Atypical angiomyolipoma of kidney in a patient with tuberous sclerosis: A case report with p53 gene mutation analysis

Archives of Pathology and Laboratory Medicine

Volumn 129, Issue 5, 2005, Pages 676-679

  Ma, Linglei ^a   Kowalski, Diane ^a   Javed, Khurram ^a   Hui, Pei ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOSE TISSUE; ADULT; ANGIOMYOLIPOMA; ARTICLE; BLOOD VESSEL; CANCER GROWTH; CASE REPORT; EXON; FEMALE; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOREACTIVITY; KIDNEY TUMOR; MITOSIS; SINGLE NUCLEOTIDE POLYMORPHISM; SMOOTH MUSCLE FIBER; TUBEROUS SCLEROSIS;

ADULT; ANGIOMYOLIPOMA; CYTOPLASM; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; FEMALE; GENES, P53; HUMANS; IMMUNOHISTOCHEMISTRY; INTERCELLULAR JUNCTIONS; KIDNEY NEOPLASMS; MUTATION; NEPHRECTOMY; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; TREATMENT OUTCOME; TUBEROUS SCLEROSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 18144387593     PISSN: 00039985     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Al-Saleem T, Wessner LL, Scheithauer BW, et al. Malignant tumors of the kidney, brain, and soft tissues in children and young adults with the tuberous sclerosis complex. Cancer. 1998;83:2208-2216.
2. Carbonara C, Longa L, Grosso E, et al. Apparent preferential loss of heterozygosity at TSC2 over TSC1 chromosomal region in tuberous sclerosis hamartomas. Genes Chromosomes Cancer. 1996;15:18-25.
3. Pea M, Bonetti F, Zamboni G, et al. Melanocyte-marker-HMB-45 is regularly expressed in angiomyolipoma of the kidney. Pathology. 1991;23:185-188.
4. Delgado R, de Leon Bojorge B, Albores-Saavedra J. Atypical angiomyolipoma of the kidney: a distinct morphologic variant that is easily confused with a variety of malignant neoplasms. Cancer. 1998;83:1581-1592.
5. Martignoni G, Bonetti F, Pea M, Tardanico R, Brunelli M, Eble JN. Renal angiomyolipoma with epithelioid sarcomatous transformation and metastases. Am J Surg Pathol. 2000;24:889-894.
6. Kawaguchi K, Oda Y, Nakanishi K, et al. Malignant transformation of renal angiomyolipoma: a case report. Am J Surg Pathol. 2002;26:523-529.
7. Dillon D, Zhang K, Costa J. Rapid, efficient genotyping of clinical tumor samples by laser-capture microdissection/PCR/SSCP. Exp Mol Pathol. 2001;70:195-200.
8. Vang R, Kempson RL. Perivascular epithelioid cell tumor (PEComa) of the uterus. Am J Surg Pathol. 2002;26:1-13.
9. Bonetti F, Pea M, Martignoni G, et al. Clear cell ("sugar") tumor of the lung is a lesion strictly related to angiomyolipoma: the concept of a family of lesions characterized by the presence of the perivascular epithelioid cells (PEC). Pathology. 1994;26:230-236.
10. L'Hostis H, Deminiere C, Ferriere JM, Coindre JM. Renal angiomyolipoma: a clinicopathologic, immunohistochemical, and follow-up study of 46 cases. Am J Surg Pathol. 1999;23:1011-1020.
11. Cibas ES, Goss GA, Kulke MH, Demetri GD, Fletcher CD. Malignant epithelioid angiomyolipoma ('sarcoma ex angiomyolipoma') of the kidney: a case report and review of the literature. Am J Surg Pathol. 2001;25:121-126.
12. Nigro JM, Baker SJ, Preisinger AC, et al. Mutations in the p53 gene occur in diverse human tumour types. Nature. 1989;342:705-708.
13. Rocken C, Schneider-Stock R, Buhtz P, Manger T, Roessner A. Hepatic angiomyolipoma in a 26-year-old Caucasian woman with a history of tibial osteosarcoma. Pathol Res Pract. 1999;195:765-772.
14. Saito M, Tsukamoto T, Takahashi T, Sai K, Fujii H, Nagashima K. Multifocal angiomyolipoma affecting the liver and lung without tuberous sclerosis. J Clin Pathol. 2004;57:221-224.
15. Park SH, Ro JY, Kim HS, Lee ES. Perivascular epithelioid cell tumor of the uterus: immunohistochemical, ultrastructural and molecular study. Pathol Int. 2003;53:800-805.