3-Aryl pyridone derivatives. Potent and selective kappa opioid receptor agonists

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 2, 2002, Pages 197-200

  Semple, Graeme ^a   Andersson, Britt Marie ^a   Chhajlani, Vijay ^a   Georgsson, Jennie ^a   Johansson, Magnus ^a   Lindschoten, Marcel ^a   Pontén, Fritof ^a   Rosenquist, Åsa ^a   Sörensen, Henrik ^a   Swanson, Lars ^a   Swanson, Marianne ^a  

^a ASTRAZENECA R AND D   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2 CHLORO 2 PHENYLETHYL)PYRROLIDINE; 2 HYDROXYPYRIDINE; 3 BROMOPYRIDONE; 3 PHENYLPYRIDINE; KAPPA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR AGONIST; N METHYL N [7 (1 PYRROLIDINYL) 1 OXASPIRO[4.5]DEC 8 YL]BENZENEACETAMIDE; PYRIDINE DERIVATIVE; PYRIDONE DERIVATIVE; PYRROLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG DESIGN; DRUG EFFECT; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; PHARMACOPHORE; RECEPTOR AFFINITY;

HUMANS; PROTEIN BINDING; PYRIDONES; RECEPTORS, OPIOID, KAPPA;

EID: 18244375055     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00691-6     Document Type: Article

References (18)