Is the time from HIV seroconversion a determinant of the risk of AIDS after adjustment for updated CD4 cell counts?

Journal of Acquired Immune Deficiency Syndromes

Volumn 28, Issue 2, 2001, Pages 158-165

  Babiker, A ^a,a   Darbyshire, J ^a   Pezzotti, P ^a   Porter, K ^a   Rezza, G ^a   Walker, S ^a   Beral, V ^a   Coutinho, R ^a   Del Amo, J ^a   Gill, N ^a   Lee, C ^a   Meyer, L ^a   Tyrer, F ^a   Dabis, F ^a   Thiebaut, R ^a   Lawson Ayayi, S ^a   Boufassa, F ^a   Hamouda, O ^a   Lorenzo, J I ^a   Touloumi, G ^a   Hatzakis, A ^a   Karafoulidou, A ^a   Katsarou, O ^a   Brettle, R ^a   Del Romero, J ^a   Prins, M ^a   Coutinho, R A ^a   Van Benthem, B ^a   Kirk, O ^a   Pedersen, C ^a   Hernandez Aguado I ^a   Perez Hoyos S ^a   Eskild, A ^a   Bruun, J N ^a   Sannes, M ^a   Sabin, C ^a   Johnson, A M ^a   Phillips, A N ^a   Darbyshire, J H ^a   Francioli, P ^a   Vanhems, P ^a   Egger, M ^a   Rickenbach, M ^a   Cooper, D ^a   Kaldor, J ^a   Vizzard, J ^a   Tusell, J M ^a   Ruiz, I ^a   Cayla, J A ^a   Garcia de Olalla, P ^a   Day, N E ^a   De Angelis, D ^a   more..

^a MRC CLINICAL TRIALS UNIT   (United Kingdom)

Author keywords

AIDS; CD4; Cohort; HIV; Progression; Seroconverters

Indexed keywords

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; ARTICLE; CLINICAL ARTICLE; DISEASE ASSOCIATION; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; LYMPHOCYTE COUNT; MALE; PRIORITY JOURNAL; RISK ASSESSMENT; SEROCONVERSION; STATISTICAL ANALYSIS;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ADOLESCENT; ADULT; AGE DISTRIBUTION; AUSTRALIA; CD4 LYMPHOCYTE COUNT; COHORT STUDIES; CONFIDENCE INTERVALS; EUROPE; FEMALE; HEMOPHILIA A; HETEROSEXUALITY; HIV SEROPOSITIVITY; HOMOSEXUALITY, MALE; HUMANS; MALE; MIDDLE AGED; PROPORTIONAL HAZARDS MODELS; RISK FACTORS; SEXUAL BEHAVIOR; TIME FACTORS;

EID: 17944370609     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/00126334-200110010-00008     Document Type: Article

References (25)

1. Serial CD4 lymphocyte counts and the development of AIDS
2. Acquired immunodeficiency syndrome (AIDS) risk in recent and long-standing human immunodeficiency virus type 1 (HIV-1)-infected patients with similar CD4 lymphocyte counts
3. CD4 lymphocyte count as a determinant of the time from HIV seroconversion to AIDS and death from AIDS: Evidence from the Italian Seroconversion Study
4. Replacing time since human immunodeficiency virus infection by marker values in predicting residual time to acquired immunodeficiency syndrome diagnosis. Multicenter AIDS Cohort Study
5. Dependence of the hazard of AIDS on markers
6. Progression to acquired immunodeficiency syndrome is influenced by CD4 T-lymphocyte count and time since seroconversion
7. Predictive value of CD4 lymphocyte numbers for the development of opportunistic infections and malignancies in HIV-infected persons
8. Changes in the uptake of antiretroviral therapy and survival in persons with known duration of HIV infection in Europe
9. Time from HIV-1 seroconversion to AIDS and death before the widespread use of highly active anti-retroviral therapy: A collaborative reanalysis
10. Regression models and life tables
11. Expanded European AIDS case definition
12. Clinical characteristics and prognostic value of acute retroviral syndrome among injecting drug users. Italian Seroconversion Study
13. How reliable are data on HIV seroconversion illness? Is HIV test interval an adequate substitute?
14. Flexible regression models with cubic splines
15. Time-varying explanatory variables
16. The behavior of maximum likelihood estimates under non-standard conditions
17. Regression analysis of multivariate incomplete failure time data by modeling marginal distributions
18. + cell count measurement variability on staging HIV-1 infection
19. Bias in relative odds estimation owing to imprecise measurement of correlated exposures
20. + lymphocyte count at diagnosis of acquired immunodeficiency syndrome
21. Human herpesvirus 8 seropositivity and risk of Kaposi's sarcoma and other acquired immunodeficiency syndrome-related diseases
22. Seroconversion for human herpesvirus 8 during HIV infection is highly predictive of Kaposi's sarcoma
23. Regression of AIDS-related Kaposi's sarcoma associated with clearance of human herpesvirus-8 from peripheral blood mononuclear cells following initiation of antiretroviral therapy