Synthesis and anti-HIV activity of 1,3,4,5-tetrahydro-2H-1,4- benzodiazepin-2-one (TBO) derivatives. Truncated 4,5,6,7-tetrahydro-5- methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-ones (TIBO) analogues

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 11, 1999, Pages 2427-2436

  Breslin, Henry J ^a   Kukla, Michael J ^a   Kromis, Teresa ^a   Cullis, Heather ^a   De Knaep, Fons ^b   Pauwels, Rudi ^c   Andries, Koen ^b   De Clercq, Erik ^d   Janssen, Marcel A C ^b   Janssen, Paul A J ^b  

^a JANSSEN RESEARCH AND DEVELOPMENT   (United States)

^b JANSSEN RESEARCH FOUNDATION   (Belgium)

^c TIBOTEC BVBA   (Belgium)

^d REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

AIDS; Antiviral; HIV

Indexed keywords

1,3,4,5 TETRAHYDRO 2H 1,4 BENZODIAZEPINE 2 ONE; ANTIVIRUS AGENT; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG PURIFICATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; STRUCTURE ANALYSIS; VIRUS REPLICATION;

ANTI-HIV AGENTS; BENZODIAZEPINONES; CELLS, CULTURED; HIV-1; HUMANS; IMIDAZOLES; STRUCTURE-ACTIVITY RELATIONSHIP;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 17944391288     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(99)00198-4     Document Type: Article

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