Changes in the number of CD80+, CD86+, and CD28+ peripheral blood lymphocytes have prognostic value in melanoma patients

Human Immunology

Volumn 64, Issue 8, 2003, Pages 796-801

  Martínez Escribano, Jorge A ^a   Hernández Caselles, Trinidad ^a   Campillo, José A ^a   Campos, Matilde ^b   Frías, José F ^a   García Alonso, Ana ^a   Alvarez López, M Rocío ^a,b  

^a UNIVERSITY OF MURCIA   (Spain)

^b HOSPITAL UNIVERSITARIO VIRGEN DE LA ARRIXACA   (Spain)

Author keywords

CD28 antigen; CD8 suppressor T cell; CD80 antigen; CD86 antigen; Melanoma

Indexed keywords

B7 2 PROTEIN; B7 ANTIGEN; B7-2 PROTEIN; CD19 ANTIGEN; CD28 ANTIGEN; CD3 ANTIGEN; CD8 ANTIGEN; CD86 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; LEUKOCYTE ANTIGEN; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY;

ADULT; ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; ARTICLE; B LYMPHOCYTE; CANCER SURVIVAL; CELL SUBPOPULATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOLOGY; LYMPHOCYTE; LYMPHOCYTE COUNT; MALE; MELANOMA; PATHOLOGY; PRIORITY JOURNAL; PROGNOSIS; SUPPRESSOR CELL; T LYMPHOCYTE SUBPOPULATION;

EID: 17944390951     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(03)00122-8     Document Type: Article

References (27)

1. Nestle FO, Burg G, Dummer R: New perspectives on immunobiology and immunotherapy of melanoma. Immunol Today 20:5, 1999.
2. + T cells. J Exp Med 188:1977, 1998.
3. Kim CW, Choi SH, Chung EJ, Lee MJ, Byun EK, Ryu M, Bang YG: Alteration of signal-transducing molecules and phenotypical characteristics in peripheral blood lymphocytes from gastric carcinoma patients. Pathobiology 67: 123, 1999.
4. Rao KL, Varalakshmi CH, Kumari AL, Khar A: Interaction between B.7 and CD28 costimulatory molecules is essential for the activation of effector function mediating spontaneous tumour regression. Scand J Immunol 49:633, 1999.
5. June CH, Bluestone JA, Nadler LM, Thompson CB: The B7 and CD28 receptor families. Immunol Today 15:321, 1994.
6. Boussiotis VA, Freeman GJ, Gribben JG, Nadler LM: The role of B7-1/B7-2: CD28/CTLA-4 pathways in the prevention of anergy, induction of productive immunity and down-regulation of the immune response. Immunol Rev 153:5, 1996.
7. Rulifson IC, Sperling AI, Fields PE, Fitch FW, Bluestone JA: CD-28 co-stimulation promotes the production of Th2 cytokines. J Immunol 158:658, 1997.
8. Liu Y: Is CTLA-4 a negative regulator for T-cell activation? Immunol Today 18:569, 1997.
9. Chambers CA: The expanding world of co-stimulation: the two-signal model revisited. Trends Immunol 22:217, 2001.
10. Jeannin P, Delneste Y, Lecoanet-Henchoz S, Gauchat JF, Ellis J, Bonnefoy JY: CD86 (B7-2) on human B cells. J Biol Chem 272:15613, 1997.
11. Natarajan K, Sahoo NC, Rao KVS: Signal thresholds and modular synergy during expression of costimulatory molecules in B lymphocytes. J Immunol 167:114, 2001.
12. Croft M, Joseph SB, Miner KT: Partial activation of naive CD4 T cells and tolerance induction in response to peptide presented by resting B cells. J Immunol 159:3257, 1997.
13. Balch CM, Buzaid AC, Atkins MB, Cascinelli N, Coit DG, Fleming ID, Houghton A Jr, Kirkwood JM, Mihm MF, Morton DL, Reintgen D, Ross MI, Sober A, Soong SJ, Thompson JA, Thompson JF, Gershenwald JE, McMasters KM: A new American Joint Committee on Cancer staging system for cutaneous melanoma. Cancer 88: 1484, 2000.
14. Sule-Suso J, Arienti F, Melani C, Colombo MP, Parmiani G: A B7-1-transfected human melanoma line stimulates proliferation and cytotoxicity of autologous and allogeneic lymphocytes. Eur J Immunol 25:2737, 1995.
15. Miyazono Y, Kamogawa Y, Ryo K, Furukawa T, Mitsuhashi M, Yamauchi K, Kameoka T, Hayashi N: Effect of B7.1-transfected human colon cancer cells on the induction of autologous tumor-specific cytotoxic T cells. J Gastroenterol Hepatol 14:997, 1999.
16. Mackensen A, Wittnebel S, Veelken H, Noppen C, Spagnoli GC, Lindermann A: Induction and large-scale expansion of CD8+ tumour specific cytotoxic T lymphocytes from peripheral blood lymphocytes by in vitro stimulation with CD80-transfected autologous melanoma cells. Eur Cytokine Netw 10:329, 1999.
17. Genc K, Dona DL, Reder AT: Increased CD80+ B cells in active multiple sclerosis and reversal by interferon β-1b therapy. J Clin Invest 99:2664, 1997.
18. Bijl M, Horst G, Limburg PC, Kallenberg CG: Expression of costimulatory molecules on peripheral blood lymphocytes of patients with systemic lupus erythematosus. Ann Rheum Dis 60:523, 2001.
19. Freeman GJ, Boussiotis VA, Anumanthan A, Bernstein GM, Ke XY, Rennert PD, Gray GS, Gribben JG, Nadler LM: B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4. Immunity 2:523, 1995.
20. Kuchroo VK, Das MP, Brown JA, Ranger AM, Zamvil SS, Sobel RA, Weiner HL, Nabavi N, Glimcher LH: B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 development pathway: application to autoimmune disease therapy. Cell 80:707, 1995.
21. Suvas S, Singh V, Sahdev S, Vohra H, Agrewala JN: Distinct role of CD80 and CD86 in the regulation of the activation of B cell and B cell lymphomas. J Biol Chem 277:7766, 2002.
22. Choi SH, Chung EJ, Whang DY, Lee SS, Jang Y-S, Kim CW: Alteration of signal-transducing molecules in tumor-infiltrating lymphocytes and peripheral blood T lymphocytes from human colorectal carcinoma patients. Cancer Immunol Immunother 45:299, 1998.
23. Lombard G, Sidhu S, Batchelor R, Lechler T: Anergic T cells as suppressors cells in vitro. Nature 264:1587, 1994.
24. - T supressor cells a distinct subset in a heterogeneous population. Transplant Proc 33:104, 2001.
25. Jiang S, Tugulea S, Pennesi G, Liu Z, Mulder A, Lederman S, Harris P, Cortesini R, Suciu-Foca N: Induction of MHC-class I restricted human suppressor T cells by peptide priming in vitro. Human Immunol 59:690, 1998.
26. Ciubotariu R, Vasilescu R, Ho E, et al: Detection of T suppressor cells in patients with organ allografts. Hum Immunol 62:15, 2001.
27. Li J, Liu Z, Jiang S, Cortesini R, Lederman S, Suciu-Foca N: T suppressor lymphocytes inhibit NF-κ B-mediated transcription of CD86 gene in APC. J Immunol 163: 6386, 1999.