Regulation of glutamate carboxypeptidase II hydrolysis of N-acetylaspartylglutamate (NAAG) in crayfish nervous tissue is mediated by glial glutamate and acetylcholine receptors

Journal of Neurochemistry

Volumn 93, Issue 3, 2005, Pages 605-610

  Urazaev, Albert K ^a   Grossfeld, Robert M ^b   Lieberman, Edward M ^c  

^a PURDUE UNIVERSITY   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c EAST CAROLINA UNIVERSITY   (United States)

Author keywords

2 (phosphonomethyl) pentanedioic acid; Glutamate carboxypeptidase II; Group II metabotrophic glutamate receptor; N acetylaspartylglutamate; Nicotinic acetylcholine receptor; NMDA receptor

Indexed keywords

2 (PHOSPHONOMETHYL) PENTANEDIOIC ACID; CHOLINERGIC RECEPTOR; GLUTAMATE CARBOXYPEPTIDASE II; GLUTAMATE CARBOXYPEPTIDASE II INHIBITOR; GLUTAMATE RECEPTOR; GLUTARIC ACID; METABOTROPIC RECEPTOR 2; N ACETYLASPARTYLGLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CRAYFISH; ELECTROSTIMULATION; ENZYME REGULATION; GLIA CELL; HYDROLYSIS; NERVE CONDUCTION; NERVOUS TISSUE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ANIMALS; ASTACOIDEA; DIPEPTIDES; EXCITATORY AMINO ACID ANTAGONISTS; GLUTAMATE CARBOXYPEPTIDASE II; HYDROLYSIS; NEUROGLIA; NEURONS; RECEPTORS, CHOLINERGIC; RECEPTORS, METABOTROPIC GLUTAMATE;

ASTACOIDEA;

EID: 18144396898     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2005.03041.x     Document Type: Article

References (25)

1. 3H]glutamate suggests a mechanism of inactivation of an excitatory neuropeptide. J. Neurochem. 47, 1013-1019.
2. Buttram J. G. Jr, Engler J. A., Urazaev A. Kh, Grossfeld R. M. and Lieberman E. M. (2002) Uptake and metabolism of glutamine at non-synaptic regions of crayfish central nerve fibers: implications for axon-glia signaling. Comp. Biochem. Physiol. 133B, 209-220.
3. Cassidy M. and Neale J. H. (1993) N-acetylaspartylglutamate catabolism is achieved by an enzyme on the cell surface of neurons and glia. Neuropeptides 24, 271-278.
4. Coyle J. T. (1997) The nagging question of the function of N-acetylaspartylglutamate. Neurobiol. Dis. 4, 231-238.
5. Flores C. and Coyle J. T. (2003) Regulation of glutamate carboxypeptidase II function in corticolimbic regions of rat brain by phencyclidine, haloperidol and clozapine. Neuropsychopharmacology 28, 1227-1234.
6. Fuhrman S., Palkovitz M., Cassidy M. and Neale J. H. (1994) The regional distribution of N-acetylaspartylglutamate (NAAG) and peptidase activity against NAAG in the rat nervous system. J. Neurochem. 62, 775-781.
7. Gafurov B., Urazaev A. K., Grossfeld R. M. and Lieberman E. M. (2001) N-acetylaspartylglutamate (NAAG) is the probable mediator of axon-to-glia signaling in the crayfish medial giant nerve fiber. Neuroscience 106, 227-235.
8. Ghadge G. D., Slusher B. S., Bodner A. et al. (2003) Glutamate carboxypeptidase II inhibition protects motor neurons from death in familial amyotrophic lateral sclerosis models. Proc. Natl Acad. Sci. USA 300, 9554-9559.
9. A α6 subunit in cerebellar granule cells. J. Neurochem. 69, 2326-2335.
10. + homeostasis. II. The effect of axonal stimulation, cholinergic agents and transport inhibition on the resistance in series with the axon membrane. Neuroscience 53, 961-969.
11. Jackson P. F. and Slusher B. S. (2001) Design of NAALADase inhibitors: a novel neuroprotective strategy. Curr. Med. Chem. 8, 949-957.
12. Jatzke C., Wollenburg C. and Parsons C. G. (2004) The influence of N-acetyl-aspartyl-glutamate (NAAG) concentrations on the potency of N-acylated alpha-linked 1-amino dipeptidase (NAALADase) inhibitors. Trans. Soc. Neurosci. 34, 627.3.
13. Kane L. S., Butram J. G. Jr, Urazaev A. K., Lieberman E. M. and Grossfeld R. M. (2000) Uptake and metabolism of glutamate at non-synaptic regions of crayfish central nerve fibers: implications for axon-glia signaling. Neuroscience 97, 601-609.
14. + homeostasis. III. The effect of anisosmotic media and potassium on the relationship between the resistance in series with the axon membrane and glial cell volume. Neuroscience 53, 971-981.
15. Lieberman E. M. and Sanzenbacher E. (1992) Mechanisms of glutamate activation of axon-to-Schwann cell signaling in the squid. Neuroscience 47, 931-939.
16. Lieberman E. M., Hargittai P. T. and Grossfeld R. M. (1994) Electrophysiological and metabolic interactions between axons and glia in crayfish and squid. Prog. Neurobiol. 44, 333-376.
17. Neale J. T., Bzedga T. and Wroblewska B. (2000) N- acetylaspartylglutamate: the most abundant peptide neurotransmitter in the mammalian central nervous system. J. Neurochem. 75, 443-452.
18. Slusher B. S., Robinson M. B., Tsai G., Simmons M. L., Richards S. S. and Coyle J. T. (1990) Rat brain N-acetylated alpha-linked acidic dipeptidase activity. Purification and immunologic characterization. J. Biol. Chem. 265, 21 297-21 301.
19. Slusher B. S., Vornov J. J., Thomas A. G. et al. (1999) Selective inhibition of NAALADase, which converts NAAG to glutamate, reduces ischemic brain injury. Nat. Med. 5, 1396-1402.
20. Tiffany C. W., Cai N. S., Rojas C. and Slusher B. S. (2001) Binding of the glutamate carboxypeptidase II (NAALADase) inhibitor 2-PMPA to rat brain membranes. Eur. J. Pharmacol. 427, 91-96.
21. Urazaev A. Kh, Buttram J. G. Jr, Deen J. P., Gafurov B., Slusher B. S., Grossfeld R. M. and Lieberman E. M. (2001a) Mechanisms for clearance of released N-acetylaspartylglutamate in crayfish nerve fibers: implications for axon-glia signaling. Neuroscience 107, 697-703.
22. Urazaev A. Kh, Grossfeld R. M., Fletcher P. L. Jr, Speno H., Gafurov B. Sh, Buttram J. G. Jr and Lieberman E. M. (2001b) Synthesis and release of N-acetylaspartylglutamate (NAAG) by crayfish nerve fibers: implications for axon-glia signaling. Neitroscience 106, 237-247.
23. Werman R. (1966) Criteria for identification of a central nervous system transmitter. Comp. Biochem. Physiol. 18, 745-766.
24. Williamson L. C., Eagles D. A., Brady M. J., Moffett J. R., Namboodiri M. A. A. and Neale J. H. (1991) Localization and synaptic release of W-acetylaspartylglutamate in the chick retina and optic tectum. Eur. J. Neurosci. 3, 441-451.
25. Wroblewska B., Wroblewska J. T., Pshenchkin S., Surin A., Sullivan S. E. and Neale J. T. (1998) N-acetylaspartylglutamate selectively activates mGLUR3 receptors in transfected cells. J. Neurochem. 69, 174-181.