-
1
-
-
0026666791
-
Ordering gene function: The interpretation of epistasis in regulatory hierarchies
-
Avery, L. & Wasserman, S. Ordering gene function: the interpretation of epistasis in regulatory hierarchies. Trends Genet. 8, 312-316 (1992).
-
(1992)
Trends Genet.
, vol.8
, pp. 312-316
-
-
Avery, L.1
Wasserman, S.2
-
2
-
-
0037433043
-
GenePath: A system for automated construction of genetic networks from mutant data
-
Zupan, B. et al. GenePath: a system for automated construction of genetic networks from mutant data. Bioinformatics 19, 383-389 (2003).
-
(2003)
Bioinformatics
, vol.19
, pp. 383-389
-
-
Zupan, B.1
-
3
-
-
0037173615
-
Functional profiling of the Sacchammyces cerevisiae genome
-
Giaever, G. et al. Functional profiling of the Sacchammyces cerevisiae genome. Nature 418, 387-391 (2002).
-
(2002)
Nature
, vol.418
, pp. 387-391
-
-
Giaever, G.1
-
4
-
-
10744230485
-
Global mapping of the yeast genetic interaction network
-
Tong, A.M. et al. Global mapping of the yeast genetic interaction network. Science 303, 808-813 (2004).
-
(2004)
Science
, vol.303
, pp. 808-813
-
-
Tong, A.M.1
-
5
-
-
0033529707
-
Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis
-
Winzeler, E.A. et al. Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis. Science 285, 901-906 (1999).
-
(1999)
Science
, vol.285
, pp. 901-906
-
-
Winzeler, E.A.1
-
6
-
-
13044304179
-
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers
-
Perou, C.M. et al. Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Proc. Natl. Acad. Sci. USA 96, 9212-9217 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 9212-9217
-
-
Perou, C.M.1
-
7
-
-
0033569406
-
Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
-
Golub, T.R. et al. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science 286, 531-537 (1999).
-
(1999)
Science
, vol.286
, pp. 531-537
-
-
Golub, T.R.1
-
8
-
-
0032563315
-
Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors
-
Gray, N.S. et al. Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors. Science 281, 533-538 (1998).
-
(1998)
Science
, vol.281
, pp. 533-538
-
-
Gray, N.S.1
-
9
-
-
0032567081
-
Dissecting the regulatory circuitry of a eukaryotic genome
-
Holstege, F.C. et al. Dissecting the regulatory circuitry of a eukaryotic genome. Cell 95, 717-728 (1998).
-
(1998)
Cell
, vol.95
, pp. 717-728
-
-
Holstege, F.C.1
-
10
-
-
0034051902
-
Genomic-scale gene expression profiling of normal and malignant immune cells
-
Alizadeh, A.A. & Staudt, L.M. Genomic-scale gene expression profiling of normal and malignant immune cells. Curr. Opin. Immunol. 12, 219-225 (2000).
-
(2000)
Curr. Opin. Immunol.
, vol.12
, pp. 219-225
-
-
Alizadeh, A.A.1
Staudt, L.M.2
-
11
-
-
0034616930
-
Functional discovery via a compendium of expression profiles
-
Hughes, T.R. et al. Functional discovery via a compendium of expression profiles. Cell 102, 109-126 (2000).
-
(2000)
Cell
, vol.102
, pp. 109-126
-
-
Hughes, T.R.1
-
12
-
-
0034603061
-
Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles
-
Roberts, C.J. et al. Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles. Science 287, 873-880 (2000).
-
(2000)
Science
, vol.287
, pp. 873-880
-
-
Roberts, C.J.1
-
13
-
-
0035998870
-
Gene expression patterns in Dictyostelium using micro-arrays
-
Shaulsky, G. & Loomis, W.F. Gene expression patterns in Dictyostelium using micro-arrays. Protist 153, 93-98 (2002).
-
(2002)
Protist
, vol.153
, pp. 93-98
-
-
Shaulsky, G.1
Loomis, W.F.2
-
15
-
-
0031712268
-
Role of PKA in the timing of developmental events in Dictyostelium cells
-
Loomis, W.F. Role of PKA in the timing of developmental events in Dictyostelium cells. Microbiol. Mol. Biol. Rev. 62, 684 (1998).
-
(1998)
Microbiol. Mol. Biol. Rev.
, vol.62
, pp. 684
-
-
Loomis, W.F.1
-
16
-
-
0032767435
-
Starvation promotes Dictyostelium development by relieving PufA inhibition of PKA translation through the YakA kinase pathway
-
Souza, G.M., da Silva, A.M. & Kuspa, A. Starvation promotes Dictyostelium development by relieving PufA inhibition of PKA translation through the YakA kinase pathway. Development 126, 3263-3274 (1999).
-
(1999)
Development
, vol.126
, pp. 3263-3274
-
-
Souza, G.M.1
Da Silva, A.M.2
Kuspa, A.3
-
17
-
-
0030581603
-
Bootstrap confidence levels for phylogenetic trees
-
Efron, B., Halloran, E. & Holmes, S. Bootstrap confidence levels for phylogenetic trees. Proc. Natl. Acad. Sci. USA 93, 13429-13434 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 13429-13434
-
-
Efron, B.1
Halloran, E.2
Holmes, S.3
-
18
-
-
0000461280
-
Confidence limits on phytogenies: An approach using the bootstrap
-
Felsenstein, J. Confidence limits on phytogenies: an approach using the bootstrap. Evolution 39, 783-791 (1985).
-
(1985)
Evolution
, vol.39
, pp. 783-791
-
-
Felsenstein, J.1
-
19
-
-
0036336886
-
A transcriptional profile of multicellular development in Dictyostelium discoideum
-
Van Driessche, N. et al. A transcriptional profile of multicellular development in Dictyostelium discoideum. Development 129, 1543-1552 (2002).
-
(2002)
Development
, vol.129
, pp. 1543-1552
-
-
Van Driessche, N.1
-
20
-
-
0031930885
-
A cAMP-phosphodiesterase controls PKA-dependent differentiation
-
Shaulsky, G., Fuller, D. & Loomis, W.F. A cAMP-phosphodiesterase controls PKA-dependent differentiation. Development 125, 691-699 (1998).
-
(1998)
Development
, vol.125
, pp. 691-699
-
-
Shaulsky, G.1
Fuller, D.2
Loomis, W.F.3
-
21
-
-
0026485791
-
DdPK3, which plays essential roles during Dictyostelium development, encodes the catalytic subunit of cAMP-dependent protein kinase
-
Mann, S.K.O., Yonemoto, W.M., Taylor, S.S. & Firtel, R.A. DdPK3, which plays essential roles during Dictyostelium development, encodes the catalytic subunit of cAMP-dependent protein kinase. Proc. Natl. Acad. Sci. USA 89, 10701-10705 (1992).
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 10701-10705
-
-
Mann, S.K.O.1
Yonemoto, W.M.2
Taylor, S.S.3
Firtel, R.A.4
-
22
-
-
0026590704
-
Mutation of protein kinase A causes heterochronic development of Dictyostelium
-
Simon, M.N., Pelegrini, O., Veron, M. & Kay, R.R. Mutation of protein kinase A causes heterochronic development of Dictyostelium. Nature 356, 171-172 (1992).
-
(1992)
Nature
, vol.356
, pp. 171-172
-
-
Simon, M.N.1
Pelegrini, O.2
Veron, M.3
Kay, R.R.4
-
23
-
-
0026504354
-
Structurally distinct and stage-specific adenylyl cyclase genes play different roles in Dictyostelium development
-
Pitt, G.S. et al. Structurally distinct and stage-specific adenylyl cyclase genes play different roles in Dictyostelium development. Cell 69, 305-315 (1992).
-
(1992)
Cell
, vol.69
, pp. 305-315
-
-
Pitt, G.S.1
-
24
-
-
0030873976
-
Dictyostelium development in the absence of cAMP
-
Wang, B. & Kuspa, A. Dictyostelium development in the absence of cAMP, Science 277, 251-254 (1997).
-
(1997)
Science
, vol.277
, pp. 251-254
-
-
Wang, B.1
Kuspa, A.2
-
25
-
-
1642336155
-
Functional genomic hypothesis generation and experimentation by a robot scientist
-
King, R.D. et al. Functional genomic hypothesis generation and experimentation by a robot scientist. Nature 427, 247-252 (2004).
-
(2004)
Nature
, vol.427
, pp. 247-252
-
-
King, R.D.1
-
26
-
-
0142119568
-
The PUF family of RNA-binding proteins: Does evolutionarily conserved structure equal conserved function?
-
Spassov, D.S. & Jurecic, R. The PUF family of RNA-binding proteins: does evolutionarily conserved structure equal conserved function? IUBMB Life 55, 359-366 (2003).
-
(2003)
IUBMB Life
, vol.55
, pp. 359-366
-
-
Spassov, D.S.1
Jurecic, R.2
-
27
-
-
0025748167
-
RNA regulatory elements mediate control of Drosophila body pattern by the posterior morphogen nanos
-
Wharton, R.P. & Struhl, G. RNA regulatory elements mediate control of Drosophila body pattern by the posterior morphogen nanos. Cell 67, 955-967 (1991).
-
(1991)
Cell
, vol.67
, pp. 955-967
-
-
Wharton, R.P.1
Struhl, G.2
-
28
-
-
0028987223
-
Binding of pumilio to maternal hunchback mRNA is required for posterior patterning in Drosophila embryos
-
Murata, Y. & Wharton, R.P. Binding of pumilio to maternal hunchback mRNA is required for posterior patterning in Drosophila embryos. Cell 80, 747-756 (1995).
-
(1995)
Cell
, vol.80
, pp. 747-756
-
-
Murata, Y.1
Wharton, R.P.2
-
29
-
-
0032059805
-
The Pumilio RNA-binding domain is also a translational regulator
-
Wharton, R.P., Sonoda, J., Lee, T., Patterson, M. & Murata, Y. The Pumilio RNA-binding domain is also a translational regulator. Mol. Cell 1, 863-872 (1998).
-
(1998)
Mol. Cell
, vol.1
, pp. 863-872
-
-
Wharton, R.P.1
Sonoda, J.2
Lee, T.3
Patterson, M.4
Murata, Y.5
-
30
-
-
0033569404
-
Recruitment of Nanos to hunchback mRNA by Pumilio
-
Sonoda, J. & Wharton, R.P. Recruitment of Nanos to hunchback mRNA by Pumilio. Genes Dev. 13, 2704-2712 (1999).
-
(1999)
Genes Dev.
, vol.13
, pp. 2704-2712
-
-
Sonoda, J.1
Wharton, R.P.2
-
31
-
-
0033224242
-
Maternal Pumilio acts together with Nanos in germline development in Drosophila embryos
-
Asaoka-Taguchi, M., Yamada, M., Nakamura, A., Hanyu, K, & Kobayashi, S. Maternal Pumilio acts together with Nanos in germline development in Drosophila embryos. Nat. Cell Biol. 1, 431-437 (1999).
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 431-437
-
-
Asaoka-Taguchi, M.1
Yamada, M.2
Nakamura, A.3
Hanyu, K.4
Kobayashi, S.5
-
32
-
-
19344365947
-
Extensive association of functionally and cytotopically related mRNAs with Puf family RNA-binding proteins in yeast
-
Gerber, A.P., Herschlag, D. & Brown, P.O. Extensive association of functionally and cytotopically related mRNAs with Puf family RNA-binding proteins in yeast. PLoS Biol. 2, E79 (2004).
-
(2004)
PLoS Biol.
, vol.2
-
-
Gerber, A.P.1
Herschlag, D.2
Brown, P.O.3
-
33
-
-
0020648529
-
A new class of rapid developing mutants in Dictyostelium discoideum: Implications for cyclic AMP metabolism and cell differentiation
-
Abe, K. & Yanagisawa, K. A new class of rapid developing mutants in Dictyostelium discoideum: Implications for cyclic AMP metabolism and cell differentiation. Dev. Biol. 95, 200-210 (1983).
-
(1983)
Dev. Biol.
, vol.95
, pp. 200-210
-
-
Abe, K.1
Yanagisawa, K.2
-
34
-
-
84888018625
-
GenePath: A computer program for genetic pathway discovery from mutant data
-
Demsar, J. et al. GenePath: a computer program for genetic pathway discovery from mutant data. Medinfo 10, 956-959 (2001).
-
(2001)
Medinfo
, vol.10
, pp. 956-959
-
-
Demsar, J.1
-
35
-
-
0001019046
-
YakA, a protein kinase required for the transition from growth to development in Dictyostelium
-
Souza, G.M., Lu, S. & Kuspa, A. YakA,a protein kinase required for the transition from growth to development in Dictyostelium. Development 125, 2291-2302 (1998).
-
(1998)
Development
, vol.125
, pp. 2291-2302
-
-
Souza, G.M.1
Lu, S.2
Kuspa, A.3
-
36
-
-
0028979225
-
A protein kinase from Dictyostelium discoideum with an unusual acidic repeat domain
-
Wetterauer, B.W. et al. A protein kinase from Dictyostelium discoideum with an unusual acidic repeat domain. Biochim. Biophys. Acta 1265, 97-101 (1995).
-
(1995)
Biochim. Biophys. Acta
, vol.1265
, pp. 97-101
-
-
Wetterauer, B.W.1
-
37
-
-
0030448648
-
Developmental signal transduction pathways uncovered by genetic suppressors
-
Shaulsky, G., Escalante, R. & Loomis, W.F. Developmental signal transduction pathways uncovered by genetic suppressors. Proc. Natl. Acad. Sci. USA 93, 15260-15265 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 15260-15265
-
-
Shaulsky, G.1
Escalante, R.2
Loomis, W.F.3
-
38
-
-
0036464017
-
CulB, a putative ubiquitin ligase subunit, regulates prestalk cell differentiation and morphogenesis in Dictyostelium spp
-
Wang, B. & Kuspa, A. CulB, a putative ubiquitin ligase subunit, regulates prestalk cell differentiation and morphogenesis in Dictyostelium spp. Euk. Cell 1, 126-136 (2002).
-
(2002)
Euk. Cell
, vol.1
, pp. 126-136
-
-
Wang, B.1
Kuspa, A.2
-
39
-
-
0023073916
-
Cultivation and synchronous morphogenesis of Dictyostelium under controlled experimental conditions
-
(ed. Spudich, J.A.) (Academic, Orlando, Florida)
-
Sussman, M. Cultivation and synchronous morphogenesis of Dictyostelium under controlled experimental conditions, in Methods in Cell Biology (ed. Spudich, J.A.) 9-29 (Academic, Orlando, Florida, 1987).
-
(1987)
Methods in Cell Biology
, pp. 9-29
-
-
Sussman, M.1
-
40
-
-
0027483890
-
Cell type regulation in response to expression of ricin-A in Dictyostelium
-
Shaulsky, G. & Loomis, W.F. Cell type regulation in response to expression of ricin-A in Dictyostelium. Dev. Biol. 160, 85-98 (1993).
-
(1993)
Dev. Biol.
, vol.160
, pp. 85-98
-
-
Shaulsky, G.1
Loomis, W.F.2
-
41
-
-
0038642514
-
A novel developmental mechanism in Dictyostelium revealed in a screen for communication mutants
-
Kibler, K. et al. A novel developmental mechanism in Dictyostelium revealed in a screen for communication mutants. Dev. Biol. 259, 193-208 (2003).
-
(2003)
Dev. Biol.
, vol.259
, pp. 193-208
-
-
Kibler, K.1
-
42
-
-
0344925819
-
A cell-adhesion pathway regulates intercellular communication during Dictyostelium development
-
Kibler, K., Svetz, J., Nguyen, T.L., Shaw, C. & Shaulsky, G. A cell-adhesion pathway regulates intercellular communication during Dictyostelium development. Dev. Biol. 264, 506-521 (2003).
-
(2003)
Dev. Biol.
, vol.264
, pp. 506-521
-
-
Kibler, K.1
Svetz, J.2
Nguyen, T.L.3
Shaw, C.4
Shaulsky, G.5
-
43
-
-
2342593128
-
An orderly retreat: Dedifferentiation is a regulated process
-
Katoh, M. et al. An orderly retreat: dedifferentiation is a regulated process. Proc. Natl. Acad. Sci. USA 101, 7005-7010 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 7005-7010
-
-
Katoh, M.1
-
44
-
-
28744458859
-
Bioconductor: Open software development for computational biology and bioinformatics
-
Gentleman, R.C. et al. Bioconductor: open software development for computational biology and bioinformatics. Genome Biol. 5, R80 (2004).
-
(2004)
Genome Biol.
, vol.5
-
-
Gentleman, R.C.1
-
45
-
-
0032525229
-
An intersection of the cAMP/PKA and two-component signal transduction systems in Dictyostelium
-
Thomason, P.A. et al. An intersection of the cAMP/PKA and two-component signal transduction systems in Dictyostelium. EMBO J. 17, 2838-2845 (1998).
-
(1998)
EMBO J.
, vol.17
, pp. 2838-2845
-
-
Thomason, P.A.1
-
46
-
-
0022666313
-
Detection and developmental regulation of the mRNA for the regulatory subunit of the cAMP-dependent protein kinase of Dictyostelium discoideum by cell-free translation
-
de Gunzburg, J., Franke, J., Kessin, R.H. & Veron, M. Detection and developmental regulation of the mRNA for the regulatory subunit of the cAMP-dependent protein kinase of Dictyostelium discoideum by cell-free translation. EMBO J. 5, 363-367 (1986).
-
(1986)
EMBO J.
, vol.5
, pp. 363-367
-
-
De Gunzburg, J.1
Franke, J.2
Kessin, R.H.3
Veron, M.4
-
47
-
-
0026640855
-
Overexpression of DdPK 2 protein kinase causes rapid development and affects the intracellular cAMP pathway of Dictyostelium discoideum
-
Anjard, C., Pinaud, S., Kay, R.R. & Reymond, C.D. Overexpression of DdPK2 protein kinase causes rapid development and affects the intracellular cAMP pathway of Dictyostelium discoideum. Development 115, 785-790 (1992).
-
(1992)
Development
, vol.115
, pp. 785-790
-
-
Anjard, C.1
Pinaud, S.2
Kay, R.R.3
Reymond, C.D.4
|