Cytokine amplification by respiratory syncytial virus infection in human nasal epithelial cells

Laryngoscope

Volumn 115, Issue 5, 2005, Pages 764-768

  Das, Subinoy ^a   Palmer, Owen P ^a   Leight, W Derek ^a   Surowitz, Joshua B ^a   Pickles, Raymond J ^b   Randell, Scott H ^b   Buchman, Craig A ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

IL 6; IL 8; Nasal epithelium; RANTES; Respiratory syncytial virus; RSV; TNF

Indexed keywords

CYTOKINE; INTERLEUKIN 6; INTERLEUKIN 8; RANTES; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMAN; HUMAN CELL; MUCUS SECRETION; NOSE MUCOSA; OTITIS MEDIA; PATHOGENESIS; PNEUMONIA; PRIORITY JOURNAL; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHINITIS; SINUSITIS; UPPER RESPIRATORY TRACT INFECTION; VIRUS INFECTION;

ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; NASAL MUCOSA; OTITIS MEDIA; PNEUMONIA; RANTES; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 18044388358     PISSN: 0023852X     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.MLG.0000159527.76949.93     Document Type: Article

References (15)

1. Garofalo RP, Haeberle H. Epithelial regulation of innate immunity to respiratory syncytial virus. Am J Respir Cell Mol Biol 2000;23:581-585.
2. Noah TL, Ivins SS, Murphy P, et al. Chemokines and inflammation in the nasal passages of infants with respiratory syncytial virus bronchiolitis. Clin Immunol 2002;104:86-95.
3. Bakaletz LO. Viral potentiation of bacterial superinfection of the respiratory tract [review]. Trends Microbiol 1995;3:110-114.
4. Zhang L, Peeples ME, Boucher RC, et al. Respiratory syncytial virus infection of human airway epithelial cells is polarized, specific to ciliated cells, and without obvious cytopathology. J Virol 2002;76:5654-5666.
5. Wu R, Yankaskas J, Cheng E, et al. Growth and differentiation of human nasal epithelial cells in culture: serum-free, hormone-supplemented medium and proteoglycan synthesis. Am Rev Respir Dis 1985;132:311-320.
6. Pickles RJ, McCarty D, Matsui H, et al. Limited entry of adenovirus vectors into well-differentiated airway epithelium is responsible for inefficient gene transfer. J Virol 1998;72:6014-6023.
7. Haeberle HA, Takizawa R, Casola A, et al. Respiratory syncytial virus-induced activation of nuclear factor-kappaB in the lung involves alveolar macrophages and toll-like receptor 4-dependent pathways. J Infect Dis 2002;186:1199-1206.
8. Kim HS, Lee G, John SW, et al. Molecular phenotyping for analyzing subtle genetic effects in mice: application to an angiotensinogen gene titration. Proc Nat Acad Sci USA 2002;99:4602-4607.
9. Patel JA, Jiang Z, Nakajima N, Kunimoto M. Autocrine regulation of interleukin-8 by interleukin-lalpha in respiratory syncytial virus-infected pulmonary epithelial cells in vitro. Immunology 1998;95:501-506.
10. Buchman CA, Doyle WJ, Pilcher O, et al. Nasal and otologic effects of experimental respiratory syncytial virus infection in adults. Am J Otolaryngol 2002;23:70-75.
11. Varga SM, Braciale TJ. RSV-induced immunopathology: dynamic interplay between the virus and host immune response. Virology 2002;295:203-207.
12. Zhang Y, Luxon BA, Casola A, et al. Expression of respiratory syncytial virus-induced chemokine gene networks in lower airway epithelial cells revealed by cDNA microarrays. J Virol 2001;75:9044-9058.
13. Gentile DA, Doyle WJ, Zeevi A, et al. Cytokine gene polymorphisms moderate illness severity in infants with respiratory syncytial virus infection. Hum Immunol 2003;64:338-344.
14. Thomas LH, Wickremasinghe MI, Sharland M, Friedland JS. Synergistic upregulation of interleukin-8 secretion from pulmonary epithelial cells by direct and monocyte-dependent effects of respiratory syncytial virus infection. J Virol 2000;74:8425-8433.
15. Casola A, Henderson A, Liu T, et al. Regulation of RANTES promoter activation in alveolar epithelial cells after cytokine stimulation. Am J Physiol Lung Cell Mol Physiol 2002;283:L1280-1290.