Renoprotective effect of early inhibition of the renin-angiotensin system in renal transplant recipients

Transplantation Proceedings

Volumn 37, Issue 2, 2005, Pages 991-993

  Montanaro, D ^a   Gropuzzo, M ^a   Tulissi, P ^a   Vallone, C ^a   Boscutti, G ^a   Mioni, R ^a   Risaliti, A ^b   Baccarani, U ^b   Adani, G L ^b   Sainz, M ^b   Bresadola, F ^b   Mioni, G ^a  

^a SANTA MARIA DELLA MISERICORDIA UNIVERSITY HOSPITAL   (Italy)

^b UNIVERSITY OF UDINE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN 2 RECEPTOR ANTAGONIST; CLONIDINE; CYCLOSPORIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DOXAZOSIN; ENALAPRIL; IMMUNOSUPPRESSIVE AGENT; LOSARTAN; MYCOPHENOLIC ACID; NIFEDIPINE; RAMIPRIL; STEROID; TACROLIMUS; VALSARTAN;

ARTERIAL PRESSURE; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; CREATININE CLEARANCE; DRUG BLOOD LEVEL; ERYTHROCYTOSIS; HUMAN; HYPERTENSION; KIDNEY FUNCTION; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; LIPID BLOOD LEVEL; PRIORITY JOURNAL; PROTEINURIA; RECIPIENT; RENAL PROTECTION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

EID: 17844391566     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2005.01.043     Document Type: Conference Paper

References (15)

1. S. Hariharan, C.P. Johnson, B.A. Bresnahan Improved graft survival after renal transplantation in the United States, 1988 to 1996 N Engl J Med 342 2000 605
2. K. Womer, J. Vella, M. Sayegh Chronic allograft dysfunction: mechanisms and new approaches to therapy Semin Nephrol 20 2000 126
3. C.E. Stigant, J. Cohen, M. Vivera ACE inhibitors and angiotensin-II- antagonists in renal transplantations: An analysis of safety and efficacy Am J Kidney Dis 35 2000 58
4. J. Calvino, X. Lens, R. Romero Long-term anti-proteinuric effect of losartan in renal transplant recipients treated for hypertension Nephrol Dial Transplant 15 2000 82
5. S.C. Amuchastegui, N. Azzolini, M. Mister Chronic allograft nephropathy in the rat is improved by angiotensin II receptor blockade but not by calcium channel antagonism J Am Soc Nephrol 9 1998 1945
6. J. Lin, A.M. Valeri, G.S. Markowitz Angiotensin converting-enzyme, inhibition in chronic allograft nephropathy Transplantation 73 2002 783
7. M.W. Taal, B.M. Brenner Renoprotective benefits of RAS inhibition: from ACEI to angiotensin II antagonists Kidney Int. 57 2000 1803
8. H.S. Mackenzie, B.M. Brenner Antigen-independent determinants of late renal allograft outcome: the role of renal mass Curr Opin Nephrol Hypertens 5 1996 289
9. S. Kagami, W. Border, D.E. Miller Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor-beta expression in rat glomerular mesangial cells J Clin Invest 93 1994 2431
10. W.A. Border, N.A. Noble, M. Kettler TGF-beta: a cytokine mediator of glomerulosclerosis and a target for therapeutic intervention Kidney Int 49 1995 S59
11. H. Itoh, M. Mukoyama, R.E. Pratt Multiple autocrine growth factors modulate vascular smooth muscle growth response to angiotensin II J Clin Invest 91 1993 2268
12. B. Cuhaci, M.S. Kumar, R.D. Bloom Transforming growth factor-beta levels in human allograft chronic fibrosis correlate with rate of decline in renal function Transplantation 68 1999 785
13. A. Szabo, J. Lutz, K. Schleimer Effect of angiotensin-converting enzyme inhibition on growth factor mRNA in chronic renal allograft rejection in the rat Kidney Int 57 2000 982
14. P. Inigo, J. Campistol, S. Lario Effects of losartan and amlodipine on intrarenal hemodynamics and TGF-beta 1 plasma levels in a crossover trial in renal transplant patients J Am Soc Nephrol 12 2000 822
15. M. Noris, N. Azzolini, A. Pezzotta Combined treatment with mycophenolate mofetil and an angiotensin II receptor antagonist fully protects from chronic rejections in a rat model of renal allograft J Am Soc Nephrol 12 2001 1937