Identification and expression of cosmids with an allelic variant of class I alcohol dehydrogenase in transgenic mice

Chemico-Biological Interactions

Volumn 130-132, Issue , 2001, Pages 481-490

  Szalai, Gabor ^a   Ceci, Jeff ^b   Dewey, Michael ^a   Felder, Michael ^a  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Alcohol dehydrogenase; Enzyme electrophoresis; Gene expression; Transgenic mice

Indexed keywords

ALCOHOL DEHYDROGENASE; MESSENGER RNA;

ALLELE; ANIMAL EXPERIMENT; ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; COSMID; DNA FLANKING REGION; FEMALE; GENE CONSTRUCT; GENE CONTROL; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC VARIABILITY; HORMONAL REGULATION; MALE; MOUSE; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PROMOTER REGION; TRANSGENE; TRANSGENIC MOUSE;

ALCOHOL DEHYDROGENASE; ALLELES; ANIMALS; COSMIDS; GENE EXPRESSION; GENES, REGULATOR; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PHENOTYPE; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PROMOTER REGIONS (GENETICS); REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TISSUE DISTRIBUTION; TRANSFECTION; VARIATION (GENETICS);

MUS MUSCULUS;

EID: 17944384581     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(00)00293-3     Document Type: Conference Paper

References (16)

1. Ten kilobases of 5′-flanking region confers proper regulation of the mouse alcohol dehydrogenase-1 (Adh-1) gene in kidney and adrenal of transgenic mice
2. Recommended nomenclature for the vertebrate alcohol dehydrogenase gene family
3. Cloning and sequencing of cDNA encoding the complete mouse liver alcohol dehydrognase
4. Androgen induction of alcohol dehydrogenase in mouse kidney. Studies with a cDNA probe confirmed by nucleotide sequence analysis
5. Mechanism of induction of mouse kidney alcohol dehydrogenas by androgen
6. Tissue-specific genetic variation in the level of mouse alcohol dehydrogenase is controlled transcriptionally in kidney and posttranscriptionally in liver
7. Cloning of the mouse class IV alcohol dehydrogenase (retinol dehydrogenase) cDNA and tissue-specific expression patterns of the murine ADH gene family
8. Genetic and developmental regulation of mouse liver alcohol dehydrogenase
9. A novel negative element in the promoter of the mouse alcohol dehydrogenase gene Adh-1
10. A negative regulatory element upstream from the mouse Adh-1 gene can down regulate a heterologous promoter
11. Protein-DNA interactions in the 5′ region of the mouse alcohol dehydrogenase gene Adh-1
12. Differential activity of the promoter for the human alcohol dehydrogenase (retinol dehydrogenase) gene ADH3 in neural tube of transgenic mouse embryos
13. Detection of specific sequences among DNA fragments separated by gel electrophoresis
14. Apolipoprotein B gene expression in a series of human apolipoprotein B transgenic mice generated with recA-assisted restriction endonuclease cleavage-modified bacterial artificial chromosomes
15. A far-downstream hepatocyte-specific control region directs expression of the linked human apolipoprotein E and C-I genes in transgenic mice
16. An albumin enhancer located 10 kb upstream functions along with its promoter to direct efficient, liver-specific expression in transgenic mice