Pyridopyrimidine analogues as novel adenosine kinase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 16, 2001, Pages 2071-2074

  Zheng, Guo Zhu ^a   Lee, Chih Hung ^a   Pratt, John K ^a   Perner, Richard J ^a   Jiang, Mei Qun ^a   Gomtsyan, Arthur ^a   Matulenko, Mark A ^a   Mao, Yui ^a   Koenig, John R ^a   Kim, Ki H ^a   Muchmore, Steve ^a   Yu, Haixia ^a   Kohlhaas, Kathy ^a   Alexander, Karen M ^a   McGaraughty, Steve ^a   Chu, Katharine L ^a   Wismer, Carol T ^a   Mikusa, Joseph ^a   Jarvis, Michael F ^a   Marsh, Kennan ^a   Kowaluk, Elizabeth A ^a   Bhagwat, Shripad S ^a   Stewart, Andrew O ^a   more..

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYPIPERIDNYLDERIVATIVE; ACETAL; ADENOSINE KINASE; ADENOSINE KINASE INHIBITOR; CARRAGEENAN; MORPHINE; PYRIDOPYRIMIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; DOG; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG EFFECT; DRUG HALF LIFE; DRUG POTENCY; DRUG STRUCTURE; HYPERALGESIA; IN VIVO STUDY; MATHEMATICAL COMPUTING; NONHUMAN; RAT; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

ADENOSINE KINASE; ENZYME INHIBITORS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MORPHOLINES; PYRIMIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 17944366392     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00375-4     Document Type: Article

References (20)