The ophthalmic lyophilisate carrier system (OLCS): Development of a novel dosage form, freeze-drying technique, and in vitro quality control tests

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 57, Issue 2, 2004, Pages 269-277

  Süverkrüp, Richard ^a   Grunthal, Sabine ^a   Krasichkova, Olena ^a   Maier, Stephan ^a   Weichselbaum, Anja ^a   Neff, Bernd ^a   Diestelhorst, Michael ^b   Dinslage, Sven ^b   Lux, Anja ^b  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Adhesive strength; Bioavailability; Freezing rate; Laser fluorimetry; Lyophilization; Ophthalmic drug delivery; Pupillometry

Indexed keywords

DRUG CARRIER; EXCIPIENT; EYE DROPS; FLUORESCEIN; HYDROXYPROPYLMETHYLCELLULOSE; METHYLCELLULOSE; PILOCARPINE; TROPICAMIDE;

ADHESION; ANTERIOR EYE CHAMBER; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORNEA; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM; DRUG SOLUBILITY; DRUG TOLERABILITY; EYE; FREEZE DRYING; HUMAN; HYDROPHOBICITY; LYOPHILISATE; QUALITY CONTROL; TEAR FILM; VALIDATION PROCESS; VOLUNTEER;

EID: 18144432762     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(03)00190-5     Document Type: Article

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