakanaka M: Effects of basic fibroblast growth factor (bFGF)-neutralizing antibody and platelet factor 4 on facial nerve regeneration. Exp Neurol 155:274-283, 1999.
7. Choi D, Dunn LT: Facial nerve repair and regeneration: An overview of basic principles for neurosurgeons. Acta Neurochir (Wien) 143:107-114, 2001.
8. Choi D, Raisman G: Somatotopic organization of the facial nucleus is disrupted after lesion and regeneration of the facial nerve: The histological representation of synkinesis. Neurosurgery 50:355-363, 2002.
9. Choi D, Li D, Raisman G: Fluorescent retrograde neuronal tracers that label the rat facial nucleus: A comparison of Fast Blue, Fluoro-ruby, Fluoro-emerald, Fluoro-Gold and Dil. J Neurosci Methods 117:167-172, 2002.
10. Cummings DM, Emge DK, Small SL, Margolis FL: Pattern of olfactory bulb innervation returns after recovery from reversible peripheral deafferentation. J Comp Neurol 421:362-373, 2000.
11. Dohm S, Streppel M, Guntinas-Lichius O, Pesheva P, Probstmeier R, Walther M, Neiss WF, Stennert E, Angelov DN: Local application of extracellular matrix proteins fails to reduce the number of axonal branches after varying reconstructive surgery on rat facial nerve. Restor Neurol Neurosci 16:117-126, 2000.
12. Dort JC, Wolfensberger M, Felix H: CO2 laser repair of the facial nerve: An experimental study in the rat. J Laryngol Otol 108:466-469, 1994.
13. Eddleston M, Mucke L: Molecular profile of reactive astrocytes: Implications for their role in neurologic disease. Neuroscience 54:15-36, 1993.
14. Fernandez E, Pallini R, Marchese E, Lauretti L, La Marca F: Quantitative, morphological, and somatotopic nuclear changes after facial nerve regeneration in adult rats: a possible challenge to the "no new neurons" dogma. Neurosurgery 37:456-462, 1995.
15. Gilad VH, Tetzlaff WG, Rabey JM, Gilad GM: Accelerated recovery following polyamines and aminoguanidine treatment after facial nerve injury in rats. Brain Res 724:141-144, 1996.
16. Gilchrist T, Glasby MA, Healy DM, Kelly G, Lenihan DV, McDowall KL, Miller IA, Myles LM: In vitro nerve repair in vivo: The reconstruction of peripheral nerves by entubulation with biodegradable glass tubes - A preliminary report. Br J Plast Surg 51:231-237, 1998.
17. Glasby MA, Clutton RE, Drew SJ, O'Sullivan MG, Whittle IR: Repair of the facial nerve in the cerebellopontine angle using freeze-thawed skeletal muscle autografts: An experimental surgical study in the sheep. Acta Neurochir (Wien) 136:151-159, 1995.
18. Guntinas-Lichius O, Angelov DN, Tomov TL, Dramiga J, Neiss WF, Wewetzer K: Transplantation of olfactory ensheathing cells stimulates the collateral sprouting from axotomized adult rat facial motoneurons. Exp Neurol 172:70-80, 2001.
19. Guntinas-Lichius O, Neiss WF, Gunkel A, Stennert E: Differences in glial, synaptic and motoneuron responses in the facial nucleus of the rat brainstem following facial nerve resection and nerve suture reanastomosis. Eur Arch Otorhinolaryngol 251:410-417, 1994.
20. Ito M, Kudo M: Reinnervation by axon collaterals from single facial motoneurons to multiple muscle targets following axotomy in the adult guinea pig. Acta Anat (Basel) 151:124-130, 1994.
21. Ito M, Okoyama S, Furukawa M, Kitao Y, Moriizumi T, Kudo M: Non-selective reinnervation by regenerating facial motoneurons after peripheral nerve crush in the developing rat. Kaibogaku Zasshi 69:168-174, 1994.
22. Li Y, Raisman G: Schwann cells induce sprouting in motor and sensory axons in the adult rat spinal cord. J Neurosci 14:4050-4063, 1994.
23. Li Y, Field PM, Raisman G: Repair of adult rat corticospinal tract by transplants of olfactory ensheathing cells. Science 277:2000-2002, 1997.
24. Medders G, Mattox DE, Lyles A: Effects of fibrin glue on rat facial nerve regeneration. Otolaryngol Head Neck Surg 100:106-109, 1989.
25. Murray JA, Willins M, Mountain RE: A comparison of absorbable and non-absorbable 10-0 sutures for the repair of a divided rat facial nerve. Clin Otolaryngol 19:61-62, 1994.
26. Park HJ, Kim HN, Kim KM: Redistribution of facial nerve motor neurons after recovery from nerve crushing injury in the gerbil. Acta Otolaryngol (Stockh) 115:273-275, 1995.
27. Popratiloff AS, Neiss WF, Skouras E, Streppel M, Guntinas-Lichius O, Angelov DN: Evaluation of muscle re-innervation employing pre- and post-axotomy injections of fluorescent retrograde tracers. Brain Res Bull 54:101-113, 2001.
28. Ramon-Cueto A, Nieto-Sampedro M: Glial cells from adult rat olfactory bulb: Immunocytochemical properties of pure cultures of ensheathing cells. Neuroscience 47:213-220, 1992.
29. Rouleau M, Crepeau J, Tetreault L, Lamarche J: Facial nerve sutures: Epineural versus perineural sutures. J Otolaryngol 10:338-342, 1981.
30. Salzer JL, Bunge RP: Studies of Schwann cell proliferation: Part I - An analysis in tissue culture of proliferation during development, Wallerian degeneration, and direct injury J Cell Biol 84:739-752, 1980.
31. Spector JG, Lee P, Derby A, Roufa DG: Comparison of rabbit facial nerve regeneration in nerve growth factor-containing silicone tubes to that in autologous neural grafts. Ann Otol Rhinol Laryngol 104:875-885, 1995.
32. Szal GJ, Miller T: Surgical repair of facial nerve branches: An analysis of different sheathing and suturing techniques. Arch Otolaryngol 101:160-165, 1975.
33. Thomander L: Reorganisation of the facial motor nucleus after peripheral nerve regeneration: An HRP study in the rat. Acta Otolaryngol 97:619-626, 1984.
34. Tong JX, Rich KM: Diphenylpiperazines enhance regeneration after facial nerve injury. J Neurocytol 26:339-347, 1997.