Influence of cold ischemia time, pretransplant antiporcine antibodies, and donor/recipient size matching on hyperacute graft rejection after discordant porcine to cynomolgus kidney transplantation

Transplantation

Volumn 69, Issue 6, 2000, Pages 1155-1159

  Loss, M ^a   Kunz, R ^a   Przemeck, M ^a   Schmidtko, J ^a   Arends, H ^a   Jalali, A ^a   Lorenz, R ^a   Piepenbrock, S ^a   Klempnauer, J ^a   Winkler, M ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; COMPLEMENT ACTIVATION; CONTROLLED STUDY; GRAFT REJECTION; GRAFT SURVIVAL; IMMUNOHISTOCHEMISTRY; ISCHEMIA; MONKEY; NONHUMAN; ORGAN TRANSPLANTATION; PHYLOGENY; PRIORITY JOURNAL; REPERFUSION; XENOTRANSPLANTATION;

EID: 18144445030     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-200003270-00021     Document Type: Article

References (19)

1. Platt JL, Fischel RJ, Matas AJ, et al. Immunopathology of hyperacute xenograft rejection in a swine-to-primate model. Transplantation 1991; 52: 214.
2. Dalmasso AP, Vercellotti GM, Fischel RJ, et al. Mechanism of complement activation in the hyperacute rejection of porcine organs transplanted into primate recipients. Am J Pathol 1992; 140: 1157.
3. Lawson JH, Platt JL. Molecular barriers to xenotransplantation. Transplantation 1996; 62: 303.
4. Calne RY. Organ transplantation between widely disparate species. Transplant Proc 1970; 2: 550.
5. Zaidi A, Schmoeckel M, Bhatti F, et al. Life-supporting pig-to-primate renal xenotransplantation using genetically modified donors. Transplantation 1998; 65: 1584.
6. Zaidi A, Friend P, Schmoeckel M, et al. Hyperacute rejection is not consistent after pig to primate renal xenotransplantation. Transplant Proc 1999 (in press).
7. Sablinski T, Gianello PR, Bailin M, et al. Pig to monkey bone marrow and kidney xenotransplantation. Surgery 1997; 121: 381.
8. Davis EA, Pruitt SK, Greene PS, et al. Inhibition of complement, evoked antibody, and cellular response prevents rejection of pig-to-primate cardiac xenografts. Transplantation 1996; 62: 1018.
9. Waterworth PD, Cozzi E, Tolan MJ, et al. Pig-to-primate cardiac xenotransplantation and cyclophosphamide therapy. Transplant Proc 1997; 29: 899.
10. Fraiser LH, Kanekal S, Kehrer JP. Cyclophosphamide toxicity: characterizing and avoiding the problem. Drugs 1991; 42: 781.
11. Xu Y, Lorf T, Sablinski T, et al. Removal of anti-porcine natural antibodies from human and nonhuman primate plasma in vitro and in vivo by a Galα1-3Galβ1-4βGlc-X immunoaffinity column. Transplantation 1998; 65: 172.
12. Michler RE, Xu H, O'Hair DP, et al. Newborn discordant cardiac xenotransplantation in primates: a model of natural antibody depletion. Transplant Proc 1996; 28: 651.
13. Minanov OP, Itescu S, Neethling FA, et al. Anti-Gal IgG antibodies in sera of newborn humans and baboons and its significance in pig xenotransplantation. Transplantation 1997; 63: 182.
14. Sandrin MS, Vanghem HA, Dabkouski PL, McKenzie IF. Anti-pig IgM antibodies in human serum react predominantly with Gal (alpha1-3) Gal epitopes. Proc Natl Acad Sci USA 1993; 23: 11391.
15. Platt JL, Vercellotti GM, Dalmasso AP, et al. Transplantation of discordant xenografts: a review of progress. Immunol Today 1990; 11: 450.
16. Hoopes CW, Platt JL. Molecular strategies for clinical xenotransplantation in cardiothoracic surgery. Semin Thorac Cardiovasc Surg 1996; 8: 156.
17. Besse T, Duck D, Latienne D, et al. Effect of plasmapheresis and splenectomy on parameters involved in vascular rejection of discordant xenografts in the swine to baboon model. Transplant Proc 1994; 26: 1042.
18. Leventhal JR. Removal of natural antibodies by immunoabsorption: Results of experimental studies. In: Cooper DKC, Kemp E, Platt JL, White, DJG, eds Xenotransplantation: the transplantation of organs and tissues between species. Berlin: Springer-Verlag 1997; 360.
19. Shapiro R, Tzakis AG, Scantlebury V, et al. Immunodepletion in xenotransplantation. J Invest Surg 1990; 3: 39.