Tableting and stability evaluation of enteric-coated omeprazole pellets

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 57, Issue 2, 2004, Pages 279-286

  Türkoǧlu, Murat ^a   Varol, Hakan ^a   Çelikok, Mine ^a  

^a MARMARA UNIVERSITY   (Turkey)

Author keywords

Accelerated stability; Artificial neural networks; Omeprazole; Pellet compression; Pellets

Indexed keywords

MACROGOL 6000; MICROCRYSTALLINE CELLULOSE; OMEPRAZOLE; STARCH; STARCH GLYCOLATE SODIUM;

ANALYSIS OF VARIANCE; ARTICLE; ARTIFICIAL NEURAL NETWORK; CORRELATION ANALYSIS; DATA ANALYSIS; DRUG DEGRADATION; DRUG SCREENING; DRUG STABILITY; ENTERIC COATED TABLET; FLUIDIZED BED; MOLECULAR MODEL; PELLET EXTRUSION; SURFACE PROPERTY; TABLET; TABLET FORMULATION;

EID: 18144437004     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2003.10.008     Document Type: Article

References (10)

1. Maganti L., Çelik M. Compaction studies on pellets: II. Coated pellets. Int. J. Pharm. 103:1994;55-67.
2. Beckert T.E., Lehmann K., Schmidt P.C. Compression of enteric-coated pellets to disintegrating tablets. Int. J. Pharm. 143:1996;13-23.
3. Wagner K.G., Krumme M., Schmidt P.C. Pellet-containing tablets examination of distribution and deformation behaviour. STP Pharm Sci. 10:2000;327-334.
4. Beckert T.E., Lieneweg M. Compression of enteric-coated pellets: flexible enteric film coatings with propylene glycol as a plasticizer for Eudragit L 30 D-55. 28th International Symposium on Controlled Release of Bioactive Materials and Fourth Consumer and Diversified Product Conference, June 23-27, 2001 San Diego, CA, USA. 2001.
5. Lefranc A., Chenevier P., Demay M.C., Suplie P. Influence of plasticiser and coating levels on damage of coated pellets in multiple unit tablet. 28th International Symposium on Controlled Release of Bioactive Materials and Fourth Consumer and Diversified Product Conference, June 23-27, 2001 San Diego, CA, USA. 2001.
6. Mathew M., Gupta V.D., Bailey E.R. Stability of omeprazole solutions at various pH values as determined by HPLC. Drug Dev. Ind. Pharm. 21:1995;965-971.
7. Davidson A.G., McCallum A. A survey of the stability of omeprazole products from 13 countries. Drug Dev. Ind. Pharm. 22:1996;1173-1185.
8. Storpirtis S., Rodrigues D. In vitro evaluation of dissolution properties and degradation products of omeprazole in enteric coated pellets. Drug Dev. Ind. Pharm. 24:1998;1101-1107.
9. Turkoglu M., Nirun E., Yeniyurt M. A modified laboratory size rotary fluidized-bed for pharmaceutical solid materials processing. Pharm. Engng. 19:1999;70-77.
10. Turkoglu M., Ozarslan R., Sakr A. Artificial neural network analysis of a direct compression tabletting study. Eur. J. Pharm. Biopharm. 41:1995;315-322.