Combination gene therapy for glioblastoma involving herpes simplex virus vector-mediated codelivery of mutant IκBα and HSV thymidine kinase

Cancer Gene Therapy

Volumn 12, Issue 5, 2005, Pages 487-496

  Moriuchi, Shusuke ^a,b   Glorioso, Joseph C ^c   Maruno, Motohiko ^a   Izumoto, Shuichi ^a   Wolfe, Darren ^c   Huang, Shaohua ^c   Cohen, Justus B ^c   Yoshimine, Toshiki ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA NATIONAL HOSPITAL   (Japan)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Glioma; Herpes simplex virus type 1; I B; NF B

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; BETA GALACTOSIDASE; CASPASE 3; DIMER; GANCICLOVIR; I KAPPA B ALPHA; MUTANT PROTEIN; PROTEIN P50; THYMIDINE KINASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER TRANSPLANTATION; CELL NUCLEUS; COLORIMETRY; CONTROLLED STUDY; CYTOTOXICITY; EMBRYO; ENZYME ACTIVITY; FEMALE; GEL MOBILITY SHIFT ASSAY; GENE; GENE EXPRESSION; GENE LOCUS; GENETIC RECOMBINATION; GLIOBLASTOMA; HERPES SIMPLEX VIRUS 1; LACZ GENE; MOUSE; NEUROTOXICITY; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SUICIDE GENE THERAPY; SURVIVAL RATE; VIRAL GENE DELIVERY SYSTEM; VIRUS REPLICATION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BRAIN; BRAIN NEOPLASMS; CASPASE 3; CASPASES; COMBINED MODALITY THERAPY; FEMALE; GENE THERAPY; GENES, TRANSGENIC, SUICIDE; GENETIC VECTORS; GLIOBLASTOMA; HERPESVIRUS 1, HUMAN; HUMANS; I-KAPPA B PROTEINS; MICE; MUTATION; PLASMIDS; THYMIDINE KINASE; TUMOR CELLS, CULTURED;

HERPES; HUMAN HERPESVIRUS 1; MURINAE; MUS MUSCULUS; SIMPLEXVIRUS;

EID: 18244372933     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cgt.7700816     Document Type: Article

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