Simultaneous selection of the wild-type genotypes of the G894T and 4B/ 4A polymorphisms of NOS3 associate with high-altitude adaptation

Annals of Human Genetics

Volumn 69, Issue 3, 2005, Pages 260-267

  Ahsan, A ^a,c   Norboo, T ^b,d   Baig, M A ^c   Pasha, M A Qadar ^a  

^a CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

^b SNM Hospital   (India)

^c HAMDARD UNIVERSITY   (India)

^d Ladakh Heart Foundation   (India)

Author keywords

Genotype combination; High altitude adaptation; Natural selection; NO levels; NOS3 polymorphisms; Wild type alleles

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE;

ADULT; ALLELE; ALTITUDE ACCLIMATIZATION; AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; DEMOGRAPHY; EQUILIBRIUM CONSTANT; EVOLUTIONARY ADAPTATION; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENETIC SCREENING; GENOTYPE; GENOTYPE PHENOTYPE CORRELATION; HOMOZYGOTE; HUMAN; INDIAN; MALE; NATURAL SELECTION; PRIORITY JOURNAL; QUESTIONNAIRE; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; WILD TYPE;

EID: 18144415472     PISSN: 00034800     EISSN: None     Source Type: Journal    
DOI: 10.1046/J.1469-1809.2005.00158.x     Document Type: Article

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