Gonadotropin-releasing hormone (GnRH) analogues and the ovary: Do GnRH antagonists destroy primordial follicles?

Fertility and Sterility

Volumn 83, Issue 5, 2005, Pages 1339-1342

  Gupta, Rupesh K ^a   Flaws, Jodi A ^a,b  

^a UNIVERSITY OF MARYLAND   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CETRORELIX; CYCLOPHOSPHAMIDE; GONADORELIN AGONIST; GONADORELIN ANTAGONIST; GONADORELIN DERIVATIVE; GONADOTROPIN; ITURELIX; LEUPRORELIN;

APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CELL DEATH; CHEMOTHERAPY; DISEASE EXACERBATION; DRUG DOSE REGIMEN; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG RESPONSE; DRUG USE; ESTRUS CYCLE; GENITAL SYSTEM; GONADOTROPIN RELEASE; HORMONE SYNTHESIS; HUMAN; HYPOGONADOTROPIC HYPOGONADISM; HYPOTHESIS; NONHUMAN; OVARY; OVARY DISEASE; OVARY FOLLICLE; OVULATION; PRIORITY JOURNAL; PROSTATE CANCER; RECEPTOR DOWN REGULATION; REPRODUCTION; SPECIES COMPARISON;

EID: 18144398972     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2005.01.089     Document Type: Article

References (22)

1. N. Pitteloud, F.J. Hayes, A. Dwyer, P.A. Boepple, H. Lee, W.F. Crowley Jr Predictors of outcome of long-term GnRH therapy in men with idiopathic hypogonadotropic hypogonadism J Clin Endocrinol Metab 87 2002 4128 4136
2. F. Antoniazzi, G. Zamboni Central precocious puberty: current treatment options Paediatr Drugs 6 2004 211 231
3. E.G. Hughes, D.M. Fedorkow, S. Daya, M.A. Sagle, P. Van de Koppel, J.A. Collins The routine use of gonadotropin-releasing hormone agonists prior to in vitro fertilization and gamete intrafallopian transfer: a meta-analysis of randomized controlled trials Fertil Steril 58 1992 888 896
4. S. Kraus, G. Levy, T. Hanoch, Z. Naor, R. Seger Gonadotropin-releasing hormone induces apoptosis of prostate cancer cells: role of c-Jun NH2-terminal kinase, protein kinase B, and extracellular signal-regulated kinase pathways Cancer Res 64 2004 5736 5744
5. J.F. Robertson, R.W. Blamey The use of gonadotrophin-releasing hormone (GnRH) agonists in early and advanced breast cancer in pre- and perimenopausal women Eur J Cancer 39 2003 861 869
6. R.M. Janssens, L. Brus, D.J. Cahill, J.A. Huirne, J. Schoemaker, C.B. Lambalk Direct ovarian effects and safety aspects of GnRH agonists and antagonists Hum Reprod Update 6 2000 505 518
7. L.L. Hall, J.M. Malone, K.A. Ginsburg Flare-up of endometriosis induced by gonadotropin-releasing hormone agonist leading to bowel obstruction Fertil Steril 64 1995 1204 1206
8. L.P. Cheung, P.M. Lam, I.H. Lok, T.T. Chiu, S.Y. Yeung, C.C. Tjer GnRH antagonist versus long GnRH agonist protocol in poor responders undergoing IVF: a randomized controlled trial Hum Reprod 20 2005 616 621
9. J. Itskovitz-Eldor, S. Kol, B. Mannaerts Use of a single bolus of GnRH agonist triptorelin to trigger ovulation after GnRH antagonist ganirelix treatment in women undergoing ovarian stimulation for assisted reproduction, with special reference to the prevention of ovarian hyperstimulation syndrome: preliminary report: short communication Hum Reprod 15 2000 1965 1968
10. K. Diedrich, C. Diedrich, E. Santos, C. Zoll, S. al-Hasani, T. Reissmann Suppression of the endogenous luteinizing hormone surge by the gonadotrophin-releasing hormone antagonist Cetrorelix during ovarian stimulation Hum Reprod 9 1994 788 791
11. K. Ataya, L.V. Rao, E. Lawrence, R. Kimmel Luteinizing hormone-releasing hormone agonist inhibits cyclophosphamide-induced ovarian follicular depletion in rhesus monkeys Biol Reprod 52 1995 365 372
12. Z. Blumenfeld, I. Avivi, S. Linn, R. Epelbaum, M. Ben-Shahar, N. Haim Prevention of irreversible chemotherapy-induced ovarian damage in young women with lymphoma by a gonadotrophin-releasing hormone agonist in parallel to chemotherapy Hum Reprod 11 1996 1620 1626
13. Danforth DR, Arbogasta LK, Friedman CI. Acute depletion of murine primordial follicle reserve by gonadotropin-releasing hormone antagonists. Fertil Steril 2005;83:1333-8.
14. T. Yano, N. Yano, H. Matsumi, Y. Morita, O. Tsutsumi, A.V. Schally Effect of luteinizing hormone-releasing hormone analogs on the rat ovarian follicle development Horm Res 48 Suppl 3 1997 35 41
15. F. Parborell, G. Irusta, A. Vitale, O. Gonzalez, A. Pecci, M. Tesone Gonadotropin-releasing hormone antagonist antide inhibits apoptosis of preovulatory follicle cells in rat ovary Biol Reprod 72 2005 659 666
16. Z. Naor, M. Zilberstein, H. Zakut, H.R. Lindner, N. Dekel Dissociation between the direct stimulatory and inhibitory effects of a gonadotropin- releasing hormone analog on ovarian functions Mol Cell Endocrinol 31 1983 261 270
17. S.K. Kang, K.C. Choi, H.S. Yang, P.C. Leung Potential role of gonadotrophin-releasing hormone (GnRH)-I and GnRH-II in the ovary and ovarian cancer Endocr Relat Cancer 10 2003 169 177
18. A.N. Hirshfield Development of follicles in the mammalian ovary Int Rev Cytol 124 1991 43 101
19. J.A. Flaws, R. Abbud, R.J. Mann, J.H. Nilson, A.N. Hirshfield Chronically elevated luteinizing hormone depletes primordial follicles in the mouse ovary Biol Reprod 57 1997 1233 1237
20. D. Meirow, G. Assad, J. Dor, J. Rabinovici The GnRH antagonist cetrorelix reduces cyclophosphamide-induced ovarian follicular destruction in mice Hum Reprod 19 2004 1294 1299
21. G.S. Harrison, M.E. Wierman, T.M. Nett, L.M. Glode Gonadotropin-releasing hormone and its receptor in normal and malignant cells Endocr Relat Cancer 11 2004 725 748
22. A.C. Bauer-Dantoin, J.L. Jameson Gonadotropin-releasing hormone receptor messenger ribonucleic acid expression in the ovary during the rat estrous cycle Endocrinology 136 1995 4432 4438