Anti-HIV protease activity from Rosa family plant extracts and rosamultin from Rosa rugosa

Journal of Medicinal Food

Volumn 8, Issue 1, 2005, Pages 107-109

  Park, Jong Cheol ^a   Kim, Sang Chul ^a   Choi, Myeong Rak ^b   Song, Sang Ho ^b   Yoo, Eun Jeong ^b   Kim, Sung Hwan ^c   Miyashiro, Hirotsugu ^d   Hattori, Masao ^d  

^a Sunchon National University   (South Korea)

^b Chonnam National University   (South Korea)

^c Kyongbuk Inst of Hlth and Environ   (South Korea)

^d UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Human immunodeficiency virus 1 protease; Protease inhibitor; Prunus sargentii; Rosa family plant; Rosa rugosa; Rosamultin

Indexed keywords

CATECHIN; GALLIC ACID; GALLIC ACID METHYL ESTER; HYPERIN; KAJI ICHIGOSIDE F1; PLANT EXTRACT; PROTEINASE; PRUNUS PERSICA EXTRACT; PRUNUS SARGENTII EXTRACT; QUERCETIN; ROSA ACICULARIS EXTRACT; ROSA MAXIMOWICZIANA EXTRACT; ROSA RUGOSA EXTRACT; ROSA WICHURAIANA EXTRACT; ROSAMULTIN; RUBUS CORCHORIFOLIUS EXTRACT; RUBUS CRATAEGIFOLIUS EXTRACT; SORBUS ALNIFOLIA EXTRACT; STEPHANADRA INCISA EXTRACT; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG STRUCTURE; HUMAN IMMUNODEFICIENCY VIRUS; NONHUMAN; PLANT LEAF; PLANT ROOT; PRIORITY JOURNAL; PRUNUS; PRUNUS PERSICA; PRUNUS SARGENTII; ROSA ACICULARIS; ROSA MAXIMOWICZIANA; ROSA RUGOSA; ROSA WICHURAIANA; ROSE; RUBUS CORCHORIFOLIUS; RUBUS CRATAEGIFOLIUS; SORBUS ALNIFOLIA; STEPHANADRA INCISA; VIRUS INHIBITION;

ANTI-HIV AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; HIV INFECTIONS; HIV PROTEASE; HIV PROTEASE INHIBITORS; HIV-1; HUMANS; PHYTOTHERAPY; PLANT EXTRACTS; ROSA; TREATMENT OUTCOME; TRITERPENES;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; PRUNUS; PRUNUS PERSICA; PRUNUS SARGENTII; ROSA; ROSA ACICULARIS; ROSA MAXIMOWICZIANA; ROSA RUGOSA; ROSA WICHURANA; RUBUS CORCHORIFOLIUS; RUBUS CRATAEGIFOLIUS; SORBUS; SORBUS ALNIFOLIA;

EID: 18144427474     PISSN: 1096620X     EISSN: None     Source Type: Journal    
DOI: 10.1089/jmf.2005.8.107     Document Type: Article

References (17)

1. Kohl NE, Emini EA, Schleif WA, Davis LJ, Heimbach JC, Dixon RAF, Scolnick EM, Sigal IS: Active human immunodeficiency virus protease is required for viral infectivity. Proc Natl Acad Sci U S A 1988;85:4686-4690.
2. Young HS, Park JC, Choi JS: Triterpenoid glycosides from Rosa rugosa. Arch Pharm Res 1987;10:219-222.
3. Young HS, Park JC, Choi JS: Isolation of (+)-catechin from the roots of Rosa rugosa. Korean J Pharmacogn 1987;18:177-179.
4. Park JC, Ok KD: Phenolic compounds isolated from Rosa rugosa in Korea. Yakhak Hoeji (J Pharm Sci Korea) 1993;37:365-369.
5. Kusumoto IT, Nakabayashi T, Kida H, Miyashiro H, Hattori M, Namba T, Shimotohno K: Screening various plants extracts used in Ayurvedic medicine for inhibitory effects on human immunodeficiency virus type 1 protease. Phytother Res 1995;9:180-184.
6. Leis J, Baltimore D, Bishop JM, Coffin J, Fleissner E, Goff SP, Oroszlan S, Robinson H, Skalka AM, Temin HM, Vogt V: Standardized and simplified nomenclature for proteins common to all retroviruses. J Virol 1988;62:1808-1809.
7. Jacks T, Power MD, Masiarz FR. Luciw PA, Barr PJ, Varmus HE: Characterization of ribosomal frameshifting in HIV-1 gagpol expression. Nature 1988;331:280-283.
8. Farmerie WG, Loeb DD, Casavant NC, Hutchison CA, Edgell MH, Swanstrom R: Expression and processing of the AIDS virus reverse transcriptase in Escherichia coli. Science 1987;236:305-308.
9. Peng C, Ho BK, Chang TW, Chang NT: Role of human immunodeficiency virus type 1-specific protease in core protein maturation and viral infectivity. J Virol 1989;63:2550-2556.
10. Song SO, Kim KH, Kang DH: Effect of tap Japanese rose root-extract on the blood level in rat. Yonsei J Med Sci 1977;10:125-128.
11. Choi YS, Ahn C, Jhoo JW, Park JC, Lee SY: Effect of Rosa rugosa radix on lipid metabolism in rats. Korean J Biotechnol Bioeng 1993;8:224-229.
12. Lee SY, Kim JD, Lee YH, Rhec HI, Choi YS: Influence of extract of Rosa rugosa roots on lipid levels in scrum and liver of rats. Life Sci 1991;49:947-951.
13. Young HS, Park JC, Choi JS, Chung HY: The serum cholesterol level lowering effect from the undergrund parts of Rosa rugosa. Yakhak Hoeji (J Pharm Soc Korea) 1987;31:394-398.
14. Cho EJ, Yokozawa T, Rhyu DY, Kim SC, Shibahara N, Park JC: Study on the inhibitory effects of Korean medicinal plants and their main compounds on the 1,1-diphenyl-2-picrylhydrazyl radical. Phytomedicine 2003;10:544-551.
15. Xu HX, Zeng FQ, Wan M, Sim KY: Anti-HIV triterpene acids from Geum japonicum. J Nat Prod 1996;59:643-645.
16. Min BS, Jung HJ, Lee JS, Kim YH, Bok SH, Ma CM, Nakamura N, Hattori M, Bae KH: Inhibitory effect of triterpenes from Crataegus pinatifida on HIV-1 protease. Planta Med 1999;65:374-375.
17. Ma C, Nakamura N, Miyashiro H, Hattori M, Shimotohno K: Inhibitory effects of constituents from Cynomorium songaricum and related triterpene derivatives on HIV-1 protease. Chem Pharm Bull (Tokyo) 1999;47:141-145.